Publications
Toxicology (397 POSTS)
2007 (16 POSTS)
Pharmacological characterization of the N27-D2L cell line: Assessment as a viable cell model for investigating D2L receptor dopaminergic-coupled functions
Urban JD, Thornley K, Wightman RW, Mailman RB. Pharmacological characterization of the N27-D2L cell line: Assessment as a viable cell model for investigating D2L receptor dopaminergic-coupled functions. Society of Toxicology 46th Annual Meeting, Charlotte, NC, March 2007.
2006 (12 POSTS)
The role of mutagenicity in describing formaldehyde-induced carcinogenicity: Possible inferences using the CIIT model
Subramaniam RP, Crump KS, Chen C, White P, Van Landingham C, Fox JF, Schlosser P, Covington TR, et al. The role of mutagenicity in describing formaldehyde-induced carcinogenicity: Possible inferences using the CIIT model. Presentation at the Annual Society for Risk Analysis Conference, Baltimore, MD, December 2006.
Consideration of uncertainties in the CIIT model for formaldehyde carcinogenicity in the human respiratory tract
Crump KS, Subramaniam R, White P, Chen C, Schlosser P, Van Landingham C, Covington TR, DeVoney D. Consideration of uncertainties in the CIIT model for formaldehyde carcinogenicity in the human respiratory tract. Presentation at the Annual Society for Risk Analysis Conference, Baltimore, MD, December 2006.
Pharmacokinetic modeling of manganese. II. Hepatic processing after ingestion and inhalation
Teeguarden JG, Dorman DC, Nong A, Covington TR, Clewell HJ III, Andersen ME. 2007. Pharmacokinetic modeling of manganese. II. Hepatic processing after ingestion and inhalation. J Toxicol Environ Health A 70:1505–1514.
View AbstractPharmacokinetic modeling of manganese. I. Dose dependencies of uptake and elimination
Teeguarden JG, Dorman DC, Covington TR, Clewell HJ III, Andersen ME. 2007. Pharmacokinetic modeling of manganese. I. Dose dependencies of uptake and elimination. J Toxicol Environ Health A 70:1493–1504.
View AbstractCasting a broad network: Fishing for mechanisms of retinoid teratogenicity
Rogers JM. 2006. Casting a broad network: Fishing for mechanisms of retinoid teratogenicity. Toxicological highlight. Toxicol Sci 94(1):1–2; doi: 10.1093/toxsci/kfl104.
View AbstractICCVAM-NICEATM-ECVAM symposium on mechanisms of chemically-induced ocular injury and recovery: Current understanding and knowledge gaps
Hamernik K, Eskes C, Merrill J, Choksi N, Allen D, Truax J, et al. 2006. ICCVAM-NICEATM-ECVAM symposium on mechanisms of chemically-induced ocular injury and recovery: Current understanding and knowledge gaps. ALTEX 23 Suppl:322–324.
View AbstractIssues in using Markov Chain Monte Carlo analysis to calibrate a PBPK model for use in risk assessment: Case studies with dichloromethane and perchloroethylene
Covington TR, Gentry P, Van Landingham CB, Clewell HJ. Issues in using Markov Chain Monte Carlo analysis to calibrate a PBPK model for use in risk assessment: Case studies with dichloromethane and perchloroethylene. Poster presented at the Society of Toxicology Annual Meeting, San Diego, CA, March 2006.
Evaluation of the relationship between in vivo rabbit eye test scores and their reversibility
Tice RR, Allen DG, Choksi NY, Truax JF, Stokes WS. Evaluation of the relationship between in vivo rabbit eye test scores and their reversibility. Poster presented at Society of Toxicology 45th Annual Meeting, San Diego, CA, March 2006.
View AbstractComparative performance of four in vitro test methods for the classification of ocular corrosives and severe irritants
Stokes WS, Choksi NY, Allen DG, Truax JF, Tice RR. Comparative performance of four in vitro test methods for the classification of ocular corrosives and severe irritants. Poster presented at Society of Toxicology 45th Annual Meeting, San Diego, CA, March 2006.
View AbstractEstimated likelihood for under- and over-classification for a sequential Draize rabbit eye test
Choksi NY, Haseman J, Allen DG, Tice RR, Stokes WS. Estimated likelihood for under- and over-classification for a sequential Draize rabbit eye test. Poster presented at Society of Toxicology 45th Annual Meeting, San Diego, CA, March 2006.
View AbstractReference substances for the validation of in vitro ocular toxicity test methods for the evaluation of ocular corrosives and severe irritants
Allen D, Blackard B, Choksi N, Truax J, Tice R, Stokes W. Reference substances for the validation of in vitro ocular toxicity test methods for the evaluation of ocular corrosives and severe irritants. Poster presented at Society of Toxicology 45th Annual Meeting, San Diego, CA, March 2006
View AbstractN27 dopaminergic cell line: A useful model for studying the mechanisms of action of functionally selective dopaminergic compounds
Urban JD, Jin J, Mailman RB. 2006. N27 dopaminergic cell line: A useful model for studying the mechanisms of action of functionally selective dopaminergic compounds. Society for Toxicology 45th Annual Meeting, San Diego, CA, March 2006.
2005 (18 POSTS)
Keratinocyte growth factor therapy in murine oleic acid-induced acute lung injury
Ulrich K, Stern M, Goddard ME, Williams J, Zhu J, Dewar A, Painter HA, Jeffery PK, Gill DR, Hyde SC, Geddes DM, Takata M, Alton Show EWFW. 2005. Keratinocyte growth factor therapy in murine oleic acid-induced acute lung injury. Lung Cell Molec Physiol 288(6):L1179-92.
View AbstractEstimated under- and over-classification rates for a 1-3 rabbit sequential Draize rabbit eye test
Haseman J, Tice RR, Allen DG, Choksi NY, Stokes WS. Estimated under- and over-classification rates for a 1-3 rabbit sequential Draize rabbit eye test. Poster presented at the 5th World Congress on Alternatives and Animal Use in the Life Sciences, Berlin, Germany, August 2005.
Proposed reference substances for optimization and validation studies with in vitro ocular test methods
Allen DG, Blackard BC, Choksi NY, Truax JF, Tice RR, Stokes WS, et al. Proposed reference substances for optimization and validation studies with in vitro ocular test methods. Poster presented at the 5th World Congress on Alternatives and Animal Use in the Life Sciences, Berlin, Germany, August 2005.
Performance of the Isolated Chicken Eye (ICE) test method in detecting ocular corrosives and severe irritants
Allen DG, Blackard BC, Choksi NY, Inhof CJ, Truax JF, Tice RR, Stokes WS. Performance of the Isolated Chicken Eye (ICE) test method in detecting ocular corrosives and severe irritants. Poster presented at the 5th World Congress on Alternatives and Animal Use in the Life Sciences, Berlin, Germany, August 2005.
Performance of the Isolated Rabbit Eye (IRE) test method in detecting ocular corrosives and severe irritants
Truax JF, Allen DG, Blackard BC, Choksi NY, Inhof CJ, Tice R, Stokes WS. Performance of the Isolated Rabbit Eye (IRE) test method in detecting ocular corrosives and severe irritants. Poster presented at the 5th World Congress on Alternatives and Animal Use in the Life Sciences, Berlin, Germany, August 2005.
Performance of the Bovine Corneal Opacity and Permeability (BCOP) test method in detecting ocular corrosives and severe irritants
Tice RR, Allen DG, Blackard BC, Choksi NY, Inhof CJ, Truax JF, Stokes WS. Performance of the Bovine Corneal Opacity and Permeability (BCOP) test method in detecting ocular corrosives and severe irritants. Poster presented at the 5th World Congress on Alternatives and Animal Use in the Life Sciences, Berlin, Germany, August 2005
Performance of the Hen’s Egg Test – Chorioallantoic Membrane (HET-CAM) test method in detecting ocular corrosives and severe irritants
Choksi NY, Allen DG, Blackard BC, Inhof CJ, Tice RR, Truax JF, Stokes WS. Performance of the Hen’s Egg Test – Chorioallantoic Membrane (HET-CAM) test method in detecting ocular corrosives and severe irritants. Poster presented at the 5th World Congress on Alternatives and Animal Use in the Life Sciences, Berlin, Germany, August 2005