Publications

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Published Papers (1146 POSTS)

2025 (33 POSTS)

Evaluation of an anti-thyroid mode of action for thyroid follicular cell adenomas in female mice exposed to tertiary butyl alcohol

Borghoff SJ, Heintz MM, Rivera BN, Haws L, Thompson C. 2025. Evaluation of an anti-thyroid mode of action for thyroid follicular cell adenomas in female mice exposed to tertiary butyl alcohol. Regul Toxicol Pharmacol 105936;  doi: 10.1016/j.yrtph.2025.105936. Online ahead of print Sept. 4, 2025. PMID: 40914479.

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Risk assessment of tire wear in the environment—A literature review

Muller K, Unice K, Panko J, Ferrari BJD, Breider F, Wagner S. 2025. Risk assessment of tire wear in the environment—A literature review. Environ Sci Process Impacts 27(8):2212-2232; doi: 10.1039/d5em00088b. PMID: 40569214.

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AOP 460: Antagonism of Smoothened receptor leading to orofacial clefting

Reynolds JI, Johnson BP. 2025. AOP 460: Antagonism of Smoothened receptor leads to orofacial clefting. ALTEX; doi: 10.14573/altex.2407121. Advance online publication August 11, 2025.

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Why rat oral cavity tumors should not be the basis of quantitative cancer risk assessment for oral exposure to hexavalent chromium

Proctor D, Jiang X, Reichert H, Thompson C. 2025. Why rat oral cavity tumors should not be the basis of quantitative cancer risk assessment for oral exposure to hexavalent chromium. Toxicol Sci kfaf112; doi: 10.1093/toxsci/kfaf112. Online ahead of print August 8, 2025. PMID: 40795394.

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Systematic review of potential developmental and reproductive toxicity of microplastics

Fitch S, Rogers J, Marty S, Norman J, Schneider S, Rushton E, Wikoff D, Ellis-Hutchings R. 2025. Systematic review of potential developmental and reproductive toxicity of microplastics. Toxicol Sci kfaf108; doi: 10.1093/toxsci/kfaf108. Online ahead of print August 5, 2025. PMID: 40794567.

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Human small intestinal tissue models to assess barrier permeability: Comparative analysis of caco-2 cells, jejunal and duodenal enteroid-derived cells, and EpiIntestinalTM tissues in membrane-based cultures with and without flow

Moyer HL, Vergara L, Stephan C, Sakolish C, Lin HC, Chiu WA, Villenave R, Hewitt P, et al. 2025. Human small intestinal tissue models to assess barrier permeability: Comparative analysis of caco-2 cells, jejunal and duodenal enteroid-derived cells, and EpiIntestinalTM tissues in membrane-based cultures with and without flow. Bioengineering (Basel). 12(8):809; doi: 10.3390/bioengineering12080809. PMID: 40868322; PMCID: PMC12384003.

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A systematic literature review of MTAP deletions in solid and hematologic cancers

Clouser MC, Suh M, Movva N, Hildebrand JS, Pastula ST, Schoehl M, Hindoyan A, Balasubramanian A, et al. 2025. A systematic literature review of MTAP deletions in solid and hematologic cancers. Cancer Treat Res Comm 44:100966; doi: 10.1016/j.ctarc.2025.100966. PMID: 40729867.

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Measurement of vinyl acetate monomer in consumer products and modeled estimates of consumer exposure

Gauthier A, Behymer W, Bare J, Kramer M, Barranco WT, Longtin JP, Borghoff S, Jaques A. 2025. Measurement of vinyl acetate monomer in consumer products and modeled estimates of consumer exposure. J Exp Sci Environ Epidemiol; doi: 10.1038/s41370-025-00786-y. Online ahead of print June 18, 2025. PMID: 40533479.

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Tire emissions during the use phase of tires – Current and future trends

Muller K, Unice K, Panko J, Wagner S. 2025. Tire emissions during the use phase of tires – Current and future trends. Environ Sci Adv 4(9):1344-1363; doi: 10.1039/d4va00407h.

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Human health risk assessment of three smoke flavoring primary products

Brorby G, Franzen A, Thompson C, Wikoff D, Doepker C. 2025. Human health risk assessment of three smoke flavoring primary products. Food Chem Toxicol 202(Aug):115490; doi: 10.1016/j.fct.2025.115490. PMID: 40320068.

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Lung cancer risk assessment associated with exposure to hexavalent chromium: Results of pooled analysis of three cohorts

Allen BC, Vincent MJ, Lipworth L, Panko JM, Suh M, Jiang X, Mumma MT, Proctor DM. 2025. Lung cancer risk assessment associated with exposure to hexavalent chromium: Results of pooled analysis of three cohorts. J Occup Environ Hyg; doi: 10.1080/15459624.2025.2502491. Online ahead of print May 28, 2025. PMID: 40435461.

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How to organize a successful toxicology workshop? A participant perspective on the Collaboration to Harmonise the Assessment of Next Generation Evidence (CHANGE) workshop in Oslo, 18-20 June 2024

Diemar MG, Giusti A, Michel-Caillet C, Leme DM, Wikoff D, Bloch D, Sass J, Beekmann K, et al. 2025. How to organize a successful toxicology workshop? A participant perspective on the Collaboration to Harmonise the Assessment of Next Generation Evidence (CHANGE) workshop in Oslo, 18-20 June 2024. Arch Toxicol 99(7):3057-3063; doi: 10.1007/s00204-025-04064-6. PMID: 40372420.

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A real-world analysis of the impact of X-linked myotubular myopathy on caregivers in the United States

Duong T, Haselkorn T, Miller B, Coats J, Jensen I, Ward E, Wood M, Graham RJ, Servais L. 2025. A real-world analysis of the impact of X-linked myotubular myopathy on caregivers in the United States. Orphanet J Rare Dis 20(1):224. doi: 10.1186/s13023-025-03583-w.

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A tool to support food substance safety evaluations in the United States

Crincoli CM, van de Ligt JLG, Eapen AK. Pavel AT, Hanlon PR, Almond-Abbate K, Haugabrooks E,… Henderson RG. 2025. A tool to support food substance safety evaluations in the United States. Regul Toxicol Pharmacol 161(Sept):105838; doi: 10.1016/j.yrtph.2025.105838. PMID: 40324559.

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Reproductive and developmental toxicity screen (OECD TG 421) and extended one generation reproductive toxicity study (OECD TG 443) of decahydronaphthalene in Sprague Dawley rats

Rogers JM, Heintz MM, Haws LC. 2025. Reproductive and developmental toxicity screen (OECD TG 421) and extended one generation reproductive toxicity study (OECD TG 443) of decahydronaphthalene in Sprague Dawley rats. Regul Toxicol Pharmacol 160(Aug):105829; doi: 10.1016/j.yrtph.2025.105829. PMID: 40222475.

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Comparison of phenotypic and transcriptomic profiles between HFPO-DA and prototypical PPARα, PPARγ, and cytotoxic agents in wild-type and Pparα-null mouse livers

Heintz MM, Buerger AN, Haws LC, Cullen JM, East AW, Thompson CM. 2025. Comparison of phenotypic and transcriptomic profiles between HFPO-DA and prototypical PPARα, PPARγ, and cytotoxic agents in wild-type and Pparα-null mouse livers. Toxicol Sci 206(1):183-201; doi: 10.1093/toxsci/kfaf049. PMID: 40216583.

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Rethinking systematic review assignment design in graduate health science education from librarians’ perspectives

Lipke L, Price C. 2025. Rethinking systematic review assignment design in graduate health science education from librarians’ perspectives. Hypoth: Res J Health Info Prof 37(1); doi: 10.18060/28463.

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Application of a quantitative uncertainty assessment to develop ranges of plausible toxicity values when using observational data in risk assessment: A case study examining associations between PFOA and PFOS exposures and vaccine response

Wikoff DS, Vincent MJ, Heintz MM, Pastula ST, Reichert H, Klaren WD, Haws LC. 2025. Application of a quantitative uncertainty assessment to develop ranges of plausible toxicity values when using observational data in risk assessment: A case study examining associations between PFOA and PFOS exposures and vaccine response. Toxicol Sci 204(1):96-115; doi: 10.1093/toxsci/kfae152. PMID: 39792025.

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Evaluation of the endocrine disrupting potential of Di-isodecyl phthalate

Lea IA, Feifarek D, Mihalchik A, Heintz M, Haws L, Nyambego H, Goyak K, Palermo C, Borghoff SJ. 2025. Evaluation of the endocrine disrupting potential of Di-isodecyl phthalate. Curr Res Toxicol 8:100221; doi: 10.1016/j.crtox.2025.100221. PMID: 40041033.

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Analysis of EPA air toxics monitoring data and tools for use in general population exposure assessments: Using acrylonitrile as a case study

Kramer A, Vivanco S, Bare J, Panko J. 2025. Analysis of EPA air toxics monitoring data and tools for use in general population exposure assessments: Using acrylonitrile as a case study. J Air Waste Manag Assoc 75(3)181-197; doi: 10.1080/10962247.2024.2438793. PMID: 39660961.

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