Publications
food safety (28 POSTS)
2025 (2 POSTS)
Human health risk assessment of three smoke flavoring primary products
Brorby G, Franzen A, Thompson C, Wikoff D, Doepker C. 2025. Human health risk assessment of three smoke flavoring primary products. Food Chem Toxicol 202(Aug):115490; doi: 10.1016/j.fct.2025.115490. PMID: 40320068.
View AbstractA tool to support food substance safety evaluations in the United States
Crincoli CM, van de Ligt JLG, Eapen AK. Pavel AT, Hanlon PR, Almond-Abbate K, Haugabrooks E,… Henderson RG. 2025. A tool to support food substance safety evaluations in the United States. Regul Toxicol Pharmacol 161(Sept):105838; doi: 10.1016/j.yrtph.2025.105838. PMID: 40324559.
View Abstract2023 (3 POSTS)
Reassessment of the cadmium toxicological reference value for use in human health assessments of foods
Schaefer HR, Flannery BM, Crosby LM, Pouillot R, Farakos SMS, Van Doren JM, Dennis S, Fitzpatrick S, Middleton K. 2023. Reassessment of the cadmium toxicological reference value for use in human health assessments of foods. Regul Toxicol Pharmacol 144(Oct):105487; doi: 10.1016/j.yrtph.2023.105487. PMID: 37640100.
View AbstractRisk assessment of three smoke flavoring primary products currently under re-evaluation by EFSA
Franzen AC, Thompson CM, Brorby GP, Wikoff DS, Ilkbahar Z, Doepker C. Risk assessment of three smoke flavoring primary products currently under re-evaluation by EFSA. Poster presented at Society of Toxicology 62nd Annual Meeting, Nashville, TN, March 2023.
Updated systematic assessment of human, animal and mechanistic evidence demonstrates lack of human carcinogenicity with consumption of aspartame
Borghoff SJ, Cohen SS, Jiang X, Lea IA, Klaren WD, Chappell GA, Britt JK, Rivera BN, Choksi NY, Wikoff DS. 2023. Updated systematic assessment of human, animal and mechanistic evidence demonstrates lack of human carcinogenicity with consumption of aspartame. Food Chem Toxicol 172(Feb):113549; doi: 10.1016/j.fct.2022.113549. PMID: 36493943.
View Abstract2022 (4 POSTS)
Genotypic and phenotypic quantitative microbial risk assessment model of human salmonellosis related to the consumption of chicken meat in the central region of Mexico
Godínez-Oviedo A, Sampedro F, Bowman JP, Garcés-Vega FJ, Hernández-Iturriaga M. 2022. Genotypic and phenotypic quantitative microbial risk assessment model of human salmonellosis related to the consumption of chicken meat in the central region of Mexico. Food Res Int 162(A):111901; doi: 10.1016/j.foodres.2022.111901. PMID: 36461177.
View AbstractOchratoxin A and pesticides in craft beers: A pilot study
Buerger A, Bates C, Boles C, Vincent M, Dotson S. Ochratoxin A and pesticides in craft beers: A pilot study. Poster presentation P193/Abstract 5085, Society of Toxicology 61st Annual Meeting, San Diego, CA. Toxicologist Late-Breaking Supp. 168(1):63, March 2022.
View AbstractMontmorillonite clay-based sorbents decrease the bioavailability of perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) from soil and their translocation to plants
Hearon SE, Orr AA, Moyer H, Wang M, Tamamis P, Phillips TD. Montmorillonite clay-based sorbents decrease the bioavailability of perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) from soil and their translocation to plants. Abstract 3113, Society of Toxicology 61st Annual Meeting, San Diego, CA, March 2022.
View AbstractQuantitative risk assessment model to investigate the public health impact of varying Listeria monocytogenes allowable levels in different food commodities: A retrospective analysis
Sampedro F, Pérez-Rodríguez F, Servadio JL, Gummalla S, Hedberg CW. 2022. Quantitative risk assessment model to investigate the public health impact of varying Listeria monocytogenes allowable levels in different food commodities: A retrospective analysis. Int J Food Microbiol 383(Dec 16):109932 doi: 10.1016/j.ijfoodmicro.2022.109932.
View Abstract2021 (2 POSTS)
Overall lack of genotoxic activity among five common low- and no-calorie sweeteners: A contemporary review of the collective evidence
Lea IA, Chappell GA, Wikoff DS. 2021. Overall lack of genotoxic activity among five common low- and no-calorie sweeteners: A contemporary review of the collective evidence. Mutat Res Genet Toxicol Environ Mutagen 868–869(Aug-Sept):503389; doi: 10.1016/j.mrgentox.2021.503389. PMID: 34454695.
View AbstractAssessing the food safety risk of ochratoxin A in coffee: A toxicology-based approach to food safety planning
Heintz MM, Doepker CL, Wikoff DS, Hawks SE. 2021. Assessing the food safety risk of ochratoxin A in coffee: A toxicology-based approach to food safety planning. J Food Sci 86(11):4799-4810; doi: 10.1111/1750-3841.15938.
View Abstract2020 (4 POSTS)
Microbiota of four tissue types in American alligators (Alligator mississippiensis) following extended dietary selenomethionine exposure
Kieran TJ, Goodman SJ, Finger JW Jr, Thomas JC 4th, Hamilton MT, Tuberville TD, Glenn TC. 2020. Microbiota of four tissue types in American alligators (Alligator mississippiensis) following extended dietary selenomethionine exposure. Bull Environ Contam Toxicol 105(3):381-386; doi: 10.1007/s00128-020-02961-3. PMID: 32794125.
View AbstractEvaluation of potential human health risk associated with consumption of edible products from livestock fed ration supplemented with Red Lake Diatomaceous Earth
Wikoff DS, Bennett DC, Brorby GP, Franke KS. 2020. Evaluation of potential human health risk associated with consumption of edible products from livestock fed ration supplemented with Red Lake Diatomaceous Earth. Food Addit Contam A 37(5):804-814; doi: 10.1080/19440049.2020.1727963. PMID: 32134694.
View AbstractCadmium: Mitigation strategies to reduce dietary exposure
Schaefer HR, Dennis S, Fitzpatrick S. 2020. Cadmium: Mitigation strategies to reduce dietary exposure. J Food Sci 85(2):260-267; doi: 10.1111/1750-3841.14997. PMID: 31957884.
View AbstractLack of potential carcinogenicity for aspartame – Systematic evaluation and integration of mechanistic data into the totality of the evidence
Wikoff DS, Chappell GA, Fitch S, Doepker CL, Borghoff SJ. 2020. Lack of potential carcinogenicity for aspartame – Systematic evaluation and integration of mechanistic data into the totality of the evidence. Food Chem Toxicol 135(Jan):110866; doi: 10.1016/j.fct.2019.110866.
View Abstract2019 (1 POST)
Chemical contaminants in children’s food: A review of recent literature
Schaefer H, Fitzpatrick S, Flannery B. Chemical contaminants in children’s food: A review of recent literature. Abstract 2640, Society of Toxicology 58th Annual Meeting, Baltimore, MD, 2019.
View Abstract2018 (3 POSTS)
Benefit-risk analysis for foods (BRAFO): Evaluation of exposure to dietary nitrates
Wikoff DS, Thompson C, Rager J, Chappell G, Fitch S, Doepker C. 2018. Benefit-risk analysis for foods (BRAFO): Evaluation of exposure to dietary nitrates. Food Chem Toxicol 120:709-723; doi: 10.1016/j.fct.2018.08.031.
View AbstractA systematic approach to identify plausible mode-of-actions (MOA) for an increased incidence of lung tumors in mice with chronic exposure to 4-methylimidazole (4-MEI)
Borghoff S, Wikoff D, Urban JD, Rager JE. A systematic approach to identify plausible mode-of-actions (MOA) for an increased incidence of lung tumors in mice with chronic exposure to 4-methylimidazole (4-MEI). Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.
View AbstractKey findings and implications of a recent systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children
Doepker C, Franke K, Myers E, Goldberger JJ, Lieberman HR, O’Brien C, Peck J, Tenenbein M, Weaver C, Wikoff D. 2018. Key findings and implications of a recent systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children. Nutrients 10(10):1536; doi: 10.3390/nu10101536.
View Abstract2017 (1 POST)
A proposed ADI for nitrate
Doepker D, Tyndall K, Lane R, Wikoff D, Thompson C, Harvey S, Schmitt D. 2017. A proposed ADI for nitrate. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.
View Abstract