Toxicology (397 POSTS)

2010 (16 POSTS)

Characterizing uncertainty and population variability in a PBPK-PD mathematical model for the oxime HI-6

Sterner TR, Ruark CD, Covington TR, Hack CE, Gearhart JM. Characterizing uncertainty and population variability in a PBPK-PD mathematical model for the oxime HI-6. Poster presented at the Chemical and Biological Defense Science and Technology Conference, Orlando, FL, November 2010.

Route of entry model for predicting chemical warfare agent miosis

Makley M, Ruark C, Covington T, Robinson P, Gearhart J. Route of entry model for predicting chemical warfare agent miosis. Poster presented at the Chemical and Biological Defense Science and Technology Conference, Orlando, FL, November 2010.

The human AHR: identification of single nucleotide polymorphisms from six ethnic populations

Rowlands CJ, Staskal DF, Gollapudi B, Budinsky R. 2010. The human AHR: Identification of single nucleotide polymorphisms from six ethnic populations. Pharmacogenet Genom 20(5):283-290; doi: 10.1097/fpc.0b013e32833605f8.

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REACH – A review of the regulation and technical components of registration

Panko JM, Kreider ML, Ferrara J. REACH – A review of the regulation and technical components of registration. AIHA Pittsburgh Section, Pittsburgh, PA, February, 2010.

Physical and chemical characterization of tire-related particles: Comparison of particles generated using different methodologies

Kreider ML, Panko JM, McAtee BL, Sweet LI, Finley BL. 2010. Physical and chemical characterization of tire-related particles: Comparison of particles generated using different methodologies. Sci Total Environ 408(3):652–659.

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Hypoxia and the edema syndrome: Elucidation of a mechanism of teratogenesis

Chernoff N, Rogers JM. 2010. Hypoxia and the edema syndrome: Elucidation of a mechanism of teratogenesis. Birth Defects Res B 89(4):300–303; doi: 10.1002/bdrb.20258.

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An updated history of the Teratology Society

Shepard TH, Barr M Jr, Brent RL, Hendrickx A, Kochhar D, Oakley G, Scott WJ Jr, Rogers JM. 2010. An updated history of the Teratology Society. Birth Defects Res A 88(5):263–285; doi: 10.1002/bdra.20669.

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Organic carbon effect on nitrifying bacteria in a mixed culture

Racz L, Datta T, Goel RK. 2010. Organic carbon effect on nitrifying bacteria in a mixed culture. Water Sci Technol 61(11):2951–2956; doi: 10.2166/wst.2010.061.

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A multi-species and -route, ion- and isomer-specific physiologically-based pharmacokinetic-pharmacodynamic model for VX

Covington T, Jakubowski E, McGuire J, Byers C, Evans R, Hulet S, Whalley C, Lumley L, Clarkson E, Gearhart J. A multi-species and -route, ion- and isomer-specific physiologically-based pharmacokinetic-pharmacodynamic model for VX. Poster presented at the Bioscience Review Conference, Baltimore, MD, May 2010.

A different approach to validating screening assays for developmental toxicity

Daston GP, Chapin R, Scialli AR, Piersma AH, Carney EW, Rogers JM, Friedman JM. 2010. A different approach to validating screening assays for developmental toxicity. Birth Defects Res B 89(6):526–530. doi: 10.1002/bdrb.20276.

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A physiologically based pharmacokinetic model for pralidoxime in the guinea pig and human

Yu KO, Ruark CD, Hack CE, Sterner TR, Covington TR, Gearhart JM. A physiologically based pharmacokinetic model for pralidoxime in the guinea pig and human. Poster presented at the Society of Toxicology Annual Meeting, Salt Lake City, UT, March 2010.

Quantitative modeling in noncancer risk assessment

Zhao QJ, Haber L, Kohrman-Vincent M, Nance P, Dourson M. 2010. Quantitative modeling in noncancer risk assessment. In: Krishnan K, Andersen ME (eds), Quantitative modeling in toxicology. John Wiley & Sons Ltd.

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Human chemosensory perception of methyl isothiocyanate: Odor and chemesthesis

Cain WS, Dourson ML, Kohrman-Vincent MJ, Allen BC. 2010. Human chemosensory perception of methyl isothiocyanate: Odor and chemesthesis. Regul Toxicol Pharmacol 58(2):173–180; doi: 10.1016/j.yrtph.2010.06.018.

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Discovery of INCB9471, a potent, selective, and orally bioavailable CCR5 antagonist with potent anti-HIV-1 activity

Xue C-B, Chen L, Cao G, … Keller D, et al. 2010. Discovery of INCB9471, a potent, selective, and orally bioavailable CCR5 antagonist with potent anti-HIV-1 activity. ACS Med Chem Lett 1(9):483–487, doi: 10.1021/ml1001536.

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Structural analysis of bacteriophage T4 DNA replication: Review in the Virology Journal series on bacteriophage T4 and its relatives

Mueser TC, Hinerman JM, Devos JM, Boyer RA, Williams KJ. 2010. Structural analysis of bacteriophage T4 DNA replication: Review in the Virology Journal series on bacteriophage T4 and its relatives. Virol J 7:359.

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Geostatistical estimation of soil PCDD/F TEQ using sequential Gaussian simulation and the aggregation of results in Midland, MI

Tachovsky JA, Haws L. Geostatistical estimation of soil PCDD/F TEQ using sequential Gaussian simulation and the aggregation of results in Midland, MI. Presented at the Society for Risk Analysis Annual Meeting, Salt Lake City, UT, December 2010.

2009 (6 POSTS)

A physiologically based pharmacokinetic model for pralidoxime in the guinea pig and in human

Yu K, Covington T, Ruark C, Sterner T, Hack E, Gearhart J. A physiologically based pharmacokinetic model for pralidoxime in the guinea pig and in human. Presentation at the Chemical and Biological Defense Science and Technology Conference, Dallas, TX, November 2009.

Progress on a BEEL Guide for d-limonene

Panko JM. Progress on a BEEL Guide for d-limonene. Roundtable #224, American Industrial Hygiene Conference and Exhibition, Toronto, ON, June 2009.

Analysis methodology of rubber fraction in fine particles

Harada M, Shibata T, Panko JM, Unice KM. Analysis methodology of rubber fraction in fine particles. ACS Rubber Division 176th Technical Meeting, Pittsburgh, PA, October 2009.

The European Union’s REACH Regulation: A review of its history and requirements

Williams ES, Panko JM, Paustenbach DJ. 2009. The European Union’s REACH Regulation: A review of its history and requirements. Crit Rev Toxicol 39(7):553–575; doi: 10.1080/10408440903036056.

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