Publications
carcinogens (54 POSTS)
2010 (1 POST)
Characterizing and predicting carcinogenicity and mode-of-action using conventional and toxicogenomics methods
Waters MD, Jackson MA, Lea IA. 2010. Characterizing and predicting carcinogenicity and mode-of-action using conventional and toxicogenomics methods. Mutat Res 705(3):184–200; doi: 10.1016/j.mrrev.2010.04.005.
View Abstract2007 (1 POST)
Mode-of-action framework for evaluating the relevance of rodent forestomach tumors in cancer risk assessment
Proctor DM, Gatto NM, Hong SJ, Allamneni KP. 2007. Mode-of-action framework for evaluating the relevance of rodent forestomach tumors in cancer risk assessment. Toxicol Sci 98(2):313–326; doi: 10.1093/toxsci/kfm075.
View Abstract2006 (1 POST)
The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is predictive of colon DNA adducts after a low-dose exposure in humans
Malfatti MA, Dingley KH, Nowell-Kadlubar S, Ubick EA, Mulakken N, Nelson D, Lang NP, et al. 2006. The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is predictive of colon DNA adducts after a low-dose exposure in humans. Cancer Res 66(21):10541–10547; doi: 10.1158/0008-5472.CAN-06-1573. PMID: 17079477.
View Abstract2004 (3 POSTS)
Characterization of a peptide adduct formed by N-acetoxy-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), a reactive intermediate of the food carcinogen PhIP
Chepanoske CL, Brown K, Turteltaub KW, Dingley KH. 2004. Characterization of a peptide adduct formed by N-acetoxy-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), a reactive intermediate of the food carcinogen PhIP. Food Chem Toxicol 42(8):1367–1372; doi: 10.1016/j.fct.2003.11.012. PMID: 15207388.
View AbstractOchratoxin A: Lack of formation of covalent DNA adducts
Mally A, Zepnik H, Wanek P, Eder E, Dingley K, Ihmels H., et al. 2004. Ochratoxin A: Lack of formation of covalent DNA adducts. Chem Res Toxicol 17(2):234–242; doi: 10.1021/tx034188m. PMID: 14967011.
View AbstractPeroxisome proliferator-activated receptor beta (delta)-dependent regulation of ubiquitin C expression contributes to attenuation of skin carcinogenesis
Kim DJ, Akiyama TE, Harman FS, Burns AM, Shan W, Ward JM, Kennett MJ, Gonzalez FJ, Peters JM. 2004. Peroxisome proliferator-activated receptor beta (delta)-dependent regulation of ubiquitin C expression contributes to attenuation of skin carcinogenesis. J Biol Chem 279(22):23719-23727; doi: 10.1074/jbc.M312063200. PMID: 15033975.
View Abstract2003 (1 POST)
The effects of coffee on enzymes involved in metabolism of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rats
Turesky RJ, Richoz J, Constable A, Curtis KD, Dingley KH, Turteltaub KW. 2003. The effects of coffee on enzymes involved in metabolism of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rats. Chem-Biol Interact 145(3):251–265; doi: 10.1016/S0009-2797(03)00022-X. PMID: 12732453.
View Abstract2002 (1 POST)
Evaluation of the carcinogenicity of 1,1-dichloroethylene (vinylidene chloride)
Roberts SM, Jordan KE, Warren DA, Britt JK, James RC. 2002. Evaluation of the carcinogenicity of 1,1-dichloroethylene (vinylidene chloride). Regul Toxicol Pharmacol 35(1):44-55; doi: 10.1006/rtph.2001.1518.
View Abstract1994 (2 POSTS)
Two approaches for assessing human cancer risk from disperse blue 1
Haws LC, Jackson BA, Turnbull D, Dressler WE. 1994. Two approaches for assessing human cancer risk from disperse blue 1. Regul Toxicol Pharmacol. 19(1):80-96; doi: 10.1006/rtph.1994.1007.
View AbstractCell proliferation and formaldehyde-induced respiratory carcinogenesis.
Monticello TM, Morgan KT. 1994. Cell proliferation and formaldehyde-induced respiratory carcinogenesis. Risk Anal 14(3):313-319; doi: 10.1111/j.1539-6924.1994.tb00246.x.
View Abstract1991 (3 POSTS)
Secondary mechanisms in carcinogenesis: Breaking out of the no-threshold paradigm
Jackson BA. Haws LC, Wixtrom RJ, Starr TB. Secondary mechanisms in carcinogenesis: Breaking out of the no-threshold paradigm. American College of Toxicology Annual Meeting, Savannah, GA, 1991.
Chemically induced cell proliferation in upper respiratory tract carcinogenesis
Monticello TM, Renne R, Morgan KT. 1991. Chemically induced cell proliferation in upper respiratory tract carcinogenesis. Prog Clin Biol Res 369:323-225.
Examination of potential mechanisms of carcinogenicity of 1,4-dioxane in rat nasal epithelial cells and hepatocytes
Goldsworthy TL, Monticello TM, Morgan KT, Bermudez E, Wilson D, Butterworth BE. 1991. Examination of potential mechanisms of carcinogenicity of 1,4-dioxane in rat nasal epithelial cells and hepatocytes. Arch Toxicol 65(1):1-9; doi: 10.1007/BF01973495.
View Abstract1989 (1 POST)
Airflow, mucociliary clearance, and lesion distribution in the nasal passages of experimental animals
Morgan KT, Monticello TM. 1989. Airflow, mucociliary clearance, and lesion distribution in the nasal passages of experimental animals. In: Feron VJ, Bosland MC (eds), Nasal Carcinogenesis in Rodents: Relevance to Human Risk. Wageningen, Netherlands: Pudec Publications, pp. 36-41.