Publications
Chad Thompson (162 POSTS)
2012 (15 POSTS)
Hexavalent chromium reduction kinetics in rodent stomach contents
Proctor DM, Suh M, Aylward LL, Kirman CR, Harris MA, Thompson CM, Gürleyük H, Gerads R, Haws LC, Hays SM. 2012. Hexavalent chromium reduction kinetics in rodent stomach contents. Chemosphere 89(5):487-493; doi: 10.1016/j.chemosphere.2012.04.065.
View AbstractAssessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis
Thompson CM, Fedorov Y, Brown DD, Suh M, Proctor DM, Kuriakose L, Haws L, Harris MA. 2012. Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis. PLoS ONE 7(8):e42720; doi: 10.1371/journal.pone.0042720.
View AbstractAssessment of genotoxic potential of Cr(VI) in the mouse duodenum: An in silico comparison with mutagenic and nonmutagenic carcinogens across tissues
Thompson CM, Hixon JG, Proctor DM, Haws LC, Suh M, Urban JD, Harris MA. 2012. Assessment of genotoxic potential of Cr(VI) in the mouse duodenum: An in silico comparison with mutagenic and nonmutagenic carcinogens across tissues. Regul Toxicol Pharmacol 64(1):68-76; doi: 10.1016/j.yrtph.2012.05.019
View AbstractComparison of the effects of hexavalent chromium in the alimentary canal of F344 rats and B6C3F1 mice following exposure in drinking water: Implications for carcinogenic modes of action
Thompson CM, Proctor DM, Suh M, Haws LC, Hebert CD, Mann JF, Shertzer HG, Hixon JG,Harris MA. 2012. Comparison of the effects of hexavalent chromium in the alimentary canal of F344 rats and B6C3F1 mice following exposure in drinking water: Implications for carcinogenic modes of action. Toxicol Sci 125(1):79-90; doi: 10.1093/toxsci/kfr280.
View AbstractGenome-wide gene expression analysis of Cr(VI) effects in Fisher rat small intestinal epithelium
Kim S, Kopec A, Forgacs AL, Thompson CM, Zacharewski T. Genome-wide gene expression analysis of Cr(VI) effects in Fisher rat small intestinal epithelium. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
View AbstractDuodenal GSH/GSSG ratios in mice following oral exposure to Cr(VI)
Thompson CM, Proctor DM, Harris MA. 2012. Duodenal GSH/GSSG ratios in mice following oral exposure to Cr(VI). Toxicol Sci 126(1):287-288; doi: 10.1093/toxsci/kfr337.
View AbstractComparative toxicogenomic analysis of Cr(VI) effects in rat and mouse small intestine
Kopec A, Forgacs AL, Kim S, Thompson CM, Zacharewski T. Comparative toxicogenomic analysis of Cr(VI) effects in rat and mouse small intestine. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
View AbstractK-ras codon 12 GGT to GAT mutation is not elevated in the duodenum of mice subchronically exposed to hexavalent chromium in drinking water
O’Brien TJ, Hao D, Suh M, Proctor D, Thompson CM, Harris MA, Parsons BL, Meyers MB. 2012. K-ras codon 12 GGT to GAT mutation is not elevated in the duodenum of mice subchronically exposed to hexavalent chromium in drinking water. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.
View AbstractMode of action for intestinal carcinogenesis of ingested hexavalent chromium in mice
Proctor DM, Thompson CM, Suh M, Haws LC, Harris MA. 2012. Mode of action for intestinal carcinogenesis of ingested hexavalent chromium in mice. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
View AbstractAssessment of genotoxic potential of Cr(VI) in the mouse duodenum via toxicogenomic profiling
Thompson CM, Hixon JG, Kopec AK, Harris MA, Proctor DM, Haws LC. Assessment of genotoxic potential of Cr(VI) in the mouse duodenum via toxicogenomic profiling. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
View AbstractA genomics-based benchmark dose analyses of relative potencies of dioxin-like compounds in primary rat hepatocytes
Urban J, Rowlands JC, Budinsky R, Dombkowski A, Thompson CM, Thomas RS. A genomics-based benchmark dose analyses of relative potencies of dioxin-like compounds in primary rat hepatocytes. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
View Abstract2011 (11 POSTS)
Derivation of an oral reference dose and drinking water screening level for sulfolane using benchmark dose modeling
Thompson C, Perry C, Gaylor D, Tachovsky A, Burkhalter B, Haws L. Derivation of an oral reference dose and drinking water screening level for sulfolane using benchmark dose modeling. Presented at Society of Toxicology 50th Annual Meeting, Washington DC, March 2011.
View AbstractInvestigation of the mode of action underlying the tumorigenic response induced in B6C3F1 mice exposed orally to hexavalent chromium
Thompson CM, Proctor DM, Haws LC, Hebert CD, Grimes SD, Shertzer HG, Kopec AK, Hixon JG, Zacharewski TR, Harris MA. 2011. Investigation of the mode of action underlying the tumorigenic response induced in B6C3F1 mice exposed orally to hexavalent chromium. Toxicol Sci 123(1):58-70; doi: 10.1093/toxsci/kfr164.
View AbstractApplication of the U.S. EPA mode of action framework for purposes of guiding future research: A case study involving the oral carcinogenicity of hexavalent chromium
Thompson CM, Haws LC, Harris MA, Gatto NM, Proctor DM. 2011. Application of the U.S. EPA mode of action framework for purposes of guiding future research: A case study involving the oral carcinogenicity of hexavalent chromium. Toxicol Sci 119(1):20-40; doi: 10.1093/toxsci/kfq320.
View AbstractGenomic approaches for relative potency assessment
Thomas RS, Rowlands JC, Budinsky RA, Thompson CM, Urban JD. Dombkowski, A. 2011. Genomic approaches for relative potency assessment. Presented at Dioxin 2011, Brussels, Belgium, August 2011.
Derivation of relative potency estimates using benchmark dose modeling: A case study with TCDF
Wikoff DS, Thompson C, Walker N, DeVito M, Harris M, Birnbaum L, Haws L. Derivation of relative potency estimates using benchmark dose modeling: A case study with TCDF. Presented at Dioxin 2011, Brussels, Belgium, August 2011.
Considerations for the implausibility of leukemia induction by formaldehyde
Thompson CM, Grafström RC. 2011. Considerations for the implausibility of leukemia induction by formaldehyde. Toxicol Sci 120(1):230-232; doi: 10.1093/toxsci/kfq340.
View AbstractToxicogenomic profiling of formaldehyde-exposed normal and transformed human oral keratinocytes
Ceder R, Merne M, Nilsson J-A, Staab C, Höög J-O, Thompson CM, Grafström RC. Toxicogenomic profiling of formaldehyde-exposed normal and transformed human oral keratinocytes. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
View AbstractResearch plan to fill data gaps in the mode of action for cancer risk assessment of hexavalent chromium in drinking water
Haws L, Proctor D, Thompson C, Harris M. Research plan to fill data gaps in the mode of action for cancer risk assessment of hexavalent chromium in drinking water. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
View AbstractComparison of basal and CrVI-mediated solute carrier gene expression in rodent duodenal epithelium
Kim S, Thompson CM, Kopec AK, Harris MA, Zacharewski TR. Comparison of basal and CrVI-mediated solute carrier gene expression in rodent duodenal epithelium. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
View Abstract