Toxicology (397 POSTS)

2003 (11 POSTS)

Zinc influences the in vitro development of peri-implantation mouse embryos

Hanna LA, Clegg MS, Momma T, Rogers JM, Daston GP, Keen CL. 2003. Zinc influences the in vitro development of peri-implantation mouse embryos. Birth Defects Res A 67(6):414–420; doi: 10.1002/bdra.10046.

View Abstract

The embryolethality of lipopolysaccharide in CD-1 and metallothionein I-II null mice: Lack of a role for induced zinc deficiency or metallothionein induction

Leazer TM, Daston GP, Keen CL, Rogers JM. 2003. The embryolethality of lipopolysaccharide in CD-1 and metallothionein I-II null mice: Lack of a role for induced zinc deficiency or metallothionein induction. Toxicol Sci 73(2):442–447; doi: 10.1093/toxsci/kfg088.

View Abstract

Gestational exposure to ethane dimethanesulfonate permanently alters reproductive competence in the CD-1 mouse

Tarka-Leeds DK, Suarez JD, Roberts NL, Rogers JM, Hardy MP, Klinefelter GR. 2003. Gestational exposure to ethane dimethanesulfonate permanently alters reproductive competence in the CD-1 mouse. Biol Reprod 69(3):959–967; doi: 10.1095/biolreprod.103.017343.

View Abstract

Screening for developmental toxicity of tobacco smoke constituents

Rogers JM, Abbott BD. 2003. Screening for developmental toxicity of tobacco smoke constituents. Toxicol Sci 75(2):227–228; doi: 10.1093/toxsci/kfg215.

View Abstract

Chemically-induced supernumerary ribs in CD-1 mice: Size distribution and dose-response

Rogers JM, Setzer RW, Branch S, Chernoff N. 2003. Chemically-induced supernumerary ribs in CD-1 mice: Size distribution and dose-response. Birth Defects Res B 71(1):17–25; doi: 10.1002/bdrb.10055.

View Abstract

Evaluation of the potential impact of age- and gender-specific lung morphology and ventilation rate on the dosimetry of vapors

Sarangapani R, Gentry PR, Covington TR, Teeguarden JG, and Clewell HJ. 2003. Evaluation of the potential impact of age- and gender-specific lung morphology and ventilation rate on the dosimetry of vapors. Inhal Toxicol 15(10):987–1016.

View Abstract

Application of a physiologically based pharmacokinetic model for reference dose and reference concentration estimation for acetone

Gentry PR, Covington TR, Clewell HJ, Andersen ME. 2003. Application of a physiologically based pharmacokinetic model for reference dose and reference concentration estimation for acetone. J Toxicol Environ Health A 66(23):2209–2225.

View Abstract

Role of thyroid hormones in human and laboratory animal reproductive health

Choksi NY, Jahnke GD, St Hilaire C, Shelby MD. 2003. Role of thyroid hormones in human and laboratory animal reproductive health. Birth Defects Res B Develop Reprod Toxicol 68(6):479–491; doi: 10.1210/er.2015-1106.

View Abstract

A risk assessment for inhaled arsenic based on urinary arsenic concentration using a pharmacokinetic model

Clewell H, Crump K, Covington T, Gentry R, Yeager J. A risk assessment for inhaled arsenic based on urinary arsenic concentration using a pharmacokinetic model. Poster presented at the Society of Toxicology Annual Meeting, Salt Lake City, UT, March 2003.

2002 (5 POSTS)

Review and evaluation of the potential impact of age and gender-specific pharmacokinetic differences on tissue dosimetry

Clewell HJ, Teeguarden J, McDonald T, Sarangapani R, Lawrence G, Covington T, Gentry R, Shipp A. 2002. Review and evaluation of the potential impact of age and gender-specific pharmacokinetic differences on tissue dosimetry. Crit Rev Toxicol 32(5):329–389.

View Abstract

Application of a physiologically based pharmacokinetic model for isopropanol in the derivation of a reference dose and reference concentration

Gentry PR, Covington TR, Andersen ME, Clewell HJ. 2002. Application of a physiologically based pharmacokinetic model for isopropanol in the derivation of a reference dose and reference concentration. Regul Toxicol Pharmacol 36:51–68.

View Abstract

Cytochromes P450 in brain: Function and significance

Strobel HW, Thompson CM, Antonovic L. 2001. Cytochromes P450 in brain: Function and significance. Curr Drug Metabol 2(2):199–214; doi: 10.2174/1389200013338577.

View Abstract

A novel phenylaminotetralin radioligand reveals a subpopulation of histamine H(1) receptors

Booth RG, Moniri NH, Bakker RA, Choksi NY, Nix WB, Timmerman H, Leurs R. 2002. A novel phenylaminotetralin radioligand reveals a sub-population of histamine H1 receptors. J Pharmacol Exper Therapeut 302(1):328–336; doi: 10.1124/jpet.302.1.328.

View Abstract

Analysis of recombinant mouse zona pellucida protein 2 (ZP2) constructs for immunocontraception

Lea IA, Widgren EE, O’Rand MG. 2002. Analysis of recombinant mouse zona pellucida protein 2 (ZP2) constructs for immunocontraception. Vaccine 20(11–12):1515–1523; doi: 10.1016/S0264-410X(01)00514-X.

View Abstract

2001 (4 POSTS)

Toxicological highlight. Redox redux: A closer look at conceptual low molecular weight thiols

Rogers JM, Hunter ES III. 2001. Toxicological highlight-Redox redux: A closer look at conceptual low molecular weight thiols. Toxicol Sci 62(1):1–3; doi: 10.1093/toxsci/62.1.1.

View Abstract

14C-methanol incorporation into DNA and specific proteins of organogenesis-stage mouse embryos in vitro

Huang Y-S, Held G, Andrews JE, Rogers JM. 2001. 14C-methanol incorporation into DNA and specific proteins of organogenesis-stage mouse embryos in vitro. Reprod Toxicol 15:429–435; doi: 10.1016/s0890-6238(01)00144-7.

View Abstract

Role of the acute phase response and tissue necrosis factor alpha in the developmental toxicity of lipopolysaccharide in the CD-1 mouse

Leazer TM, Rogers JM. 2001. Role of the acute phase response and tissue necrosis factor alpha in the developmental toxicity of lipopolysaccharide in the CD-1 mouse. Reprod Toxicol 16(2):173–179; doi: 10.1016/S0890-6238(02)00011-4.

View Abstract

Zonadhesin: Characterization, localization, and zona pellucida binding

Lea IA, Sivashanmugam P, O’Rand MG. 2001. Zonadhesin: Characterization, localization, and zona pellucida binding. Biol Reprod 65(6):1691–700; doi: 10.1095/biolreprod65.6.1691.

View Abstract

2000 (2 POSTS)

Application of a hybrid CFD-PBPK nasal dosimetry model in an inhalation risk assessment: An example with acrylic acid

Andersen ME, Sarangapani R, Gentry PR, Clewell HJ, Covington TR, Frederick CB. 2000. Application of a hybrid CFD-PBPK nasal dosimetry model in an inhalation risk assessment: An example with acrylic acid. Toxicol Sci 57:312–325.

View Abstract

Zinc-deficient rat embryos have increased caspase 3-like activity and apoptosis

Jankowski-Hennig MA, Clegg MS, Daston GP, Rogers JM, Keen CL. 2000. Zinc-deficient rat embryos have increased caspase 3-like activity and apoptosis. Biochem Biophys Res Commun 271(1):250–256; doi: 10.1006/bbrc.2000.2608.

View Abstract