2015 (104 POSTS)

Kelsh MA, Chia VM. Historical comparator studies: Strengths, limitations, and analytical considerations in using historical pooled clinical data for evaluating efficacy and safety of new therapies. Presented at International Conference on Pharmacoepidemiology and Therapeutic Risk Management (ICPE) Boston, MA, August 25, 2015.

Hughes BJ, LeBaron MJ, Thomas J, Kan HL, Lynch AM, Borghoff SJ, Green S, Mensing T, Sarang SS, Smulders CJGM. 2015. Activation of CAR and PXR nuclear receptors in the liver of MIBK-exposed mice. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

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Kirman CR, Proctor DM, Suh M, Hays S. Reduction of hexavalent chromium by gastric fluids from fed and fasted individuals with applications to toxicokinetic modeling. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

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Suh M, Mittal L, Hirsch S, Valdes R, Bartlett C, Rohr A, Proctor D. 2015. Lung cancer risk in chromate production workers exposed to hexavalent chromium. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

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Britt J, James R. 2015. Welding and occupational exposure to manganese fumes and Parkinson’s disease: An evidence-based causation analysis. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

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Doepker C, Brorby G. The role of the toxicologist in required food safety plans: A case study of ochratoxin A (OTA) in coffee. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

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Proctor D, Suh M, Thompson C, Hixon, G. Inhalation cancer risk assessment of titanium dioxide. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

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Urban JD, Thompson CM, Plunkett LM, Perry CS, Haws LC. A state of the science copper reference dose for soil remediation. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

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Harris MA, Thompson CM, Proctor DM, Suh M, Wolf JC, Seiter JM, Chappell MA, Haws LC. Analysis of duodenal crypt health following exposure to Cr(VI) in drinking water. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

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Thompson CM, Young RR, Suh M, Dinesdurage H, Elbekai R, Harris MA, Rohr AC, Proctor DM. Hexavalent chromium does not induce mutations in the oral mucosa of transgenic Big Blue® rats following drinking water exposures at a carcinogenic dose. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

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Thompson CM, Suh M, Hixon G, Bichteler A. Comparison of smoothing spline regression and conventional modeling approaches for quantitative risk sssessments of human dioxin exposure. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

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Borghoff SJ, Wikoff D, White MC, Thompson C, Haws LC. Identification of the molecular initiating event (MIE) for TBBPA induced uterine tumors in the framework of an adverse outcome pathway (AOP). Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

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Wikoff D, White MC, Borghoff SJ, Haws LC. Evaluation of tetrabromobisphenol A (TBBPA)-induced endocrine-related target gene activity using high-throughput screening data from ToxCast. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

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Wheeler MW, Shao K, Bailer AJ. 2015. Quantile benchmark dose estimation for continuous endpoints. Environmetrics 26(5):363-72; doi: 10.1002/env.2432.

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Brorby G, Suh M, Bichteler A, Proctor D. Use of cluster analysis and homogeneity testing to characterize distributions of exposures among beryllium workers: Tools for developing occupational exposure limits from quantitative risk assessment.  Presented at International Society of Exposure Science 25th Annual Meeting, Henderson, NV, October 2015.

Thompson CM, Wolf JC, Elbekai RH, Paranjpe MG, Seiter JM, Chappell MA, Tappero RV, Suh M, Proctor DM, Bichteler A, Haws LC, Harris MA. 2015. Duodenal crypt health following exposure to Cr(VI): Micronucleus scoring, γ-H2AX immunostaining, and synchrotron x-ray fluorescence microscopy. Mut Res 789–790:61–66; doi: 10.1016/j.mrgentox.2015.05.004.

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Klaren WD, Robertson LW. PCB126-mediated disruption of hepatic metal homeostasis in mice and the role of metallothionein. Society of Toxicology 54th Annual Meeting, San Diego, CA, 2015.

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Klaren WD, Vine D, Vogt S, Robertson LW. Spatial distribution of hepatic metals following PCB126 exposure. Society of Toxicology, Central States Regional Chapter Annual Meeting, Kansas City, Ks, 2015.

Gadupudi GS, Klaren WD, Olivier AK, Klingelhutz AJ, Robertson LW. PCB126-induced disruption in gluconeogenesis and fatty acid oxidation precedes fatty liver in male rats. Society of Toxicology, Central States Regional Chapter Annual Meeting, Kansas City, KS, 2015.

Gadupudi GS, Klaren WD, Olivier AK, Klingelhutz AJ, Robertson LW. PCB126-induced disruption in gluconeogenesis and fatty acid oxidation precedes fatty liver in male rats. Superfund Annual Meeting, San Juan, Puerto Rico, 2015.