Publications

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Jonathan D. Urban (48 POSTS)

2024 (2 POSTS)

Dioxin-like compounds in soils: A pilot survey updating background soil TEQ

Urban JD, Covington TR, Fitch SE, Wikoff DS. Dioxin-like compounds in soils: A pilot survey updating background soil TEQ. Abstract 5147, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024. 

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Development and application of systematic approach to inventory and interrogate thyroid hormone network information

Lynn SG, Lea IA, Urban J, Borghoff SJ, Wikoff D, Fitch S, Perry C, Choksi N, Britt J, Heintz M, Klaren W, et al. Development and application of systematic approach to inventory and interrogate thyroid hormone network information. Abstract 4357, Society of Toxicology 63rd Annual Meeting, Salt Lake City, UT, March 2024. 

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2021 (1 POST)

Development of a range of plausible non-cancer toxicity values for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) based on effects on sperm count: Application of systematic review methods and quantitative integration of dose response using meta-regression

Wikoff DS, Urban JD, Ring C, Britt J, Fitch S, Haws LC. 2021. Development of a range of plausible non-cancer toxicity values for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) based on effects on sperm count: Application of systematic review methods and quantitative integration of dose response using meta-regression. Toxicol Sci 179(2):162-182; doi: 10.1093/toxsci/kfaa171.

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2020 (1 POST)

Systematic evaluation of mechanistic data in assessing in utero exposures to trichloroethylene and development of congenital heart defects

Urban JD, Wikoff DS, Chappell GA, Harris C, Haws LC. 2020. Systematic evaluation of mechanistic data in assessing in utero exposures to trichloroethylene and development of congenital heart defects. Toxicology 436(30 April):152427; doi: 10.1016/j.tox.2020.152427. PMID: 32145346.

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2019 (1 POST)

Application of systematic review and quantitative evidence integration methods to support risk assessment: Characterization of the dose-response relationship between exposure to dioxin-like compounds (DLC) and sperm count

Ring CL, Urban J, Wikoff D, Thompson C, Budinsky RA, Haws LC. Application of systematic review and quantitative evidence integration methods to support risk assessment: Characterization of the dose-response relationship between exposure to dioxin-like compounds (DLC) and sperm count. Poster at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.

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2018 (3 POSTS)

Systematic review and meta-regression to characterize the dose-response relationship between exposure to dioxin-like compounds during sensitive windows of development and reduced sperm count

Urban J, Wikoff D, Haws L, Fitch S, Ring C, Thompson C, Suh M. 2018. Systematic review protocol: Systematic review and meta-regression to characterize the dose-response relationship between exposure to dioxin-like compounds during sensitive windows of development and reduced sperm count. Zenodo. http://doi.org/10.5281/zenodo.1636357.

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A systematic approach to identify plausible mode-of-actions (MOA) for an increased incidence of lung tumors in mice with chronic exposure to 4-methylimidazole (4-MEI)

Borghoff S, Wikoff D, Urban JD, Rager JE. A systematic approach to identify plausible mode-of-actions (MOA) for an increased incidence of lung tumors in mice with chronic exposure to 4-methylimidazole (4-MEI). Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.

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Role of risk of bias in systematic review for chemical risk assessment: A case study in understanding the relationship between congenital heart defects and exposures to trichloroethylene

Wikoff D, Urban JD, Harvey S, Haws LC. 2018. Role of risk of bias in systematic review for chemical risk assessment: A case study in understanding the relationship between congenital heart defects and exposures to trichloroethylene. Int J Toxicol 37(2):125-143; doi: 10.1177/1091581818754330.

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2015 (2 POSTS)

A state of the science copper reference dose for soil remediation

Urban JD, Thompson CM, Plunkett LM, Perry CS, Haws LC. A state of the science copper reference dose for soil remediation. Presented at Society of Toxicology 54th Annual Meeting, San Diego, CA, March 2015.

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Steviol glycoside safety: Are highly purified steviol glycoside sweeteners food allergens?

Urban JD, Carakostas MC, Taylor SL. 2015. Steviol glycoside safety: Are highly purified steviol glycoside sweeteners food allergens? Food Chem Toxicol 75(Jan):71-78; doi: 10.1016/j.fct.2014.11.011.

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2014 (3 POSTS)

Do highly purified steviol glycoside sweeteners cause food allergies?

Urban JD, Doepker CL, Cuellar-Kingston N, van de Ligt J, Carakostas M. Do highly purified steviol glycoside sweeteners cause food allergies? Presented at Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.

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Evaluation of impact of shale gas operations in the Barnett Shale region on volatile organic compounds in air and potential human health risks

Bunch AG, Perry CS, Abraham L, Wikoff DS, Tachovsky JA, Hixon JG, Urban JD, Harris MA, Haws LC. 2014. Evaluation of impact of shale gas operations in the Barnett Shale region on volatile organic compounds in air and potential human health risks. Sci Tot Environ 468-469(Jan 15):832-842; doi: 10.1016/j.scitotenv.2013.08.080. PMID: 24076504.

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A review of background dioxin concentrations in urban/suburban and rural soils across the United States: Implications for site assessments and the establishment of soil cleanup levels

Urban JD, Wikoff DS, Bunch ATG, Harris MA, Haws LC. 2014. A review of background dioxin concentrations in urban/suburban and rural soils across the United States: Implications for site assessments and the establishment of soil cleanup levels. Sci Tot Environ 466-467:(Jan 1)586-597; doi: 10.1016/j.scitotenv.2013.07.065.

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2013 (2 POSTS)

A genomics-based analysis of relative potencies of dioxin-like compounds in primary rat hepatocytes

Rowlands JC, Budinsky R, Gollapudi B, Black MB, Wolfinger RD, Cukovic D, Bombkowski A, Thompson CM, Urban JD, Thomas RS. 2013. A genomics-based analysis of relative potencies of dioxin-like compounds in primary rat hepatocytes. Toxicol Sci 136(2):595-604; doi: 10.1093/toxsci/kft203.

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Steviol glycoside safety: Is the genotoxicity database sufficient?

Urban JD, Carakostas MC, Brusick DJ. 2013. Steviol glycoside safety: Is the genotoxicity database sufficient? Food Chem Toxicol 51(Jan):386-390; doi: 10.1016/j.fct.2012.10.016.

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2012 (5 POSTS)

Assessment of genotoxic potential of Cr(VI) in the mouse duodenum: An in silico comparison with mutagenic and nonmutagenic carcinogens across tissues

Thompson CM, Hixon JG, Proctor DM, Haws LC, Suh M, Urban JD, Harris MA. 2012. Assessment of genotoxic potential of Cr(VI) in the mouse duodenum: An in silico comparison with mutagenic and nonmutagenic carcinogens across tissues. Regul Toxicol Pharmacol 64(1):68-76; doi: 10.1016/j.yrtph.2012.05.019

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Receptor conformations involved in dopamine D2L receptor functional selectivity induced by selected transmembrane 5 serine mutations

Fowler, JC, Bhattacharya S, Urban JD, Vaidehi N, Mailman RB. 2012. Receptor conformations involved in dopamine D2L receptor functional selectivity induced by selected transmembrane 5 serine mutations. Mol Pharmacol 81(6):820-831; doi: 10.1124/mol.111.075457.

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Natural gas exploration and production in the Barnett Shale: Assessment of exposures to volatile organic compounds (VOCs)

Perry C, Tachovsky JA, Ke M, Urban J, Haws L. Natural gas exploration and production in the Barnett Shale: Assessment of exposures to volatile organic compounds (VOCs). Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.

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An evaluation of single nucleotide polymorphisms in the human heat shock protein 90kDa alpha and beta isoforms

Urban J, Budinsky R, Rowlands J. 2012. An evaluation of single nucleotide polymorphisms in the human heat shock protein 90kDa alpha and beta isoforms. Drug Metab Pharmacokinet 27(2):268-278; doi: 10.2133/dmpk.DMPK-11-SC-114.

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A genomics-based benchmark dose analyses of relative potencies of dioxin-like compounds in primary rat hepatocytes

Urban J, Rowlands JC, Budinsky R, Dombkowski A, Thompson CM, Thomas RS. A genomics-based benchmark dose analyses of relative potencies of dioxin-like compounds in primary rat hepatocytes. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.

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