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PBPK/PBDE (50 POSTS)

2005 (4 POSTS)

Toxicokinetics of BDE 47 in female mice: Effects of dose, route of exposure, and time

Staskal DF, Diliberto JJ, DeVito MJ, Birnbaum LS. 2005. Toxicokinetics of BDE 47 in female mice: Effects of dose, route of exposure, and time. Toxicol Sci. 83(2):215-23; doi: 10.1093/toxsci/kfi018.

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2004 (2 POSTS)

Polybrominated diphenyl ether contamination of United States food

Schecter, A, Papke O, Tung KC, Staskal DF, Birnbaum L. 2004. Polybrominated diphenyl ether contamination of United States food. Environ Sci Technol 38(20):5306-5311; doi: 10.1021/es0490830.

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Disposition of 2,2’,4,4’-tetrabromodiphenylether (BDE 47) in female mice

Staskal DF, Diliberto JJ, DeVito MJ, Birnbaum LS. Disposition of 2,2’,4,4’-tetrabromodiphenylether (BDE 47) in female mice. Society for Toxicology 43rd Annual Meeting, Baltimore, MD, March 2004.

2001 (1 POST)

Development of a physiologically based pharmacokinetic model of isopropanol and its metabolite acetone

Clewell HJ, Gentry PR, Gearhart JM, Covington TR, Banton MI, Andersen ME. 2001. Development of a physiologically based pharmacokinetic model of isopropanol and its metabolite acetone. Toxicol Sci 63(2):160–172; doi: 10.1093/toxsci/63.2.160.

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2000 (3 POSTS)

Development of a physiologically-based pharmacokinetic model of trichloroethylene and its metabolites for use in risk assessment

Clewell HJ III, Gentry PR, Allen BC, Covington TR, Gearhart JM. 2000. Development of a physiologically-based pharmacokinetic model of trichloroethylene and its metabolites for use in risk assessment. Environ Health Perspect 108(Suppl 2):283–305; doi: 10.1289/ehp.00108s2283.

View Abstract

Investigation of the impact of benchmark and PBPK modeling on the derivation of MRLs

Gentry R, Clewell H, Covington T, Wilson J. Investigation of the impact of benchmark and PBPK modeling on the derivation of MRLs. Poster presented at Society of Toxicology 39th Annual Meeting, Philadelphia, PA, March 2000.

Development of a physiologically-based pharmacokinetic (PB-PK) model and human health risk assessment for coumarin

Clewell HJ, Gentry PR, Gearhart JM, Born SL, Lehman-McKeeman LD, Covington TR. Development of a physiologically-based pharmacokinetic (PB-PK) model and human health risk assessment for coumarin. Poster presented at Society of Toxicology 39th Annual Meeting, Philadelphia, PA, March 2000.

1999 (2 POSTS)

Evaluation of the uncertainty in an oral reference dose for methylmercury due to interindividual variability in pharmacokinetics

Clewell HJ, Gearhart JM, Gentry PR, Covington TR, Van Landingham CB, Crump KS, and Shipp AM. 1999. Evaluation of the uncertainty in an oral reference dose for methylmercury due to interindividual variability in pharmacokinetics. Risk Anal 19(4):541–552; doi: 10.1111/j.1539-6924.1999.tb00427.x.

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Development of a physiologically-based pharmacokinetic (PB-PK) model for isopropanol and acetone

Gentry R, Clewell H, Gearhart J, Covington T, Andersen M. Development of a physiologically-based pharmacokinetic (PB-PK) model for isopropanol and acetone. Poster presented at  Society of Toxicology 38th Annual Meeting, New Orleans, LA, March 1999.

1996 (1 POST)

Developing physiologically-based pharmacokinetic (PB-PK) models for manganese and iron

Covington TR, Clewell HJ III, Gearhart JM, Andersen ME. Developing physiologically-based pharmacokinetic (PB-PK) models for manganese and iron. Poster presented at the Society of Toxicology Annual Meeting, Anaheim, CA, March 1996.

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