Publications

Manganese (11 POSTS)

2024 (3 POSTS)

PBPK modeling demonstrates that exposure time adjustment is unnecessary for setting an acute manganese inhalation exposure guideline

Perry CS, Verwiel AH, Covington TR, Proctor DM. 2024. PBPK modeling demonstrates that exposure time adjustment is unnecessary for setting an acute manganese inhalation exposure guideline. Regul Toxicol Pharmacol 153(Nov):105698; doi: 10.1016/j.yrtph.2024.105698. PMID: 39251127.

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Probabilistic risk assessment of residential exposure to electric arc furnace steel slag using Bayesian model of relative bioavailability and PBPK modeling of manganese

Mittal L, Perry CS, Blanchette AD, Proctor DM. 2024. Probabilistic risk assessment of residential exposure to electric arc furnace steel slag using Bayesian model of relative bioavailability and PBPK modeling of manganese. Risk Anal. 44(9):2169-2186. doi: 10.1111/risa.14309. PMID: 38622492.

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Derivation of manganese 24-hour acute inhalation guideline protective of respiratory and neurological effects

Perry CS, Vivanco SN, Verwiel AH, Proctor DM. Derivation of manganese 24-hour acute inhalation guideline protective of respiratory and neurological effects. Abstract 4751, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024.

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2023 (1 POST)

Use of physiologically based pharmacokinetic modeling to support development of an acute (24-hour) health-based inhalation guideline for manganese

Perry CS, Blanchette AD, Vivanco SN, Verwiel AH, Proctor DM. 2023. Use of physiologically based pharmacokinetic modeling to support development of an acute (24-hour) health-based inhalation guideline for manganese. Regul Toxicol Pharmacol 145:105518; doi: 10.1016/j.yrtph.2023.105518. PMID: 3786341.

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2022 (2 POSTS)

Short-term environmental inhalation toxicity criteria for airborne manganese protective of neurological and respiratory effects for use in air toxics risk assessment

Perry C, Proctor D. Short-term environmental inhalation toxicity criteria for airborne manganese protective of neurological and respiratory effects for use in air toxics risk assessment. Presentation 5-15.T-04 to Society of Environmental Toxicology and Chemistry, Pittsburgh PA, November 2022.

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Refined health risk assessment for residential exposures to manganese in EAF steel slag

Proctor DM, Antonijevic T. Refined health risk assessment for residential exposures to manganese in EAF steel slag. Poster presented at Society of Toxicology 61st Annual Meeting, San Diego, CA, March 2022.

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2019 (1 POST)

Assessing children’s exposure to manganese in drinking water using a PBPK model

Yoon M, Ring C, Van Landingham CB, Suh M, Song G, Antonijevic T, Gentry PR, Taylor MD, Keen AM, Andersen ME, Clewell JH. 2019. Assessing children’s exposure to manganese in drinking water using a PBPK model. Toxicol Appl Pharmacol 380(Oct 1):114695; doi: 10.1016/j.taap.2019.114695.

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2016 (1 POST)

Dietary manganese modulates PCB126 toxicity, metal status and MnSOD in the rat

Wang BW, Klaren WD, Wels B, Simmons DL, Olivier AK, Wang K, Robertson LW, Ludewig G. 2016. Dietary manganese modulates PCB126 toxicity, metal status and MnSOD in the rat. Toxicol Sci 150(1):15–26; doi: 10.1093/toxsci/kfv312. PMID: 26660635.

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2015 (1 POST)

Welding and occupational exposure to manganese fumes and Parkinson’s disease: An evidence-based causation analysis

Britt J, James R. 2015. Welding and occupational exposure to manganese fumes and Parkinson’s disease: An evidence-based causation analysis. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

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2012 (1 POST)

Regulation of MnSOD by the AhR agonist PCB126: The role of dietary manganese

Wang B, Wels BR, Klaren WD, Wang K, Robertson LW, Ludewig G. Regulation of MnSOD by the AhR agonist PCB126: The role of dietary manganese. Society of Toxicology 51st Annual Meeting, San Francisco, Ca, 2012. Also presented at Superfund Annual Meeting, Lexington, Ky, 2012.

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1996 (1 POST)

Developing physiologically-based pharmacokinetic (PB-PK) models for manganese and iron

Covington TR, Clewell HJ III, Gearhart JM, Andersen ME. Developing physiologically-based pharmacokinetic (PB-PK) models for manganese and iron. Poster presented at the Society of Toxicology Annual Meeting, Anaheim, CA, March 1996.