Publications
Haws, Laurie Couture, Ph.D., DABT (223 POSTS)
2014 (8 POSTS)
X-ray fluorescence microspectroscopic analysis of duodenal mucosae following Cr(VI) exposure in drinking water
Thompson CM, Proctor DM, Suh M, Wolf JC, Haws LC, Seiter JM, Chappell MA, Harris MA. X-ray fluorescence microspectroscopic analysis of duodenal mucosae following Cr(VI) exposure in drinking water. Presented at Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.
View AbstractDevelopment of an oral cancer slope factor and lifetime average daily dose estimates for TBBPA
Wikoff D, Thompson C, Perry C, White M, Fitzgerald L, Borghoff S, Haws LC. Development of an oral cancer slope factor and lifetime average daily dose estimates for TBBPA. Presented at Society of Toxicology 53rd Annual Meeting, Phoenix, AZ, March 2014.
View AbstractEvaluation of impact of shale gas operations in the Barnett Shale region on volatile organic compounds in air and potential human health risks
Bunch AG, Perry CS, Abraham L, Wikoff DS, Tachovsky JA, Hixon JG, Urban JD, Harris MA, Haws LC. 2014. Evaluation of impact of shale gas operations in the Barnett Shale region on volatile organic compounds in air and potential human health risks. Sci Tot Environ 468-469(Jan 15):832-842; doi: 10.1016/j.scitotenv.2013.08.080. PMID: 24076504.
View AbstractA review of background dioxin concentrations in urban/suburban and rural soils across the United States: Implications for site assessments and the establishment of soil cleanup levels
Urban JD, Wikoff DS, Bunch ATG, Harris MA, Haws LC. 2014. A review of background dioxin concentrations in urban/suburban and rural soils across the United States: Implications for site assessments and the establishment of soil cleanup levels. Sci Tot Environ 466-467:(Jan 1)586-597; doi: 10.1016/j.scitotenv.2013.07.065.
View AbstractA chronic oral reference dose for hexavalent chromium-induced intestinal cancer
Thompson CM, Kirman CR, Proctor DM, Haws LC, Suh M, Hays S, Hixon JG, Harris MA. 2014. A chronic oral reference dose for hexavalent chromium-induced intestinal cancer. J Appl Toxicol 34:525-536. doi: 10.1002/jat.2907.
View AbstractHigh concentrations of hexavalent chromium in drinking water alter iron homeostasis in F344 rats and B6C3F1 mice
Suh M, Thompson C, Kirman C, Carakostas M, Haws LC, Harris M, Proctor D. 2014. High concentrations of hexavalent chromium in drinking water alter iron homeostasis in F344 rats and B6C3F1 mice. Food Chem Toxicol 65:381-388; doi: 10.1016/j.fct.2014.01.009.
View Abstract2013 (11 POSTS)
Physiologically based pharmacokinetic model for humans orally exposed to chromium
Kirman CR, Aylward LL, Suh M, Harris MA, Thompson CM, Haws LC, Proctor DM, Lin SS, Parker W, Hays SM. 2013. Physiologically based pharmacokinetic model for humans orally exposed to chromium. Chem Biol Interact 204(1):13-27; doi: 10.1016/j.cbi.2013.04.003.
View AbstractThe importance of problem formulations in risk assessment: A case study involving dioxin-contaminated soil
Dourson ML, Gadagbui B, Griffin S, Garabrant DH, Haws LC, Kirman C, Tohyama C. 2013. The importance of problem formulations in risk assessment: A case study involving dioxin-contaminated soil. Regul Toxicol Pharmacol 66(2):208-216; doi: 10.1016/j.yrtph.2013.03.010.
View AbstractAssessment of K-Ras mutant frequency and micronucleus incidence in the mouse duodenum following 90-days of exposure to Cr(VI) in drinking water
O’Brien T, Ding H, Suh M, Thompson C, Parsons BL, Harris MA, Winkelman WA, Wolf JC, Hixon JG, Schwartz AM, Myers MB, Haws LC, Proctor DM. 2013. Assessment of K-Ras mutant frequency and micronucleus incidence in the mouse duodenum following 90-days of exposure to Cr(VI) in drinking water. Mutat Res 754:15-21. doi: 10.1016/j.mrgentox.2013.03.008.
View AbstractHealth-based framework for evaluating the safety of hydraulic fracturing products
Wikoff D, Fitzgerald L, Haws L, Harris M. Health-based framework for evaluating the safety of hydraulic fracturing products. Presented at Society of Toxicology 52nd Annual Meeting, San Antonio, TX, March 2013.
View AbstractAssessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans
Thompson CM, Proctor DM, Suh M, Haws LC, Kirman CR, Harris MA. 2013. Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans. Crit Rev Toxicol 43(3):244-274; doi: 10.3109/10408444.2013.768596.
View AbstractPotential involvement of oxidative stress and iron disturbance in the development of oral cavity tumors in rats exposed to hexavalent chromium
Suh M, Thompson CM, Hixon JG, Harris MA, Kirman CR, Hays S, Haws LC, Proctor DM. 2013. Potential involvement of oxidative stress and iron disturbance in the development of oral cavity tumors in rats exposed to hexavalent chromium. Presented at the Society of Toxicology’s 52nd Annual Meeting, March 10-14, San Antonio, TX.
View AbstractDevelopment of weighted distributions of relative potency estimates for dioxin-like compounds
Haws L, Hixon G, DeVito M, Walker N, Kuriakose L, Harris M, Birnbaum L, Wikoff D. Development of weighted distributions of relative potency estimates for dioxin-like compounds. Presented at Society of Toxicology 52nd Annual Meeting, San Antonio, TX, March 2013.
View AbstractDevelopment of an oral cancer slope factor for acrylamide based on tumors relevant to humans
Urban JD, Thompson CM, Deskin R, Waite M, Haws LC. 2013. Development of an oral cancer slope factor for acrylamide based on tumors relevant to humans. Presented at Society of Toxicology 52nd Annual Meeting, San Antonio, TX, March 2013.
View AbstractA chronic oral reference dose for hexavalent chromium
Thompson CM, Kirman CR, Proctor DM, Suh M, Hays SM, Haws LC, Harris MA. A chronic oral reference dose for hexavalent chromium. Presented at Society of Toxicology 52nd Annual Meeting, San Antonio, TX, March 2013.
View AbstractDevelopment of a chronic noncancer oral reference dose and drinking water screening level for sulfolane using benchmark dose modeling
Thompson CM, Gaylor DW, Tachovsky JA, Perry C, Carakostas MC, Haws LC. 2013. Development of a chronic noncancer oral reference dose and drinking water screening level for sulfolane using benchmark dose modeling. J Appl Toxicol 33(12):1395-1406; doi: 10.1002/jat.2799.
View AbstractUsing PBPK modeling to address diurnal variation and age differences in hexavalent chromium toxicokinetics in humans
Kirman CR, Thompson CM, Proctor DM, Suh M, Haws LC, Harris MA, Hays SM. Using PBPK modeling to address diurnal variation and age differences in hexavalent chromium toxicokinetics in humans. Presented at Society of Toxicology 52nd Annual Meeting,San Antonio, TX, March 2013.
View Abstract2012 (12 POSTS)
Physiologically based pharmacokinetic model for rats and mice orally exposed to chromium
Kirman CR, Hays SM, Aylward LL, Suh M, Harris MA, Thompson CM, Haws LC, Proctor DM. 2012. Physiologically based pharmacokinetic model for rats and mice orally exposed to chromium. Chem Biol Interact 200(1):45-64; doi: 10.1016/j.cbi.2012.08.016.
View AbstractGenome-wide gene expression effects in B6C3F1 mouse intestinal epithelia following 7 and 90 days of exposure to hexavalent chromium in drinking water
Kopec AK, Kim S, Forgacs AL, Zacharewski TR, Proctor DM, Harris MA, Haws LC, Thompson CM. 2012. Genome-wide gene expression effects in B6C3F1 mouse intestinal epithelia following 7 and 90 days of exposure to hexavalent chromium in drinking water. Toxicol Appl Pharmacol 259(1):13-26; doi: 10.1016/j.taap.2011.11.012.
View AbstractAssessment of genotoxic potential of Cr(VI) in the intestine via in vivo intestinal micronucleus assay and in vitro high content analysis in differentiated and undifferentiated caco-2
Harris MA, Thompson CM, Wolf JC, Fedorov Y, Hixon JG, Proctor DM, Suh M, Haws LC. Assessment of genotoxic potential of Cr(VI) in the intestine via in vivo intestinal micronucleus assay and in vitro high content analysis in differentiated and undifferentiated caco-2. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
View Abstract