Publications
Toxicology (397 POSTS)
2009 (6 POSTS)
Genetic pathways to colorectal cancer
Lea IA, Jackson MA, Dunnick JK. 2009. Genetic pathways to colorectal cancer. Mutat Res 670(1–2):96–98; doi: 10.1016/j.mrfmmm.2009.06.011.
View AbstractAccounting for stereo-isomers and ionization in a PBPK/PD model of VX exposure
Covington TR, Jakubowski EM, McGuire JM, Evans RA, Hulet SW, Gearhart JM. Accounting for stereo-isomers and ionization in a PBPK/PD model of VX exposure. Poster presented at the Society of Toxicology Annual Meeting, Baltimore, MD, March 2009.
2008 (3 POSTS)
Physiologically-based pharmacokinetic/pharmacodynamic (PBPK/PD) modeling of VX exposure through various routes to multiple species
Covington TR, Gearhart JM, Jakubowski EM, McGuire JM, Evans RA, Hulet SW. Physiologically-based pharmacokinetic/pharmacodynamic (PBPK/PD) modeling of VX exposure through various routes to multiple species. Poster presented at the Chemical and Biological Defense Physical Science and Technology Conference, New Orleans, LA, November 2008.
Performance characteristics of the local lymph node assay (llna) limit dose procedure
Stokes W, Allen D, Burns T, Choksi N, Matheson, J, Jacobs, Tice, R. Performance characteristics of the local lymph node assay (llna) limit dose procedure. Poster presented at Society of Toxicology 47th Annual Meeting, Seattle, WA, March 2008
View AbstractCrystallographic and small angle scattering studies of the bacteriophage T4 replication complex
Hinerman J. Crystallographic and small angle scattering studies of the bacteriophage T4 replication complex. Invited presentation to American Crystallographic Association Annual Meeting, Knoxville, TN, June 2008.
2007 (16 POSTS)
Toxicology
Britt JK, James RC. 2007. Toxicology. In: Kirk-Othmer Encyclopedia of Chemical Technology. John Wiley & Sons, Inc., Hoboken, NJ. pp. 201-252.
Pharmacokinetic modeling of manganese. III. Physiological approaches accounting for background and tracer kinetics
Teeguarden JG, Gearhart J, Clewell HJ III, Covington TR, Nong A, Andersen ME. 2007. Pharmacokinetic modeling of manganese. III. Physiological approaches accounting for background and tracer kinetics. J Toxicol Environ Health A 70:1515–1526.
View AbstractAlternatives to the mouse LD50 assay for botulinum toxin testing: An ICCVAM/NICEATM/ECVAM sponsored workshop
Kulpa-Eddy J, Jacobs A, Halder M, Burns T, Choksi N, Allen D, et al. Alternatives to the mouse LD50 assay for botulinum toxin testing: An ICCVAM/NICEATM/ECVAM sponsored workshop. Poster presented at the 6th World Congress on Alternatives and Animal Use in the Life Sciences, Tokyo, Japan, August 2007
Topical anesthetic pre-treatment in the Draize eye test: Impact on hazard classification
Choksi N, Haseman J, Truax J, Wnorowski G, Merkel D, Stokes W. Topical anesthetic pre-treatment in the Draize eye test: Impact on hazard classification. Poster presented at the 6th World Congress on Alternatives and Animal Use in the Life Sciences, Tokyo, Japan, August 2007.
Relationship between adverse ocular effects and their reversibility
Tice R, Allen D, Choksi N, Truax J, Stokes W. Relationship between adverse ocular effects and their reversibility. Poster presented at the 6th World Congress on Alternatives and Animal Use in the Life Sciences, Tokyo, Japan, August 2007.
Development of a neurotoxic equivalence scheme of relative potency for assessing the risk of PCB mixtures. Regul. Toxicol. Pharmacol. 48:148-170
Simon T, Britt JK and James RC. 2007. Development of a neurotoxic equivalence scheme of relative potency for assessing the risk of PCB mixtures. Regul Toxicol Pharmacol 48:148-170.
NTP-CEHR expert panel report on the reproductive and developmental toxicity of hydroxyurea
Liebelt EL, Balk SJ, Faber W, Fisher JW, Hughes CL, Lanzkron SM, Lewis KM, Marchetti F, Mehendale HM, Rogers JM, Shad AT, Skalko RG, Stanek EJ. 2007. NTP-CEHR expert panel report on the reproductive and developmental toxicity of hydroxyurea. Birth Defects Res B 80(4):259–366; doi: 10.1002/bdrb.20123.
An evaluation of early-life susceptibility and exposures to ethylene oxide
Kaetzel R, Wagner M, Sweeney L, Duggan A, Gargas M, Teta MJ. An evaluation of early-life susceptibility and exposures to ethylene oxide. Presented at the Society of Toxicology 46th Annual Meeting, Charlotte, NC, March 2007
The role of differences in expression of PPARalpha between mouse strains in pleotropic response to peroxisome proliferators
Woods CG, Burns AM, Bradford BU, Threadgill DW, Cunningham ML, Rusyn I. The role of differences in expression of PPARalpha between mouse strains in pleotropic response to peroxisome proliferators. Abstract 627, Society of Toxicology 46th Annual Meeting, Charlotte, NC, March 2007.
Regulation of the mevalonate pathway influences proliferative effects of Wy-14,643 in mouse liver
Burns AM, Woods CG, Rusyn I. Regulation of the mevalonate pathway influences proliferative effects of Wy-14,643 in mouse liver. Abstract 864, Society of Toxicology 46th Annual Meeting Charlotte, NC, March 2007.
Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM)/National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM)/European Centre for the Validation of Alternative Methods (ECVAM) workshop on alternative methods to refine, reduce, and replace the mouse LD50 assay for botulinum toxin testing
Kulpa-Eddy J, Jacobs AC, Halder M, Burns TA, Choksi NY, Allen DG, Tice RR, Stokes WS. Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM)/National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM)/European Centre for the Validation of Alternative Methods (ECVAM) workshop on alternative methods to refine, reduce, and replace the mouse LD50 assay for botulinum toxin testing. Poster presented at Society of Toxicology 46th Annual Meeting, Charlotte, NC, March 2007.
View AbstractComparison of tissue dosimetry in the mouse following chronic exposure to arsenic compounds
Gentry PR, Covington TR, Lawrence G, McDonald T, Snow ET, Germolec D, Moser G, Yager JW, Clewell HJ III. 2005. Comparison of tissue dosimetry in the mouse following chronic exposure to arsenic compounds. J Toxicol Environ Health A 68:329–351.
View AbstractThe use of Markov chain MonteCarlo uncertainty analysis to support a Public Health Goal for perchloroethylene
Covington TR, Gentry PR, Van Landingham CB, Andersen ME, Kester JE, Clewell HJ. 2007. The use of Markov chain MonteCarlo uncertainty analysis to support a Public Health Goal for perchloroethylene. Regul Toxicol Pharmacol 47(1):1–18.
View AbstractProtein-protein interactions between bacteriophage T4 helicase assembly protein and single-stranded DNA binding protein
Hinerman J, Mueser T. Protein-protein interactions between bacteriophage T4 helicase assembly protein and single-stranded DNA binding protein. Poster presented to Ohio Crystallographic Symposium Meeting, University of Toledo, Toledo, OH, fall 2007.
Vibrios in surface waters and a hypothetical scenario using EPA’s Environmental Consequence Assessment Tool (ECAT)
Perry CS. Vibrios in surface waters and a hypothetical scenario using EPA’s Environmental Consequence Assessment Tool (ECAT). Society for Risk Analysis Annual Meeting, San Antonio, TX, December 2007.