Toxicology (397 POSTS)

2013 (6 POSTS)

A physiologically based pharmacokinetic model for theoxime TMB-4: Simulation of rodent and human data

Sterner TR, Ruark CD, Covington TR, Yu KO, Gearhart JM. 2013. A physiologically based pharmacokinetic model for theoxime TMB-4: Simulation of rodent and human data. Arch Toxicol 87:661680.

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2012 (8 POSTS)

Effects of subacute inhalation exposure to tire and road wear particles in rats

Kreider ML, Panko JM, Finley BL. 2012. Effects of subacute inhalation exposure to tire and road wear particles in rats. Presented at the 2012 Health Effects Institute (HEI) Annual Conference, Chicago, IL, April 15–17, 2012.

Future trends in risk management: Control banding and REACH

Sahmel J, Cowan DM, Panko JM, Paustenbach DJ. 2012. Future trends in risk management: Control banding and REACH. Chapter 19 in: Perkins J, Gray C. (eds). Modern Industrial Hygiene, Volume III: Control of Chemical Agents, Part IV: Risk Management. ACGIH, Cincinnati, OH, pp. 727–764.

Fate of selected estrogens in two laboratory scale sequencing batch reactors fed with different organic carbon sources

Racz L, Muller JG, Goel RK. 2012. Fate of selected estrogens in two laboratory scale sequencing batch reactors fed with different organic carbon sources. Bioresource Technol 110(April):35–41; doi: 10.1016/j.biortech.2012.01.059.

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Critical review of dose-response options for F344 rat mammary tumors for acrylamide – additional insights based on mode of action

Maier A, Kohrman-Vincent M, Hertzberg R, Allen B, Haber LT, Dourson M. 2012. Critical review of dose-response options for F344 rat mammary tumors for acrylamide – additional insights based on mode of action. Food Chem Toxicol 50(5):1763–1776.

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Receptor conformations involved in dopamine D2L receptor functional selectivity induced by selected transmembrane 5 serine mutations

Fowler, JC, Bhattacharya S, Urban JD, Vaidehi N, Mailman RB. 2012. Receptor conformations involved in dopamine D2L receptor functional selectivity induced by selected transmembrane 5 serine mutations. Mol Pharmacol 81(6):820-831; doi: 10.1124/mol.111.075457.

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Risk communication for the Toxic Release Inventory

Lynch M, Brown L, Chun A, Reid J, Russel P. Risk communication for the Toxic Release Inventory. Poster presentation to Society for Risk Analysis, 2012.

Identification and characterization of adverse effects in 21st century toxicology

Keller DA, Juberg DR, Catlin N, Farland WH, Hess FG, Wolf DC, Doerrer NG. 2012. Identification and characterization of adverse effects in 21st century toxicology. Toxicol Sci 126(2):291–297, doi: 10.1093/toxsci/kfr350.

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Models for the binary complex of bacteriophage T4 Gp59 helicase loading protein: G32 single-stranded DNA-binding protein and ternary complex with pseudo-Y junction DNA

Hinerman JM, Dignam JD, Mueser T. 2012. Models for the binary complex of bacteriophage T4 Gp59 helicase loading protein: G32 single-stranded DNA-binding protein and ternary complex with pseudo-Y junction DNA. J Biol Chem 287(22):8608–8617; doi: 10.1074/jbc.M111.333476.

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2011 (11 POSTS)

Monte Carlo and sensitivity analyses of a PBPK model for the oxime TMB-4

Sterner T, Ruark C, Covington T, Gearhart J. Monte Carlo and sensitivity analyses of a PBPK model for the oxime TMB-4. Poster presented at the Chemical and Biological Defense Science and Technology Conference, Las Vegas, NV, November 2011.

Maternal toxicity and its impact on study design and data interpretation

Beyer BK, Chernoff N, Danielsson BR, Davis K -Bruno, Harrouk W, Hood RD, Janer G, Wändel Liminga U, Kim J, Rocca M, Rogers JM, Scialli AR. 2011. Maternal toxicity and its impact on study design and data interpretation. Birth Defects Res B 92(1):36–51; doi: 10.1002/bdrb.20281.

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Maternal influences on epigenetic programming of the developing hypothalamic-pituitary-adrenal axis

Grace CE, Kim SJ, Rogers JM. 2011. Maternal influences on epigenetic programming of the developing hypothalamic-pituitary-adrenal axis. Birth Defects Res A 91:797–805; doi: 10.1002/bdra.20824.

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An evaluation of single nucleotide polymorphisms in the human aryl hydrocarbon receptor-interacting protein (AIP) gene

Rowlands JC, Urban JD, Wikoff DS, Budinsky RA. 2011. An evaluation of single nucleotide polymorphisms in the human aryl hydrocarbon receptor-interacting protein (AIP) gene. Drug Metab Pharmacokinet 26(4):431-439; doi: 10.2133/dmpk.DMPK-11-SC-013.

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Seasonal variations of nitrifying community in trickling filter-solids contact (TF/SC) activated sludge systems

Datta T, Racz L, Kotay SM, Goel R. 2011. Seasonal variations of nitrifying community in trickling filter-solids contact (TF/SC) activated sludge systems. Bioresource Technol 102(3):2272–2279; doi: 10.1016/j.biortech.2010.10.043.

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An evaluation of single nucleotide polymorphisms in the human aryl hydrocarbon receptor nuclear translocator gene

Budinsky R, Urban J, Rowlands JC. 2011. An evaluation of single nucleotide polymorphisms in the human aryl hydrocarbon receptor nuclear translocator gene. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.

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Determining the mechanism of activation of glycoprotein VI

Hinerman J, Herr A. Determining the mechanism of activation of glycoprotein VI. Poster presented to the Ohio Valley Crystallographic Symposium Meeting, Cleveland, OH, November 2011.

Recognition of DNA by the helix-turn-helix global regulatory protein Lrp is modulated by the amino terminus

Hart BR, Mishra PK, Lintner RE, Hinerman JM, Herr AB, Blumenthal RM. 2011. Recognition of DNA by the helix-turn-helix global regulatory protein Lrp is modulated by the amino terminus. J Bacteriol 193(15):3794–3803.

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High prevalence of AIP gene mutations following focused screening in young patients with sporadic pituitary macroadenomas

Tichomirowa MA, Bariler A, Daly AF, Jaffrain-Rea M-L, Ronchi CL, Yaneva M, Urban JD, Petrossians P, et al. 2011. High prevalence of AIP gene mutations following focused screening in young patients with sporadic pituitary macroadenomas. Eur J Endocrinol 165(4):509-515; doi: 10.1530/EJE-11-0304.

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Single nucleotide polymorphisms in the human aryl hydrocarbon receptor nuclear translocator (ARNT) gene

Urban JD, Rowlands JC, Budinsky RA. 2011. Single nucleotide polymorphisms in the human aryl hydrocarbon receptor nuclear translocator (ARNT) gene. Drug Metab Pharmacokinet 26(6):637-645; doi: 10.2133/dmpk.DMPK-11-SC-031.

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Single nucleotide polymorphisms in the human aryl hydrocarbon receptor interacting protein (AIP) gene from six ethnic populations

Staskal-Wikoff D, Budinsky R, Rowlands JC. Single nucleotide polymorphisms in the human aryl hydrocarbon receptor interacting protein (AIP) gene from six ethnic populations. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.

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