Toxicology (397 POSTS)

2018 (28 POSTS)

Characterization of surgical smoke generated from electrocautery instruments: A pilot study

Benson SM, Maskrey JR, Nembhard M, Panko JM. Characterization of surgical smoke generated from electrocautery instruments: A pilot study. Poster at the 2018 American Occupational Health Conference (AOHC) 103rd Annual Meeting, New Orleans, LA, April 29 – May 2, 2018.

In vitro approaches to grouping of complex substances and UVCBs: A case study of olefin streams

Klaren WD, Grimm FA, Shen H, Rusyn I. In vitro approaches to grouping of complex substances and UVCBs: A case study of olefin streams. Society of Toxicology 57th Annual Meeting, San Antonio, TX, 2018.

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High-content assay multiplexing for muscle toxicity screening in human-induced pluripotent stem cell-derived skeletal myoblasts

Klaren WD, Rusyn I. 2018. High-content assay multiplexing for muscle toxicity screening in human-induced pluripotent stem cell-derived skeletal myoblasts. Assay Drug Dev Technol 16(6):333–342; doi: 10.1089/adt.2018.86. PMID: 30070899.

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In vivo efficacy of relebactam (MK-7655) in combination with imipenem/cilastatin in murine infection models

Powles MA, Galgoci A, Misura A, Colwell L, Dingley K, Tang W, et al. 2018. In vivo efficacy of relebactam (MK-7655) in combination with imipenem/cilastatin in murine infection models. Antimicrob Agents Chemother 62:e02577–17; doi: 10.1128/AAC.02577-17. PMID: 29866878.

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Optimization of preclinical metabolism for somatostatin receptor subtype 5-selective antagonists

Liu W, Hussain Z, Zang Y, Sweis RF, Romero FA, Finke PE, … Dingley KH, et al. 2018. Optimization of preclinical metabolism for somatostatin receptor subtype 5-selective antagonists. ACS Med Chem Lett (9):1088–1093; doi: 10.1021/acsmedchemlett.8b00306. PMID: 30429950.

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Methods for sterilizing clinically relevant wear particles isolated from metal-on-metal hip implants

Fung ES, Unice KM, Paustenbach DJ, Finley BL, Kovochich M. 2018. Methods for sterilizing clinically relevant wear particles isolated from metal-on-metal hip implants. Sci Rep 8(1):2384.

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Cyp2b-null male mice are susceptible to high-fat diet-induced obesity due to changes in PUFA metabolism and response to hepatic lipids as measured by RNAseq

Heintz MM, Kumar R, Baldwin WS. Cyp2b-null male mice are susceptible to high-fat diet-induced obesity due to changes in PUFA metabolism and response to hepatic lipids as measured by RNAseq. American College of Toxicology, 39th Annual Meeting, West Palm Beach, FL, November 2018.

Several toxicants increase retention of triglycerides in Daphnia magna and human liver cells

Williams TL, Heintz MM, Baldwin WS. Several toxicants increase retention of triglycerides in Daphnia magna and human liver cells. Annual Biomedical Research Conference for Minority Students (ABRCMS), Indianapolis, IN, November 2018.

Several toxicants increase retention of triglycerides in Daphnia magna and human liver cells

Williams TL, Heintz MM, Baldwin WS. Several toxicants increase retention of triglycerides in Daphnia magna and human liver cells.  Research Experiences for Undergraduates (REUs), Alexandria, VA, October 2018.

Several toxicants increase retention of triglycerides in Daphnia magna and human liver cells

Williams TL, Heintz MM, Baldwin WS. Several toxicants increase retention of triglycerides in Daphnia magna and human liver cells. Clemson Summer Research Symposium, July 2018.

The role of Cyp2b in the metabolism of unsaturated fatty acids

Heintz MM, Kumar R, Baldwin WS. The role of Cyp2b in the metabolism of unsaturated fatty acids. Abstract #1291, Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.

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Inhibition of CYP2B6 does not necessarily alter toxicity except in the case of chemicals with known active metabolites

McRee R, Heintz MM, Baldwin WS. Inhibition of CYP2B6 does not necessarily alter toxicity except in the case of chemicals with known active metabolites. Abstract #1292. Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.

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Proposition 65 risk assessment model framework for chemically-complex consumer products

Bare JL, Abramson MM, Maskrey JR, Manning CM, Keenan JJ. 2018. Proposition 65 risk assessment model framework for chemically-complex consumer products. Abstract #3525. Poster Presentation at Society of Toxicology (SOT) Annual Meeting, San Antonio, TX, March 2018.

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Potential exposure to hydrogen fluoride from a thermal runaway event in an airplane cockpit

McMenamy C, Jacobs N, Bare JL, Keenan JJ. 2018. Potential exposure to hydrogen fluoride from a thermal runaway event in an airplane cockpit. Abstract #653. Poster Presentation at American Industrial Hygiene Conference & Exposition (AIHce), Philadelphia, PA, May 2018.

And you want this by when? Making the successful transition from the bench to consulting

Mihalchik-Burhans A. And you want this by when? Making the successful transition from the bench to consulting. Oral presentation at the American College of Toxicology 39th Annual Meeting, West Palm Beach, FL, November 2018.

Improved searching in the Chemical Effects in Biological Systems (CEBS) database leads to greater utility of NTP data

Sheridan ER, Jackson M, Paleja A, Martini C, Rashid A, Lea I, Fostel J. Improved searching in the Chemical Effects in Biological Systems (CEBS) database leads to greater utility of NTP data. Abstract 2525-P887, Society of Toxicology 57th Annual Meeting, San Antonio, TX, March 2018.

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Electrolytes, blood gases and acid-base balance

Lea IA, Borghoff S, Travlos GS. 2018. Electrolytes, blood gases and acid-base balance. In: Kurtz DM, Travlos GS (eds): The Clinical Chemistry of Laboratory Animals (3rd edition). CRC Press, Boca Raton, FL (https://doi.org/10.1201/9781315155807).

The impact of genetics on the pharmacokinetics of chemicals in a U.S. Air Force population

Pangburn HA, Jarvis JP, Covington TR, Ott DK, Gearhart JM. The impact of genetics on the pharmacokinetics of chemicals in a U.S. Air Force population. Poster presented at the Society of Toxicology Annual Meeting, San Antonio, TX, March 2018.

Physiological simulation of thermal and chemical stressors in a United States Air Force population

Gearhart JM, Pitts E, Covington TR, Grabinski CM, Yamamoto DP, McKenzie-Smith D, Ott DK, Pangburn HA. Physiological simulation of thermal and chemical stressors in a United States Air Force population. Presentation at the Society of Toxicology Annual Meeting, San Antonio, TX, March 2018.

Derivation of a no-significant-risk-level for tetrabromobisphenol A based on a threshold non-mutagenic cancer mode of action

Pecquet AM, Martinez JM, Vincent M, Erraguntla N, Dourson M. 2018. Derivation of a no-significant-risk-level for tetrabromobisphenol A based on a threshold non-mutagenic cancer mode of action. J Appl Toxicol 38(6):862–878, doi: 10.1002/jat.3594.

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