Publications

Transcriptomic analysis of the differential nephrotoxicity of diverse brominated flame retardants in rat and human renal cells

Barnett LMA, Kramer NE, Buerger AN, Love DH, Bisesi JH, Cummings BS. 2021. Transcriptomic analysis of the differential nephrotoxicity of diverse brominated flame retardants in rat and human renal cells. Int J Mol Sci 22(18):10044; doi: 10.3390/ijms221810044. PMID: 34576211.

The use of apnea test and brain death determination in patients on extracorporeal membrane oxygenation: A systematic review.

Migdady I, Stephens RS, Price C, Geocadin RG, Whitman G, Cho SM. 2021. The use of apnea test and brain death determination in patients on extracorporeal membrane oxygenation: A systematic review. J Thorac Cardiovasc Surg 162(3):P867-P877; https://doi.org/10.1016/j.jtcvs.2020.03.038.

Bayesian joint modeling of chemical structure and dose response curves

Moran KR, Dunson D, Wheeler MW, Herring AH. 2021. Bayesian joint modeling of chemical structure and dose response curves. Ann Appl Stat 15(3):1405; doi: 10.214/21-aoas1461. PMCID: PMC9236276.

Effectiveness and safety of romiplostim among patients with newly diagnosed, persistent and chronic immune thrombocytopenia in European clinical practice

Lessons learned using real-world data to emulate randomized trials: A case study of treatment effectiveness for newly diagnosed immune thrombocytopenia

McGrath LJ, Nielson C, Saul B, Breskin A, Yu Y, Nicolaisen SK, … Kelsh M, et al. 2021. Lessons learned using real-world data to emulate randomized trials: A case study of treatment effectiveness for newly diagnosed immune thrombocytopenia. Clin Pharmacol Ther 110(6):1570–1578; doi: 10.1002/cpt.2399. PMID: 34416023.

The impact of increasing multitarget stool DNA use among colorectal cancer screeners in a self-insured US employer population

Hathway J, Miller-Wilson L, Sharma A, Jensen I, Yao W, Raza S, et al. 2021. The impact of increasing multitarget stool DNA use among colorectal cancer screeners in a self-insured US employer population. J Mark Access Health Policy, 9(1):1948670; doi: 10.1080/20016689.2021.1948670.

Respiratory virus surveillance in infants across different clinical settings

Haddadin Z, Rankin DA, Lipworth L, Suh M, McHenry R, Blozinski A, Salib George S, Fernandez KN, Varjabedian R, Spieker AJ, Shepard DS, Halasa NB. 2021. Respiratory virus surveillance in infants across different clinical settings. J Pediat 234(July):p164-p171; doi: 10.1016/j.jpeds.2021.03.036.

Healthcare resource utilization among patients with cold agglutinin disease in Denmark

Vágó EK, Nicholson G, Horváth-Puhó E. Hooda N, Fryzek JP, Su J. 2021. Healthcare resource utilization among patients with cold agglutinin disease in Denmark. Curr Med Res Opin 37(10):1829-1835; doi: 10.1080/03007995.2021.1960494.

Appropriate in vivo follow-up assays to an in vitro bacterial reverse mutation (Ames) test positive investigational drug candidate (active pharmaceutical ingredient), drug- related metabolite, or drug-related impurity

Robison TW, Heflich RH, Manjanatha MG, Elespuru R, Atrakchi A, Mei N, Ding W. 2021. Appropriate in vivo follow-up assays to an in vitro bacterial reverse mutation (Ames) test positive investigational drug candidate (active pharmaceutical ingredient), drug- related metabolite, or drug-related impurity. Mutat Res Gen Toxicol Environ Mutagen 868-869:503386; doi: 10.1016/j.mrgentox.2021.503386.

Costs and health resource use in patients with X-linked myotubular myopathy: insights from U.S. commercial claims

Review of potential risks associated with supplementary dietary exposure to nitrate-containing compounds in swine — A paradox in light of emerging benefits

Doepker CD, Heintz MM, van de Ligt JLG, Wikoff DS. 2021. Review of potential risks associated with supplementary dietary exposure to nitrate-containing compounds in swine — A paradox in light of emerging benefits. Trans Anim Sci 5(4):txab203; doi: 10.1093/tas/txab203. PMID: 34909600.

Impact of calcium nitrate supplementation on the oxygen-carrying capacity of lactating sows and their offspring

van de Ligt JLG, Saddoris-Clemens KL, Norton SA, Davis MD, Doepker CL. 2021. Impact of calcium nitrate supplementation on the oxygen-carrying capacity of lactating sows and their offspring. Trans Anim Sci 5(4):txab217; doi: 10.1093/tas/txab217.

The Residential Population Generator (RPGen): Parameterization of residential, demographic, and physiological data to model intraindividual exposure, dose, and risk

East A, Dawson D, Glen G, Isaacs K, Dionisio K, Price PS, et al. 2021. The Residential Population Generator (RPGen): Parameterization of residential, demographic, and physiological data to model intraindividual exposure, dose, and risk. Toxics 9(11):303; doi: 10.3390/toxics9110303.

Derivation of an occupational exposure limit for β-glucans

Parker JA, Boles C, Buerger AN, Fung ES, Maier A. 2021. Derivation of an occupational exposure limit for β-glucans. Regul Toxicol Pharmacol 123(July):104959; doi: 10.1016/j.yrtph.2021.104959. PMID: 34019963.

Mutational signatures in T-lymphocytes of rats treated with N-propyl-N-nitrosourea and procarbazine

Revollo JR, McKinzie PB, Robison TW, Dobrovolsky VN. 2021. Mutational signatures in T-lymphocytes of rats treated with N-propyl-N-nitrosourea and procarbazine. Environ Mol Mutagen 62(6):350-363; doi: 10.1002/em.22448.

Mercapturate pathway metabolites of sotorasib, a covalent inhibitor of KRASG12C, are associated with renal toxicity in the Sprague Dawley rat

Werner JA, Davies R, Wahlstrom J, Dahal UP, Jiang M, Stauber J, David B, Siska W…, Monticello TM. 2021. Mercapturate pathway metabolites of sotorasib, a covalent inhibitor of KRASG12C, are associated with renal toxicity in the Sprague Dawley rat. Toxicol Appl Pharmacol 423(July 15):11578; doi: 10.1016/taap.2021.115578.

Use of acceptable daily intake (ADI) as a health-based benchmark in nutrition research studies that consider the safety of low-calorie sweeteners (LCS): A systematic map

Fitch SE, Payne LE, van de Ligt JLG, Doepker C, Handu D, Cohen SM, Anyangwe N, Wikoff D. 2021. Use of acceptable daily intake (ADI) as a health-based benchmark in nutrition research studies that consider the safety of low-calorie sweeteners (LCS): A systematic map. BMC Pub Health 21(1):956; doi: 10.1186/s12889-021-10934-2. PMID: 34016063.

A systematic approach to evaluate plausible modes of [action] for mouse lung tumors in mice exposed to 4-methylimidozole

Borghoff SJ, Fitch SE, Black MVB, McMullen PD, Andersen ME, Chappell GA. 2021. A systematic approach to evaluate plausible modes of [action] for mouse lung tumors in mice exposed to 4-methylimidozole. Regul Toxicol Pharmacol 124(Aug):104977; doi: 10.1016/j.yrtph.2021.104977. PMID: 34174380.

Racial/ethnic and sex representation in US-based clinical trials of hearing loss management in adults: A systematic review

Pittman CA, Roura R, Price C, Lin FR, Marrone N, Nieman CL. 2021. Racial/ethnic and sex representation in US-based clinical trials of hearing loss management in adults: A systematic review. JAMA Otolaryngol: Head Neck Surg 147(7):656–662; https://doi.org/10.1001/jamaoto.2021.0550.

Telemedicine and dementia care: A systematic review of barriers and facilitators

Yi JS, Pittman CA, Price CL, Nieman CL, Oh ES. 2021. Telemedicine and dementia care: A systematic review of barriers and facilitators. J Am Med Direct Assoc; 22(7):P1396-P1402; https://doi.org/10.1016/j.jamda.2021.03.015