Published Papers (1146 POSTS)

2017 (54 POSTS)

A global human health risk assessment for octamethylcyclotetrasiloxane (D4)

Gentry R, Franzen A, Van Landingham C, Greene T, Plotzke K. 2017. A global human health risk assessment for octamethylcyclotetrasiloxane (D4). Regul Toxicol Pharmacol 279(Sup 1):23-41; doi: 10.1016/j.toxlet.2017.05.019.

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Improved physiologically based pharmacokinetic model for oral exposures to chromium in mice, rats, and humans to address temporal variation and sensitive populations

Kirman CR, Suh M, Proctor DM, Hays SM. 2017. Improved physiologically based pharmacokinetic model for oral exposures to chromium in mice, rats, and humans to address temporal variation and sensitive populations. Toxicol Appl Pharmacol 325(15 June):9-17; doi: 10.1016/j.taap.2017.03.023.

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The TGx-28 65 biomarker online application for analysis of transcriptomics data to identify DNA damage-inducing chemicals in human cell cultures

Jackson MA, Yang L, Lea I, Rashid A, Kuo B, Williams A, Lyn Yauk C, Fostel J. 2017. The TGx-28 65 biomarker online application for analysis of transcriptomics data to identify DNA damage-inducing chemicals in human cell cultures. Environ Mol Mutagen 58(7):529–535; doi: 10.1002/em.22114.

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Biomarkers for nonclinical infusion reactions in marketed biotherapeutics and considerations for study design

Mease K, Kimzey A, Lansita J. 2017. Biomarkers for nonclinical infusion reactions in marketed biotherapeutics and considerations for study design. Curr Opin Toxicol 4(June):1–15; doi: 10.1016/j.cotox.2017.03.005.

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Multivariate models for prediction of human skin sensitization hazard

Strickland J, Zang Q, Paris M, Lehmann DM, Allen D, Choksi N, et al. 2017. Multivariate models for prediction of human skin sensitization hazard. J Appl Toxicol 37:347–360; doi: 10.1002/jat.3366.

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A comprehensive annotated database of toxicological data

Lea IA, Gong H, Paleja A, Rashid, A, Foster J. 2017. CEBS: A comprehensive annotated database of toxicological data. Nucleic Acids Res 45(D1):D964–D971; doi: 10.1093/nar/gkw1077.

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Derivation of an oral toxicity reference value for nickel

Haber LT, Bates HK, Allen BC, Vincent MJ, Oller AR. 2017. Derivation of an oral toxicity reference value for nickel. Regul Toxicol Pharmacol 87(S1–S18), doi: 10.1016/j.yrtph.2017.03.011.

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Cleaning and asthma: A systematic review and approach for effective safety assessment

Vincent MJ, Parker A, Maier A. 2017. Cleaning and asthma: A systematic review and approach for effective safety assessment. Regul Toxicol Pharmacol 90(Nov):231–243; doi: 10.1016/j.yrtph.2017.09.013.

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Chemical-induced asthma and the role of clinical, toxicological, exposure and epidemiological research in regulatory and hazard characterization approaches

Vincent MJ, Bernstein JA, Basketter D, LaKind JS, Dotson GS, Maier A. 2017. Chemical-induced asthma and the role of clinical, toxicological, exposure and epidemiological research in regulatory and hazard characterization approaches. Regul Toxicol Pharmacol 90(Nov):126–132; doi: 10.1016/j.yrtph.2017.08.018.

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Use and utility of animal models of disease for nonclinical safety assessment: A pharmaceutical industry survey

Morgan SJ, Couch J, Guzzie-Peck P, Keller DA, Kemper R, Otieno MA, Schulingkamp RJ, Jones TW. 2017. Regulatory forum opinion piece: Use and utility of animal models of disease for nonclinical safety assessment: A pharmaceutical industry survey. Toxicol Pathol 45(3):372–380; doi: 10.1177/0192623317701004.

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Evaluation of therapeutics for advanced-stage heart failure and other severely-debilitating or life-threatening diseases

Prescott JS, Andrews PA, Baker RW, Bogdanffy MS, Fields FO, Keller DA, Lapadula DM, Mahoney NM, Paul DE, Platz SJ, Reese DM, Stoch SA, DeGeorge JJ. 2017. Evaluation of therapeutics for advanced-stage heart failure and other severely-debilitating or life-threatening diseases. Clin Pharmacol Ther 102(2):219–227, doi: 10.1002/cpt.730.

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Navigating tissue chips from development to dissemination: A pharmaceutical industry perspective

Ewart L, Fabre K, Chakilam A, Dragan Y, Duignan DB, Eswaraka J, Gan J, Guzzie-Peck P, Otieno M, Jeong CG, Keller DA, de Morais SM, Phillips JA, Proctor W, Sura R, Van Vleet T, Watson D, Will Y, Tagle D, Berridge B. 2017. Navigating tissue chips from development to dissemination: A pharmaceutical industry perspective. Exp Biol Med (Maywood) 242(16):1579–1585, doi: 10.1177/1535370217715441.

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Current nonclinical testing paradigm enables safe entry to first-in-human clinical trials: The IQ consortium nonclinical to clinical translational database

Monticello TM, Jones TW, Dambach DM, Potter DM, Bolt MW, Liu M, Keller DA, Hart TK, Kadambi VJ. 2017. Current nonclinical testing paradigm enables safe entry to first-in-human clinical trials: The IQ consortium nonclinical to clinical translational database. Toxicol Appl Pharmacol 334:100–109, doi: 10.1016/j.taap.2017.09.006.

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Cardiometabolic risk and gut microbial phytoestrogen metabolite phenotypes

Frankenfeld CL. 2017. Cardiometabolic risk and gut microbial phytoestrogen metabolite phenotypes. Mol Nutr Food Res 61(1):1500900; doi: 10.1002/mnfr.201500900.

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Being overweight or obese is associated with harboring a gut microbial community not capable of metabolizing the soy isoflavone daidzein to O-desmethylangolensin in soy-consuming peri- and post-menopausal women

Miller LM, Lampe JW, Newton KM, Gundersen G, Fuller S, Reed SD, Frankenfeld CL. 2017. Being overweight or obese is associated with harboring a gut microbial community not capable of metabolizing the soy isoflavone daidzein to O-desmethylangolensin in soy-consuming peri- and post-menopausal women. Maturitas 99:37–42, https://doi.org/10.1016/j.maturitas.2017.02.006.

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Dietary protein intake above the current RDA and bone health: A systematic review and meta-analysis

Wallace TC, Frankenfeld CL. 2017. Dietary protein intake above the current RDA and bone health: A systematic review and meta-analysis. J Am Coll Nutr 36:481–496, https://doi.org/10.1080/07315724.2017.1322924.

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Cross-sectional analysis of the association between bedtime and malaria exposure in the Ouest and Sud-Est Departments of Haiti

Stephenson CJ, Rossheim ME, Frankenfeld CL, Boncy J, Okech BO, von Fricken ME. 2017. Cross-sectional analysis of the association between bedtime and malaria exposure in the Ouest and Sud-Est Departments of Haiti. Acta Tropica 176:188–191, https://doi.org/10.1016/j.actatropica.2017.08.011.

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Trends in employer postings for epidemiology jobs: An analysis of publichealthjobs.net data from 2003-2016

Frankenfeld CL. 2017. Trends in employer postings for epidemiology jobs: An analysis of publichealthjobs.net data from 2003-2016. Ann Epidemiol 27:553–557, https://doi.org/10.1016/j.annepidem.2017.08.007.

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Risk assessments for invasive plants: A Midwestern US comparison

Buerger AN, Howe K, Jacquart E, Chandler M, Culley T, Evans C, et al. 2015. Risk assessments for invasive plants: A Midwestern US comparison. Invas Plant Sci Manage 9(1):41–54; doi: 10.1614/IPSM-D-15-00018.1.

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Atrazine exposure elicits copy number alterations in the zebrafish genome

Wirbisky SE, Freeman JL. 2017. Atrazine exposure elicits copy number alterations in the zebrafish genome. Comp Biochem Physiol C Toxicol Pharmacol 194:1–8; doi: 10.1016/j.cbpc.2017.01.003.

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