Publications
Toxicology (397 POSTS)
2020 (27 POSTS)
Classifying polycyclic aromatic hydrocarbons by carcinogenic potency using in vitro biosignatures
Chang Y, Huynh CTT, Bastin KM, Rivera BN, Siddens LK, Tilton SC. 2020. Classifying polycyclic aromatic hydrocarbons by carcinogenic potency using in vitro biosignatures. Toxicol in Vitro 69:104991, doi: 10.1016/j.tiv.2020.104991.
View AbstractA comprehensive comparison of indoor vs outdoor air quality across the United States
Rivera BN, Ghetu C, Rohlman D, Adams K, Anderson K. A comprehensive comparison of indoor vs outdoor air quality across the United States. Society of Environmental Toxicology and Chemistry, virtual meeting, November 2020.
Advancing toward normal operations for arenas and stadiums.
Parker J, Boles C, Leleck O, Buerger AN, Egnot N, Sunderman A, et al. 2020. Advancing toward normal operations for arenas and stadiums. Toxicol Ind Health 36(9):718–727.
View AbstractThe process and challenges of deriving exposure-based limits for toxicological risk assessment for components and impurities present in cell therapy products with case studies
Chesney A, Welsh B, Kimzey A, Lansita J. The process and challenges of deriving exposure-based limits for toxicological risk assessment for components and impurities present in cell therapy products with case studies. Poster for Society of Toxicology, Virtual Annual Meeting, 2020.
View AbstractGeneration of machine-learning models to anticipate endocrine disruption
Zorn KM, Foil DH, Russo DP, Clark AM, Hillwalker W, Feifarek D, Jones F, Klaren W, Brinkman A, Ekins S. Generation of machine-learning models to anticipate endocrine disruption. Society of Toxicology 59th Annual Meeting, virtual, 2020.
View AbstractUse of a weighted scheme for the interpretation and contextualization of in vitro and in silico-derived estrogenic endpoints
Brinkman AM, Klaren WD, Feifarek DJ, Hillwalker W, Jones F, Zorn KM, Ekins S. Use of a weighted scheme for the interpretation and contextualization of in vitro and in silico-derived estrogenic endpoints. Society of Toxicology 59th Annual Meeting, virtual, 2020.
View AbstractMachine learning models for estrogen receptor bioactivity and endocrine disruption prediction
Zorn KM, Foil DH, Lane TR, Russo DP, Hillwalker W, Feifarek DJ, Jones F, Klaren WD, Brinkman AM, Ekins S. 2020. Machine learning models for estrogen receptor bioactivity and endocrine disruption prediction. Environ Sci Technol 54(19):12202–12213; doi: 10.1021/acs.est.0c03982. PMID: 32857505.
View AbstractGrouping of UVCB substances with new approach methodologies (NAMs) data
House JS, Grimm FA, Klaren WD, Dalzell A, Kuchi S, Zhang S, Lenz K, Boogaard PJ, Ketelsegers HB, Gant TW, Wright FA, Rusyn I. 2020. Grouping of UVCB substances with new approach methodologies (NAMs) data. ALTEX 38(1):123–137; doi: 10.14573/altex.2006262.
View AbstractComparing machine learning models for aromatase (P450 19A1)
Zorn KM, Foil DH, Lane TR, Hillwalker W, Feifarek DJ, Jones F, Klaren WD, Brinkman AM, Ekins S. 2020. Comparing machine learning models for aromatase (P450 19A1). Environ Sci Technol 54(23):15546–15555; doi: 10.1021/acs.est.0c05771. PMID: 33207874.
View AbstractGender differences in diet-induced steatotic disease in Cyp2b-null mice
Heintz MM, McRee, R, Kumar, R, Baldwin, WS. 2020. Gender differences in diet-induced steatotic disease in Cyp2b-null mice. PLoS ONE 15(3):e0229896; doi: 10.1371/journal.pone.0229896.
View AbstractDeveloping a defined approach for eye irritation testing
Choksi N, Clippinger AJ, Gehen S, Corvaro M, Kolle SN, Bentley K, et al. Developing a defined approach for eye irritation testing. Poster presented at Society of Toxicology 59th Annual Meeting, Virtual, March 2020.
View AbstractToxicological effects of micronized tire crumb rubber on mummichog (Fundulus heteroclitus) and fathead minnow (Pimephales promelas)
LaPlaca SB, van den Hurk P. 2020. Toxicological effects of micronized tire crumb rubber on mummichog (Fundulus heteroclitus) and fathead minnow (Pimephales promelas). Ecotoxicology 29(5):524–534, doi:10.1007/s10646-020-02210-7
View AbstractSensitivity and Monte Carlo analysis techniques and their use in uncertainty, variability, and population analysis
Covington TR, Gearhart JM. 2020. Sensitivity and Monte Carlo analysis techniques and their use in uncertainty, variability, and population analysis. In: Fisher JW, Gearhart JM, Lin Z (eds), Physiologically Based Pharmacokinetic (PBPK) Modeling, pp. 211–242. Academic Press.
NCEATM computational tools and resources supporting alternative test method development and evaluation
Bell S, Mansouri K, Phillips J, Chang X, Abedini J, Karmaus AL, Lea I, Rai R, Allen DG, Casey W, Kleinstreuer NC. NCEATM computational tools and resources supporting alternative test method development and evaluation. Abstract #2976-P607, Society of Toxicology 59th Annual Meeting, Anaheim CA, March 2020.
View AbstractValidation of the OptiSafe™ eye irritation test
Choksi N, Lebrun S, Nguyen M, Daniel A, DeGeorge G, Willoughby J, et al. 2020. Validation of the OptiSafe Eye Irritation Test. Cutan Ocul Toxicol 39(3):180–192; doi: 10.1080/15569527.2020.1787431.
View AbstractTime-integrated exposures to identify chemical profiles between health and dysphagic foals
Rivera BN, Mullen K, Tidwell L, Ivanek R, Ainsworth D, Tilton S, Anderson K. Time-integrated exposures to identify chemical profiles between health and dysphagic foals. New Frontiers in Dynamic Toxicology, Society of Toxicology Virtual Annual Meeting, March 2020.
Derivation of cancer no significant risk levels and screening safety assessment for 2-nitropropane in spray products
Gadagbui B, Moore J, Parker A, McCready D, Monnot AD, Garnick L, Vincent M, et al. 2020. Derivation of cancer no significant risk levels and screening safety assessment for 2-nitropropane in spray products. J Appl Tox 40(5):691–705, doi: 10.1002/jat.3937.
View AbstractHuman CYP2B6 is an anti-obesity enzyme that produces active α-linolenic acid metabolites
Heintz MM, Olack EM, Baldwin WS. Human CYP2B6 is an anti-obesity enzyme that produces active α-linolenic acid metabolites. Society of Toxicology 59th Annual Meeting, Virtual, March 2020.
View AbstractGender differences in diet-induced nonalcoholic steatohepatitis (NASH) in Cyp2b-null mice
Heintz MM, McRee R, Kumar R, Baldwin WS. Gender differences in diet-induced nonalcoholic steatohepatitis (NASH) in Cyp2b-null mice. Society of Toxicology 59th Annual Meeting, Virtual, March 2020.
View AbstractComparison and analysis of discrepancies among commonly used Cramer decision tree methods in Toxtree software
Rogers EN, Mihalchik AL, Gad, SC. Comparison and analysis of discrepancies among commonly used Cramer decision tree methods in Toxtree software. Abstract no. 1517. Society of Toxicology 59th Annual Meeting, Virtual, 2020.
View Abstract