Toxicology (397 POSTS)

2019 (28 POSTS)

NTP high-level summary data collections in the Chemical Effects in Biological Systems (CEBS) database

Sheridan E, Moose J, Liu Y, Martini C, Lea I, Fostel J. NTP high-level summary data collections in the Chemical Effects in Biological Systems (CEBS) database. Poster PS01-0606. Presented at 15th International Congress of Toxicology, Honolulu, HI, July 2019.

Access to National Toxicology Program histopathology lesion collection in Chemical Effects in Biological Systems (CEBS) database

Bhawana B, Lea I, Liu Y, Martini C, Fostel J. Access to National Toxicology Program histopathology lesion collection in Chemical Effects in Biological Systems (CEBS) database. Poster P040. Presented at the 38th Annual Symposium of Society for Toxicologic Pathology, Raleigh, NC, June 2019.

Hallmark gene set annotation for NTP toxicogenomic studies

Lea I, Liu Y, Sheridan E, Motti D, Martini C, Fostel J, Auerbach S. Hallmark gene set annotation for NTP toxicogenomic studies. Abstract #1743-P119. Presented at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.

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2’-Fucosyllactose is well tolerated in a 100% whey, partially hydrolyzed infant formula with Bifidobacterium lactis: A randomized controlled trial

Storm HM, Shepard J, Czerkies LM, Kineman B, Cohen SS, Reichert H, Carvalho R. 2019. 2’-Fucosyllactose is well tolerated in a 100% whey, partially hydrolyzed infant formula with Bifidobacterium lactis: A randomized controlled trial. Global Pediat Health 6:1–10; doi: 10.1177/2333794X19833995.

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Comparison of NTP OHAT and US EPA TSCA study quality criteria: Trichloroethylene (TCE) and congenital heart defects (CHDs) as a case study

Urban J, Wikoff D, Suh M, Britt J, Harvey S, Chappell G, Haws L. Comparison of NTP OHAT and US EPA TSCA study quality criteria: Trichloroethylene (TCE) and congenital heart defects (CHDs) as a case study. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

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Safety evaluation of L-theanine administered via hard chew to dogs

Henderson RG, Doepker C, Lopez JG. Safety evaluation of L-theanine administered via hard chew to dogs. Poster at Society of Toxicology 58th Annual Meeting, Baltimore, MD, March 2019.

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Novel array approach to mixtures model streamlines predictions of cochlea and brain region tissue concentrations from JP-8 inhalation exposure

Sterner TR, Covington TR, Merrill EA, Mattie DR. Novel array approach to mixtures model streamlines predictions of cochlea and brain region tissue concentrations from JP-8 inhalation exposure. Poster presented at the Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Thermal stress effects on physiologically based pharmacokinetic model for Department of Defense personnel

Pitts E, Gearhart JM, Covington TR, Duran CM, Yamamoto DP, McKenzie-Smith D, Ott DK, Pangburn HA. Thermal stress effects on physiologically based pharmacokinetic model for Department of Defense personnel. Poster presented at the Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Translating an existing physiologically-based pharmacokinetic model for isopropanol from a scalar to an array format

Covington TR. Translating an existing physiologically-based pharmacokinetic model for isopropanol from a scalar to an array format. Poster presented at the Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

Meta-regression analysis of the effects of dietary cholesterol intake on LDL and HDL cholesterol

Vincent MJ, Allen BA, Palacios OM, Haber LT, Maki KC. 2019. Meta-regression analysis of the effects of dietary cholesterol intake on LDL and HDL cholesterol. Am J Clin Nutr 109(1):7–16, doi: 10.1093/ajcn/nqy273.

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Prevalidation of the OptiSafe ocular irritation assay for the detection of ocular corrosives

Lebrun SJ, Choksi N, Daniel A, Allen D, Casey W. Prevalidation of the OptiSafe ocular irritation assay for the detection of ocular corrosives. Poster presented at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

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Using alternatives assessment approaches to inform the ranking of TRI-listed solvent chemicals

Brown L, Forth H, Reichle L, Casner AJ, McFadden A. Using alternatives assessment approaches to inform the ranking of TRI-listed solvent chemicals. Poster presented at Society for Risk Analysis, Arlington, VA, 2019.

Vascular expression of hemoglobin alpha in Antarctic icefish supports iron limitation as novel evolutionary driver

Corliss BA, Delalio LJ, Stevenson Keller TC 4th, Keller AS, Keller DA, Corliss BH, Beers JM, Peirce SM, Isakson BE. 2019. Vascular expression of hemoglobin alpha in Antarctic icefish supports iron limitation as novel evolutionary driver. Front Physiol 10:1389, doi: 10.3389/fphys.2019.01389.

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Considerations for leachables and extractables testing

Mihalchik-Burhans AL, Rogers EN. 2019. Considerations for leachables and extractables testing. In: Gad S (ed), Integrated Safety and Risk Assessment for Medical Devices and Combination Products, pp. 239–263. Springer.

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Bridging issues of route

Mihalchik-Burhans AL, Sullivan DW. 2019. Bridging issues of route. In: Gad S (ed), Integrated Safety and Risk Assessment for Medical Devices and Combination Products, pp. 273–297. Springer.

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2018 (28 POSTS)

Immunophenotyping in drug development

Kimzey AL, Piche M-S, Wood M, Weir AB, Lansita J. 2018. 11.19 – Immunophenotyping in drug development. In: Comprehensive Toxicology, 3rd Ed. Vol 11:399–427.

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Toxicological effects of tire wear particles on mummichogs and fathead minnows

LaPlaca SB. Toxicological effects of tire wear particles on mummichogs and fathead minnows. Poster presentation at annual meeting of the Society of Environmental Toxicology and Chemistry, North America Chapter, Sacramento, CA, November 2018.

issue-based mapping of the fathead minnow (Pimephales promelas) transcriptome and proteome

Lavelle C, Smith LC, Bisesi JH, Yu F, Silva-Sanchez C, Moraga-Amador D, Buerger AN, et al. 2018. Tissue-based mapping of the fathead minnow (Pimephales promelas) transcriptome and proteome. Front Endocrinol 9:611.

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NTP Research Report on baseline characteristics of Diversity Outbred (J:DO) mice relevant to toxicology studies

Harrill AH, Borghoff S, Zorrilla L, Blystone C, Kissling GE, Malarkey D, Shockley K, Travlos G, DeVito MJ. 2018. NTP Research Report on baseline characteristics of Diversity Outbred (J:DO) mice relevant to toxicology studies. National Toxicology Program Research Report 6, Research Triangle Park, NC.

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A physiologically-based pharmacokinetic model to address physiological changes associated with high-performance aircraft flight

Covington TR, Ott DK, Gearhart JM, Pangburn HA. A physiologically-based pharmacokinetic model to address physiological changes associated with high-performance aircraft flight. Presentation at the Annual Meeting of the Military Health System Research Symposium, Orlando, FL, August 2018.