Published Papers (1146 POSTS)

2016 (61 POSTS)

Differential pulmonary effects of CoO and La2O3 metal oxide nanoparticle responses during aerosolized inhalation in mice

Sisler JD, Li R, McKinney W, Mercer RR, Ji Z, Xia T, Wang X, Shaffer J, Orandle M, Mihalchik AL, Battelli L. 2016. Differential pulmonary effects of CoO and La2O3 metal oxide nanoparticle responses during aerosolized inhalation in mice. Particle Fibre Toxicol 13(1):42; doi: 10.1186/s12989-016-0155-3.

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Toxicological assessment of CoO and La2O3 metal oxide nanoparticles in human small airway epithelial cells

Sisler JD, Pirela SV, Shaffer J, Mihalchik AL, Chisholm WP, Andrew ME, Schwegler-Berry D, Castranova V, et al. 2016. Toxicological assessment of CoO and La2O3 metal oxide nanoparticles in human small airway epithelial cells. Toxicol Sci 150(2):418-428; doi: 10.1093/toxsci/kfw005.

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2015 (41 POSTS)

Inhalation cancer risk assessment of hexavalent chromium based on updated mortality for Painesville chromate production workers

Proctor DM, Suh M, Mittal L, Hirsch S, Salgado RV, Bartlett C, Van Landingham C, Rohr A, Crump K. 2015. Inhalation cancer risk assessment of hexavalent chromium based on updated mortality for Painesville chromate production workers. J Expo Sci Environ Epidemiol 26(2):224-231. doi: 10.1038/jes.2015.77.

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Measured removal rates of chrysotile asbestos fibers from air and comparison with theoretical estimates based on gravitational settling and dilution ventilation

Sahmel J, Avens HJ, Scott PK, Unice K, Burns A, Barlow CA, Madl AK, Henshaw J, Paustenbach DJ. 2015. Measured removal rates of chrysotile asbestos fibers from air and comparison with theoretical estimates based on gravitational settling and dilution ventilation. Inhal Toxicol 27(14):787-801; doi: 10.3109/08958378.2015.1110216. PMID: 26671197.

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Atrazine exposure and reproductive dysfunction through the hypothalamus-pituitary-gonadal (HPG) axis

Wirbisky SE, Freeman JL. 2015. Atrazine exposure and reproductive dysfunction through the hypothalamus-pituitary-gonadal (HPG) axis. Toxics 3:414–450; doi: 10.3390/toxics3040414.

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Toxicology of wear particles of cobalt-chromium alloy metal-on-metal hip implants Part II: Importance of physiochemical properties and dose in animal and in vitro studies as a basis for risk assessment

Madl AK, Kovochich M, Liong M, Finley BL, Paustenbach DJ, Oberdorster G. 2015. Toxicology of wear particles of cobalt-chromium alloy metal-on-metal hip implants Part II: Importance of physiochemical properties and dose in animal and in vitro studies as a basis for risk assessment. Nanomed: Nanotech Biol Med 11(5):1285–1298; doi: 10.1016/j.nano.2015.02.006. PMID: 25735266.

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Evidence-based causation in toxicology: A 10-year retrospective

James RC, Britt JK, Halmes NC, Guzelian PS. 2015. Evidence-based causation in toxicology: A 10-year retrospective. Hum Exp Toxicol 34(12):1245–1252; doi: 10.1177/0960327115601767.

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Historical context and recent advances in exposure-response estimation for deriving occupational exposure limits

Wheeler MW, Park R, Bailer A, Whittaker C. 2015. Historical context and recent advances in exposure-response estimation for deriving occupational exposure limits. J Occup Environ Hyg 12(sup1):S7-S17; doi: 10.1080/15459624.2015.1076934. PMCID: PMC4685605.

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Acute lymphoblastic leukemia: An assessment of international incidence, survival, and disease burden

Katz AJ, Chia VM, Schoonen WM, Kelsh MA. 2015. Acute lymphoblastic leukemia: An assessment of international incidence, survival, and disease burden. Cancer Causes Control 26(11):1627–1642.

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Real-time monitoring and assessment of thermal and toxicological risk associated with fire retardant textiles in a full-size simulation of an engulfment flash fire

Mackay CE, Vivanco SN, Reinhardt TE, McClure S, Vercellone J. 2015. Real-time monitoring and assessment of thermal and toxicological risk associated with fire retardant textiles in a full-size simulation of an engulfment flash fire. Fire Technol 51(5):1167–1193; doi: 10.1007/s10694-015-0456-3.

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Quantile benchmark dose estimation for continuous endpoints

Wheeler MW, Shao K, Bailer AJ. 2015. Quantile benchmark dose estimation for continuous endpoints. Environmetrics 26(5):363-72; doi: 10.1002/env.2432.

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Duodenal crypt health following exposure to Cr(VI): Micronucleus scoring, γ-H2AX immunostaining, and synchrotron x-ray fluorescence microscopy

Thompson CM, Wolf JC, Elbekai RH, Paranjpe MG, Seiter JM, Chappell MA, Tappero RV, Suh M, Proctor DM, Bichteler A, Haws LC, Harris MA. 2015. Duodenal crypt health following exposure to Cr(VI): Micronucleus scoring, γ-H2AX immunostaining, and synchrotron x-ray fluorescence microscopy. Mut Res 789–790:61–66; doi: 10.1016/j.mrgentox.2015.05.004.

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Developmental origins of neurotransmitter and transcriptome alterations in adult female zebrafish exposed to atrazine during embryogenesis

Wirbisky SE, Weber GJ, Sepúlveda MS, Xiao C, Cannon JR, Freeman JL. 2015. Developmental origins of neurotransmitter and transcriptome alterations in adult female zebrafish exposed to atrazine during embryogenesis. Toxicology 333:156–167.

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Progression of micronutrient alteration and hepatotoxicity following acute exposure to PCB126

Klaren WD, Gadupudi GS, Wels B, Simmons DL, Olivier AK, Ludewig G, Robertson LW. 2015. Progression of micronutrient alteration and hepatotoxicity following acute exposure to PCB126. Toxicol 338(Dec):1–7; doi: 10.1016/j.tox.2015.09.004. PMID: 26410179.

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PCB126-induced disruption in gluconeogenesis and fatty acid oxidation precedes fatty liver in male rats

Gadupudi GS, Klaren WD, Olivier AK, Klingelhutz AJ, Robertson LW. PCB126-induced disruption in gluconeogenesis and fatty acid oxidation precedes fatty liver in male rats. Superfund Annual Meeting, San Juan, Puerto Rico, 2015.

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Chemical assessment state of the science: Evaluation of 32 decision-support tools used to screen and prioritize chemicals

Gauthier AM, Fung M, Panko J, Kingsbury T, Perez AL, Hitchcock K, Ferracini T, Sahmel J, Banducci A, Jacobsen M, Abelmann A, Shay E. 2015. Chemical assessment state of the science: Evaluation of 32 decision-support tools used to screen and prioritize chemicals. Integr Environ Assess Manag 11(2):242–255; doi: 10.1002/ieam.1605.

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Evaluation of quantitative exposure assessment method for nanomaterials in mixed dust environments: Application in tire manufacturing facilities

Kreider ML, Cyrs WD, Tosiano MA, Panko JM. 2015. Evaluation of quantitative exposure assessment method for nanomaterials in mixed dust environments: Application in tire manufacturing facilities. Ann Occup Hyg 59(9):1122–1134; doi: 10.1093/annhyg/mev052.

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Assessment of the mutagenic potential of Cr(VI) in the oral mucosa of Big Blue® transgenic F344 rats

Thompson CM, Young RR, Suh M, Dinesdurage HR, Elbekai RH, Harris MA, Rohr AC, Proctor DM. 2015. Assessment of the mutagenic potential of Cr(VI) in the oral mucosa of Big Blue® transgenic F344 rats. Environ Mol Mutagen 56(7):621-628; doi: 10.1002/em.21952.

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A hospital budget impact model to evaluate plerixafor in stem cell mobilization: Impact of primary research and direct stakeholder engagemen

Jensen I, Halbert R, Giuseppe R, Naoshy S, Iqbal SU, Zhimin X, McSweeney P. 2015. A hospital budget impact model to evaluate plerixafor in stem cell mobilization: Impact of primary research and direct stakeholder engagement. Eur J Hosp Pharm 22(3):142–149; doi: 10.1136/ejhpharm-2014-000543.

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Design of potent and orally active GPR119 agonists for the treatment of type II diabetes

Liu P, Hu Z, DuBois BG, Moyes CR, Hunter DN, Zhu C, … Dingley KH, et al. 2015. Design of potent and orally active GPR119 agonists for the treatment of type II diabetes. ACS Med Chem Lett 6(8):936–941; doi: 10.1021/acsmedchemlett.5b00207. PMID: 26288697.

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