Abstracts and Presentations (1104 POSTS)

2024 (63 POSTS)

A real-world impact of X-linked myotubular myopathy (XLMTM) on caregivers in Spain

Haselkorn T, Roca A, Miller B, Jensen I, Solomon F, Sanchez-de la Rosa R, Picart JM, Nascimento A. A real-world impact of X-linked myotubular myopathy (XLMTM) on caregivers in Spain. Presented at LXXVI Reunion Annual de la Sociedad Espanola de Nurologica, 19–23 November 2024.

Tools and tips for exposure assessment throughout the product development life cycle

Gauthier A, Bare J, Kramer M. Tools and tips for exposure assessment throughout the product development life cycle. Education session, PSX 2024, Annual Conference of the Product Stewardship Society, Denver, CO, October 2024.

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To be an orphan disease or not to be: An evaluation of prevalence estimates for cancers near the orphan status threshold and implications for orphan drug planning

Kelsh M, Bylsma LC, Jiang X, Movva N, Sacks NC. To be an orphan disease or not to be: An evaluation of prevalence estimates for cancers near the orphan status threshold and implications for orphan drug planning. International Society for Pharmacoepidemiology, 40th Annual Meeting, Berlin, Germany, August 2024.

Epidemiology is critical in advancing cumulative impact assessment (CIA) research: A pilot study in San Antonio, Texas

Suh M, Mittal L, Brorby G, Pastula S, Vincent M, Proctor D. Epidemiology is critical in advancing cumulative impact assessment (CIA) research: A pilot study in San Antonio, Texas. International Society of Exposure Science, Montreal, Canada, October 2024.

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Exploring biomarker-based methods to incorporate non-chemical stressor exposures into cumulative assessments for potentially vulnerable population groups

East A, Klaren W, Covington T, Rish W. Exploring biomarker-based methods to incorporate non-chemical stressor exposures into cumulative assessments for potentially vulnerable population groups. International Society of Exposure Science, Montreal, Canada, October 2024.

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Clustering chemicals for predicting behavior and hazards: Insights from the endocrine disruptor screening program (EDSP) universe of chemicals

Cook B, Nelms MD, Harris D, Bever RJ, Lynn SC, Borghoff S, et al. Clustering chemicals for predicting behavior and hazards: Insights from the endocrine disruptor screening program (EDSP) universe of chemicals. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.

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Prediction of chemical suitability for screening in a high-throughput assay platform using an in silico mass balance model

Covington TR, Borghoff SJ, Bacigalupi L, O’Neal S, Cook B, Nelms M, et al. Prediction of chemical suitability for screening in a high-throughput assay platform using an in silico mass balance model. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.

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Leveraging computational tools for enhanced human-in-the-loop systematic literature reviews

Lea IA, Borghoff SJ, Chew R, Bell S, Edwards S, Vasko J, et al. Leveraging computational tools for enhanced human-in-the-loop systematic literature reviews. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.

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Categorizing articles for environmental health systematic evidence mapping: A zero-shot machine learning approach using large language models

Holt JR, Chew RF, Bunnage E, Lea I, Borghoff SJ, Sayer R, et al. Categorizing articles for environmental health systematic evidence mapping: A zero-shot machine learning approach using large language models. American Society of Cellular and Computational Toxicology Annual Meeting, Research Triangle Park, NC, October 2024.

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The toxicity of microplastics explorer 2.0: Are we moving the needle forward on microplastics toxicity research?

Hampton LT, Kennedy SB, Barrick A, Wyler DB, Almroth BC, Coffin S, et al. The toxicity of microplastics explorer 2.0: Are we moving the needle forward on microplastics toxicity research? Abstract 7.03.T-05, Society of Environmental Toxicology and Chemistry, 45th Annual Meeting, Fort Worth, TX, October 2024.

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Rolling along: State of the science for tire related chemicals 6PPD and 6PPD-quinone

Lane R, Gill S, Miller EL, Kennedy S, Shankar P, Williams T, et al. Rolling along: State of the science for tire related chemicals 6PPD and 6PPD-quinone. Abstract 4.22.P-Mo-115, Society of Environmental Toxicology and Chemistry, 45th Annual Meeting, Fort Worth, TX, October 2024.

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Trends in quality and risk assessment applicability of microplastic ecotoxicity studies

Kennedy SB, Doyle D, Coffin S, Mair MM, Cowger W, Barrick A, et al. Trends in quality and risk assessment applicability of microplastic ecotoxicity studies. Abstract 7.03.P-Th-081, Society of Environmental Toxicology and Chemistry, 45th Annual Meeting, Fort Worth, TX, October 2024

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Mechanistic evaluation of 6PPD-quinone toxicity in fish

Feifarek D, Kennedy S, Panko J. Mechanistic evaluation of 6PPD-quinone toxicity in fish. Abstract 4.22.B.T-03, Society of Environmental Toxicology and Chemistry, 45th Annual Meeting, Fort Worth, TX, October 2024.

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Acute health-based screening level derivation for cyanotoxins (microcystin, cylindrospermopsin and anatoxins)

Reátegui-Zirena EG, Lange SS, Jenkins A, Heintz MM, Franke K, Perry CS, Thompson C, et al. Acute health-based screening level derivation for cyanotoxins (microcystin, cylindrospermopsin and anatoxins). Abstract 7.05P-Th-197, Society of Environmental Toxicology and Chemistry, 45th Annual Meeting, Fort Worth, TX, October 2024.

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The 18-effectiveness of atidarsagene autotemcel (ARSA-CEL) for the treatment of metachromatic leukodystrophy (MLD) in Spain

Pang F, Dean R, Jensen I, Bean K, Fields C, Miller B. The 18-effectiveness of atidarsagene autotemcel (ARSA-CEL) for the treatment of metachromatic leukodystrophy (MLD) in Spain, ISPOR Europe 2024, November 2024.

Quality and reliability evaluation of 6PPD-quinone surface water occurrence data and considerations for use in risk assessment

Bare J, Kennedy SB, Feifarek D, Panko J. Quality and reliability evaluation of 6PPD-quinone surface water occurrence data and considerations for use in risk assessment. Abstract 4.22.P-Mo-119, Society of Environmental Toxicology and Chemistry, 45th Annual Meeting, Fort Worth, TX, October 2024.

Analysis and comparison of nicotine pharmacokinetics of modern oral nicotine pouches

Keeton KA, Blanchette A, Benson SM, Covell LT, Madl AK. Analysis and comparison of nicotine pharmacokinetics of modern oral nicotine pouches. Poster Presentation 48 at the 77th Tobacco Science Research Conference, Atlanta, GA, September 2024.

Low-cost laser welding for rapid prototyping of microfluidic, Lab-on-a-Chip, and microphysiological models

Singh DK, Reynolds JI, Johnson BP. Low-cost laser welding for rapid prototyping of microfluidic, Lab-on-a-Chip, and microphysiological models. Mid-Michigan Symposium for Undergraduate Research Experiences, East Lansing, MI, 2024.

A cost-consequence analysis of ponatinib versus imatinib in patients with newly diagnosed Philadelphia-positive acute lymphoblastic leukemia in the United States

Hernandez L, Davies S, Li C, Reddick E, Jensen I. A cost-consequence analysis of ponatinib versus imatinib in patients with newly diagnosed Philadelphia-positive acute lymphoblastic leukemia in the United States. Abstract EE165, ISPOR 2024 (Top 5% Finalist).

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Comparative analysis of caco-2 cells and human enteroids (jejeunal or duodenal) in gel- and membrane-based barrier models of intestinal permeability

Moyer HL, Vergara L, Sakolish C, Lin HC, Hewitt P, Chiu WA, Stephan C, Rusyn I. Comparative analysis of caco-2 cells and human enteroids (jejeunal or duodenal) in gel- and membrane-based barrier models of intestinal permeability. Abstract 461, Microphysiological Systems (MPS) 3rd World Summit, Seattle, WA, June 2024.