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cobalt (23 POSTS)

2020 (1 POST)

Oral and inhalation bioaccessibility of cobalt and nickel in metal alloys: A critical consideration for site-specific human health risk assessments and read across

Suh M, Verwiel A, Proctor D. Oral and inhalation bioaccessibility of cobalt and nickel in metal alloys: A critical consideration for site-specific human health risk assessments and read across. Poster for Society of Toxicology 59th Annual Meeting, Virtual, 2020.

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2019 (1 POST)

Bioaccessibility and relative oral bioavailability of cobalt and nickel in residential soil and dust affected by metal grinding operations

Suh M, Casteel S, Dunsmore M, Ring C, Verwiel A, Proctor DM. 2019. Bioaccessibility and relative oral bioavailability of cobalt and nickel in residential soil and dust affected by metal grinding operations. Sci Tot Environ 660(April 10):677–689; doi: 10.1016/j.scitotenv.2018.12.317.

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2018 (1 POST)

Relative oral bioavailability of cobalt and nickel in residential soil and dust affected by metal grinding operations

Ring CL, Suh M, Casteel S, Dunsmore M, Verwiel A, Proctor D. Relative oral bioavailability of cobalt and nickel in residential soil and dust affected by metal grinding operations. Presented at Joint Annual Meeting of International Society of Exposure Science and International Society for Environmental Epidemiology (ISES-ISEE 2018), Ottawa, Canada, August 2018.

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2017 (2 POSTS)

Characteristics of cobalt related cardiomyopathy in metal hip implant patients

Fung ES, Monnot AD, Tvermoes BE, Unice KM, Kovochich M, Galbraith DA, Finley BL, Paustenbach DJ. Characteristics of cobalt related cardiomyopathy in metal hip implant patients. Abstract #2142. Poster presentation at Society of Toxicology 56th Annual Meeting, Baltimore, MD, 2017.

Bioaccessibility and relative oral bioavailability of cobalt and nickel from metal alloys in soil and dust

Proctor DM, Suh M, Dunsmore D, Verwiel A, Casteel S. Bioaccessibility and relative oral bioavailability of cobalt and nickel from metal alloys in soil and dust. Poster presented at Society of Toxicology 56th Annual Meeting, Baltimore, MD, March 2017.

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2016 (2 POSTS)

Inhalation cancer risk assessment of cobalt metal

Suh M, Thompson CM, Brorby GP, Mittal L, Proctor DM. 2016. Inhalation cancer risk assessment of cobalt metal. Regul Toxicol Pharm 79(Aug):74-82; doi: 10.1016/j.yrtph.2016.05.009.

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Inhalation cancer risk assessment of cobalt metal

Brorby GP, Suh M, Thompson CM, Mittal L, Proctor DM. Inhalation cancer risk assessment of cobalt metal. Presented at Society of Toxicology 55th Annual Meeting, New Orleans, LA, March 2016.

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2015 (4 POSTS)

Toxicology of wear particles of cobalt-chromium alloy metal-on-metal hip implants Part II: Importance of physiochemical properties and dose in animal and in vitro studies as a basis for risk assessment

Madl AK, Kovochich M, Liong M, Finley BL, Paustenbach DJ, Oberdorster G. 2015. Toxicology of wear particles of cobalt-chromium alloy metal-on-metal hip implants Part II: Importance of physiochemical properties and dose in animal and in vitro studies as a basis for risk assessment. Nanomed: Nanotech Biol Med 11(5):1285–1298; doi: 10.1016/j.nano.2015.02.006. PMID: 25735266.

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Review of cobalt toxicokinetics following oral dosing: Implications for health risk assessments and metal-on-metal hip implant patients

Tvermoes BE, Paustenbach DJ, Kerger BD, Finley BL, Unice KM. 2015. Review of cobalt toxicokinetics following oral dosing: Implications for health risk assessments and metal-on-metal hip implant patients. Crit Rev Toxicol 45(5):367–387.

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Toxicology of wear particles of cobalt-chromium alloy metal-on-metal hip implants Part I: Physiochemical properties in patient and simulator studies

Madl AK, Liong M, Kovochich M, Finley BL, Paustenbach DJ, Oberdorster G. 2015. Toxicology of wear particles of cobalt-chromium alloy metal-on-metal hip implants Part I: Physiochemical properties in patient and simulator studies. Nanomed: Nanotechnol Biol Med 11(5):1201–1215; doi: 10.1016/j.nano.2015.02.006.

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Toxicology based cancer causation analysis of COCR-containing hip implants: A quantitative assessment of genotoxicity and tumorigenicity studies

Christian WV, Oliver LD, Paustenbach DJ, Kreider ML, Finley BL. Toxicology based cancer causation analysis of COCR-containing hip implants: A quantitative assessment of genotoxicity and tumorigenicity studies. Poster presentation at Society of Toxicology 54th Annual Meeting, San Diego, CA, 2015.

2014 (4 POSTS)

Letter to the Editor: Authors’ response to letters to the editor re: Interpreting cobalt blood concentrations in hip implant patients

Paustenbach D, Galbraith D, Finley B. 2014. Letter to the Editor: Authors’ response to letters to the editor re: Interpreting cobalt blood concentrations in hip implant patients. Clin Toxicol 52(5):569–570.

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Interpreting cobalt blood concentrations in hip implant patients

Paustenbach DJ, Galbraith DA, Finley BL. 2014. Interpreting cobalt blood concentrations in hip implant patients. Clin Toxicol 52(2):98–112; doi: 10.3109/15563650.2013.857024. PMID: 24256093.

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Refined biokinetic model for humans exposed to cobalt dietary supplements and other sources of systemic cobalt exposure

Unice KM, Kerger BD, Paustenbach DJ, Finley BL, Tvermoes BE. 2014. Refined biokinetic model for humans exposed to cobalt dietary supplements and other sources of systemic cobalt exposure. Chem-Biol Interact 216:53–74; doi: 10.1016/j.cbi.2014.04.001. PMID: 24726710.

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Effects and blood concentrations of cobalt after ingestion of 1 mg/d by human volunteers for 90 d1-3

Tvermoes BE, Unice KM, Paustenbach DJ, Finley BL, Otani JM, Galbraith DA. 2014. Effects and blood concentrations of cobalt after ingestion of 1 mg/d by human volunteers for 90 d1-3. Am J Clin Nutr 99(3):632–646; doi: 10.3945/ajcn.113.071449. PMID: 24500148.

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2013 (5 POSTS)

Cobalt whole blood concentrations in healthy adult male volunteers following two-weeks of ingesting a cobalt supplement

Tvermoes BE, Finley BL, Unice KM, Otani JM, Paustenbach DJ, Galbraith DA. 2013. Cobalt whole blood concentrations in healthy adult male volunteers following two-weeks of ingesting a cobalt supplement. Food Chem Toxicol 53:432–439; doi: 10.1016/j.fct.2012.11.033. PMID: 23207477.

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A review of the health hazards posed by cobalt

Paustenbach DJ, Tvermoes BE, Unice KM, Finley BL, Kerger BD. 2013. A review of the health hazards posed by cobalt. Crit Rev Toxicol 43(4):316–362; doi:10.3109/10408444.2013.779633. PMID: 23656559.

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Cobalt speciation assay for human serum, Part II. Method validation in a study of human volunteers ingesting cobalt (II) chloride dietary supplement for 90 days

Kerger BD, Tvermoes BE, Unice KM, Finley BL, Paustenbach DJ, Galbraith DA. 2013. Cobalt speciation assay for human serum, Part II. Method validation in a study of human volunteers ingesting cobalt (II) chloride dietary supplement for 90 days. Toxicol Environ Chem 95(4):709–718; doi: 10.1080/02772248.2013.792559.

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Cobalt speciation assay for human serum, Part I. Method for measuring large and small molecular cobalt and protein-binding capacity using size exclusion chromatography with inductively-coupled plasma-mass spectroscopy detection

Kerger BD, Gerads R, Gurleyuk H, Thuett KA, Finley BL, Paustenbach DJ. 2013. Cobalt speciation assay for human serum, Part I. Method for measuring large and small molecular cobalt and protein-binding capacity using size exclusion chromatography with inductively-coupled plasma-mass spectroscopy detection. Toxicol Environ Chem 95(4):687–708; doi: 10.1080/02772248.2013.793444.

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31-day study of cobalt (II) chloride ingestion in humans: Pharmacokinetics and clinical effects

Finley BL, Unice KM, Kerger BD, Otani JM, Paustenbach DJ, Galbraith DA, Tvermoes BE. 2013. 31-day study of cobalt (II) chloride ingestion in humans: Pharmacokinetics and clinical effects. J Toxicol Environ Health A, 76:1210–1224; doi: 10.1080/15287394.2013.848391. PMID: 24283372.

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