Publications

Performance of the OptiSafe ocular irritation assay in a three-laboratory validation study

Choksi N, Daniel A, Lebrun S, Nguyen M, DeGeorge G, Willoughby JA, et al. Performance of the OptiSafe ocular irritation assay in a three-laboratory validation study. Poster presented at Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.

MicroRNA-223 supresses the canonical NF-kB pathway basal keratinocytes to dampen neutrophilic inflammation

Zhou W, Pal AS, Hsu AY, Gurol T, Zhu X, Wirbisky-Hershberger SE, Freeman JL, Kasinski AL, Deng Q. 2018. MicroRNA-223 supresses the canonical NF-kB pathway basal keratinocytes to dampen neutrophilic inflammation. Cell Reprod 13:1810–1823.

Classes of compounds with GI tract toxicity

Mihalchik AL, Rogers EN. 2018. Classes of compounds with GI tract toxicity. Chapter 13 in: Gad SC (ed), Toxicology of the Gastrointestinal Tract. CRC Press.

Nonclinical development of ANX005: A humanized anti-C1q antibody for treatment of autoimmune and neurodegenerative diseases

Lansita J,  Mease KM, Qiu H, Yednock T, Sankaranarayanan S, Kramer S. 2017. Nonclinical development of ANX005: A humanized anti-Clq antibody for treatment of autoimmune and neurodegenerative diseases. Int J Toxicol 36(6)449-462; doi: 10.1177/1091581817740873. PMID: 29202623.

Use of alternative methods to assess skin irritation of chemical mixtures

Sheppard A, Baker E, Bermudez D, Blattner J, Boyd K, O’Neal S, Rahim T, Whittle E. Use of alternative methods to assess skin irritation of chemical mixtures. World Congress for Alternatives to Animal Testing, Seattle, WA, 2017.

Development of a high-throughput multiplexed assay for determining chemical effects on macrophage function

Iwata Y, Klaren W, Grimm F, Rusyn I. A multidimensional high-throughput approach for toxicity evaluation of environmental chemicals in induced pluripotent stem cell-derived endothelial cells. Society of Toxicology 56th Annual Meeting, Baltimore, Md, 2017.

High-content assay multiplexing for vascular toxicity screening in induced pluripotent stem cell-derived endothelial cells and human umbilical vein endothelial cells

Iwata Y, Klaren WD, Lebakken CS, Grimm FA, Rusyn I. 2017. High-content assay multiplexing for vascular toxicity screening in induced pluripotent stem cell-derived endothelial cells and human umbilical vein endothelial cells. Assay Drug Dev Technol 15(6):267–279; doi; 10.1089/adt.2017.786. PMID: 28771372.

A comparative evaluation of five hazard screening tools

Panko J, Hitchcock K, Fung M, Spencer PJ, Kingsbury T, Mason AM. 2017. A comparative evaluation of five hazard screening tools. Integr Environ Assess Manag 13(1):139–154.

See also: Panko J, Hitchcock K, Fung M, Spencer PJ, Kingsbury T, Mason AM. 2017. Letter to the Editor: Authors’ response to Turner et al. Integr Environ Assess Manag 13(1):15–16.

The challenge of predicting problematic chemicals using a decision analysis tool: Triclosan as a case study

Perez AL, Gauthier AM, Ferracini T, Cowan DM, Kingsbury T, Panko J. 2017. The challenge of predicting problematic chemicals using a decision analysis tool: Triclosan as a case study. Integr Environ Assess Manag 13(1):198–207; doi: 10.1002/ieam.1778.

Characteristics of cobalt-related cardiomyopathy in metal hip implant patients: An evaluation of 15 published reports

Fung ES, Monnot A, Kovochich M, Unice KM, Tvermoes BE, Galbraith D, Finley BL, Paustenbach DJ. 2017. Characteristics of cobalt-related cardiomyopathy in metal hip implant patients: An evaluation of 15 published reports. Cardiovascul Toxicol 18(3):206–220.

Hospitalizations for respiratory syncytial virus disease among adults in the United States, 1997 to 2012

Pastula ST, Hackett J, Coalson J, Jiang X, Villafana T, Fryzek J. 2017. Hospitalizations for respiratory syncytial virus disease among adults in the United States, 1997 to 2012. Open Forum Infect Dis 4(1):ofw270.

Screening-level risk assessment of hydrogen fluoride exposure resulting from a thermal runaway event on an aircraft

Keenan JJ, Bare JL, McMenamy C, Chapman A, Miller E. 2017. Screening-level risk assessment of hydrogen fluoride exposure resulting from a thermal runaway event on an aircraft. Abstract #2829. Poster Presentation at Society of Toxicology (SOT) Annual Meeting, Baltimore, MD, March 2017.

Potential chemical exposures following thermal runaway in a lithium ion battery

Jacobs N, Bare JL, McMenamy C, Keenan JJ. 2017. Potential chemical exposures following thermal runaway in a lithium ion battery. Abstract #614. Poster Presentation at American Industrial Hygiene Conference & Exposition (AIHce), Seattle, WA, June 2017.

A critical review of the literature to conduct a toxicity assessment for oral exposure to methyl salicylate

Greene T, Rogers S, Franzen A, Gentry R. 2017. A critical review of the literature to conduct a toxicity assessment for oral exposure to methyl salicylate. Crit Rev Toxicol 47(2):98–120. DOI:10.1080/10408444.2016.1236071.

Toxicology of octamethylcyclotetrasiloxane (D4)

Franzen A, Greene T, Van Landingham C, Gentry R. 2017. Toxicology of octamethylcyclotetrasiloxane (D4). Toxicol Lett 279 Suppl 1:2–22. DOI:10.1016/j.toxlet.2017.06.007.

Using the Chemical Effects in Biological Systems (CEBS) database to answer pathology questions

Sheridan E, Martini C, Shaw M, Shockley K, Brix A, Rashid A, Lea I, Fostel J. Using the Chemical Effects in Biological Systems (CEBS) database to answer pathology questions. Poster P035. Presented at the 36th Annual Symposium of Society for Toxicologic Pathology, Montreal, Quebec, Canada, June 2017.

The TGx-28.65 biomarker — A web-based application using transcriptomics to identify DNA damage-inducing chemicals

Jackson M, Yang L, Yauk CL, Lea I, Kuo B, Williams A, Rashid A, Fostel J. The TGx-28.65 biomarker — A web-based application using transcriptomics to identify DNA damage-inducing chemicals. Abstract 1224. Presented at the 48th Annual Meeting of Environmental Mutagenesis and Genomics Society, Raleigh, NC, September 2017.

The TGx-28 65 biomarker online application for analysis of transcriptomics data to identify DNA damage-inducing chemicals in human cell cultures

Jackson MA, Yang L, Lea I, Rashid A, Kuo B, Williams A, Lyn Yauk C, Fostel J. 2017. The TGx-28 65 biomarker online application for analysis of transcriptomics data to identify DNA damage-inducing chemicals in human cell cultures. Environ Mol Mutagen 58(7):529–535; doi: 10.1002/em.22114.

Multivariate models for prediction of human skin sensitization hazard

Strickland J, Zang Q, Paris M, Lehmann DM, Allen D, Choksi N, et al. 2017. Multivariate models for prediction of human skin sensitization hazard. J Appl Toxicol 37:347–360; doi: 10.1002/jat.3366.

A comprehensive annotated database of toxicological data

Lea IA, Gong H, Paleja A, Rashid, A, Foster J. 2017. CEBS: A comprehensive annotated database of toxicological data. Nucleic Acids Res 45(D1):D964–D971; doi: 10.1093/nar/gkw1077.