Toxicology (397 POSTS)

2014 (21 POSTS)

Toxicology-based cancer causation analysis of CoCr-containing hip implants: A quantitative assessment of genotoxicity and tumorigenicity studies

Christian WV, Oliver LD, Paustenbach DJ, Kreider ML, Finley BL. 2014. Toxicology-based cancer causation analysis of CoCr-containing hip implants: A quantitative assessment of genotoxicity and tumorigenicity studies. J Appl Toxicol 34(9):939–967.

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Evaluation of four a-diketones for toll-like receptor-4 (TLR-4) activation in a human transfected cell line

Kerger BD, Thuett KA, Finley BL. 2014. Evaluation of four a-diketones for toll-like receptor-4 (TLR-4) activation in a human transfected cell line. Food Chem Toxicol 74:117–119.

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Design, synthesis, and evaluation of conformationally restricted acetanilides as potent and selective β3 adrenergic receptor agonists for the treatment of overactive bladder

Moyes CR, Berger R, Goble SD, Harper B, Shen DM, Wang L, … Dingley KH, et al. 2014. Design, synthesis, and evaluation of conformationally restricted acetanilides as potent and selective β3 adrenergic receptor agonists for the treatment of overactive bladder. J Med Chem 57(4):1437–1453; doi: 10.1021/jm4017224. PMID: 24437735.

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Comments on recent discussions providing differing causation methodologies

James RC, Britt J, Halmes N, Guzelian P. 2014. Comments on recent discussions providing differing causation methodologies. Hum Experim Toxicol 33(1):109-112; doi: 10.1177/0960327113491511.

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Fate of malathion and a phosphonic acid in activated sludge with varying solids retention times

Janeczko AK, Walters EB, Schuldt SJ, Magnuson ML, Willison SW, Brown LM, Ruiz ON, Felker DL, Racz L. 2014. Fate of malathion and a phosphonic acid in activated sludge with varying solids retention times. Water Res 57(15 June):127–139; doi: 10.1016/j.watres.2014.03.031.

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Evaluation of activated sludge for biodegradation of propylene glycol as an aircraft deicing fluid

Delorit JD, Racz L. 2014. Evaluation of activated sludge for biodegradation of propylene glycol as an aircraft deicing fluid. Water Environ Res 86(4):366–371; doi: 10.2175/106143013X13807328848171.

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Detecting recalcitrant organic chemicals in water with microbial fuel cells and artificial neural networks

King ST, Sylvander M, Kheperu M, Racz L, Harper WF. 2014. Detecting recalcitrant organic chemicals in water with microbial fuel cells and artificial neural networks. Sci Tot Environ 497–498(Nov):527–533; doi: 10.1016/j.scitotenv.2014.07.108.

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Using zebrafish to define mechanisms of lead (Pb) developmental neurotoxicity

Wirbisky SE, Freeman JL. 2014. Using zebrafish to define mechanisms of lead (Pb) developmental neurotoxicity. Chapter 11 in: Lessman CA, Carver EA (eds), Zebrafish: Topics in Reproduction, Toxicology, and Development. Nova Science Pub Inc., 225–244.

The impact of recent advances in research on arsenic cancer risk assessment

Gentry R, Clewell H, Greene T, Franzen A, Yager J. 2014. The impact of recent advances in research on arsenic cancer risk assessment. Regul Toxicol Pharmacol 69(1):91–104.

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A PBPK model of hypobaric and hyperbaric toluene exposure

Hack CE, Covington TR, Robinson PJ, Shiyanov PA, Mahle DA, Gearhart JM. A PBPK model of hypobaric and hyperbaric toluene exposure. Poster presented at the Society of Toxicology Annual Meeting, Phoenix, AZ, March 2014.

Methyl isothiocyanate

Gadagbui B, Vincent M, Willis A. 2014. Methyl isothiocyanate. In: Wexler, P (ed), Encyclopedia of Toxicology, 3rd ed., pp. 310–313. Elsevier.

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Mode of action analysis for liver tumors from oral 1,4-dioxane exposures and evidence-based dose response assessment

Dourson M, Reichard J, Nance P, Burleigh-Flayer H, Parker A, Vincent M, McConnell EE. 2014. Mode of action analysis for liver tumors from oral 1,4-dioxane exposures and evidence-based dose response assessment. Regul Toxicol Pharmacol 68(3):387–401.

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Integrating asthma hazard characterization methods for consumer products

Maier A, Vincent MJ, Gadagbui B, Patterson J, Beckett W, Dalton P, et al. 2014. Integrating asthma hazard characterization methods for consumer products. Regul Toxicol Pharmacol 70(1):37–45.

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Effects of MWCNT and nitrogen-doped MWCNT in lung epithelial cells

Mihalchik AL, Porter D, Castranova V, Tsuruoka S, Endo M, Qian Y. 2014. Effects of MWCNT and nitrogen-doped MWCNT in lung epithelial cells. Presented at Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.

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Managing chemical risk through alternatives assessments: Case studies and current initiatives

Brown L, Connor E. Managing chemical risk through alternatives assessments: Case studies and current initiatives. Presentation to Society for Risk Analysis, Denver, CO, 2014.

2013 (6 POSTS)

PCB126 induced increases in metallothionein expression may be species specific and AhR dependent

Klaren WD, Robertson LW. PCB126 induced increases in metallothionein expression may be species specific and AhR dependent. Society of Toxicology, Central States Regional Chapter Annual Meeting, Ames, IA, 2013.

Risk based evaluation of the chemical constituents in hydraulic fracturing fluid using the chemical disclosure registry FracFocus

Tosiano MA, Panko JM, Scott PK. Risk based evaluation of the chemical constituents in hydraulic fracturing fluid using the chemical disclosure registry FracFocus. Poster at Society of Environmental Toxicology and Chemistry, 34th Annual Meeting, Nashville, TN, November 2013.

Does dietary copper supplementation enhance or diminish PCB126 toxicity in the rodent liver?

Lai IK*, Klaren WD*, Li M, Wels B, Simmons DL, Olivier AK, Haschek WM, Wang K, Ludewig G, and Robertson LW. 2013. Does dietary copper supplementation enhance or diminish PCB126 toxicity in the rodent liver?  Chem Res Toxicol 26(5):634–644 (*Co-First Authors); doi: 10.1021/tx400049s. PMID: 23527585.

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Peer consultation on relationship between PAC profile and toxicity of petroleum substances

Patterson J, Maier A, Kohrman-Vincent M, Dourson ML. 2013. Peer consultation on relationship between PAC profile and toxicity of petroleum substances. Regul Toxicol Pharmacol 67:S86–S93.

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A framework to assess aflatoxin public health impacts in developing countries with application to Nigeria and Tanzania

Belova A, Narayan T, Brown L, Haskell J, Bozeman S, Lamb J. A framework to assess aflatoxin public health impacts in developing countries with application to Nigeria and Tanzania. Presentation to Society for Risk Analysis, Baltimore, MD, 2013.