Latest News

Page 27 of 36
« First‹ Prev2526272829Next ›Last »

ToxStrategies attending and presenting at ISES – October 15-19, 2017

ToxStrategies scientist, Dr. Caroline (Carrie) Ring, will be attending and presenting at the 27th annual International Society of Exposure Science (ISES) meeting, held October 15-19, 2017, in Research Triangle Park, NC. Dr. Ring will be presenting both a poster and an oral presentation at this meeting. Characterization of total chromium and chromium-6 in UCMR3 drinking water monitoring data (TU-PO-407) Poster can be seen on Tuesday, October 17 from 10:30 – 11:00 am and 3:00 – read more…

ToxStrategies Scientists Publish Mini Review on MOA for CrVI in Drinking Water

ToxStrategies scientists have published a new mini review on the mode of action (MOA) for gastrointestinal cancers in rodents exposed to hexavalent chromium [Cr(VI)] in drinking water, in Mutation Research. This new article is an application of ten factors previously identified as important for determining whether an agent induces a tumor through a mutagenic or non-mutagenic MOA. The review focuses on in vivo research in target tissues of target species. The article concludes that Cr(VI) read more…

ToxStrategies attending and presenting at EMGS – September 9-13, 2017

ToxStrategies scientists are attending and presenting at the 48th annual Environmental Mutagenesis & Genomics Society (EMGS) meeting, held September 9-13, 2017 in Raleigh, NC.  Dr. Thompson and Dr. Rager will be presenting two posters, titled: Bridging the Gap between Carcinogenicity Studies, Mode of Action, and Exposure for Making Public Health Decisions:  Case Study with Hexavalent Chromium, and Epigenetic Trends in Response to Chemical Exposures and Relationships to Disease:  A Review on Directional Consistencies EMGS’ vision is read more…

ToxStrategies scientists attending and presenting at NIEHS Symposium – August 24-25, 2017

ToxStrategies’ scientists are attending and presenting at the 4th International Symposium on Systematic Review and Meta-Analysis of Laboratory Animal Studies, held August 24-25, 2017 at the NIEHS in Research Triangle Park.  Dr. Wikoff’s presentation, “Evaluation of Mechanistic Data Based on Key Characteristics of Carcinogens: Application of A Text Mining Tool and a Quantitative Evaluation Framework,” is part of a two-day symposium for newcomers and experts alike. The presentation is one example of how systematic review approaches read more…

ToxStrategies scientist, Dr. Carrie Ring, presenting at the Gordon Research Conference

Dr. Carrie Ring will be presenting at the Gordon Research Conference (GRC) on Cellular and Molecular Mechanisms of Toxicity, held August 13-18, 2017, in Andover, NH. The theme of this week’s conference is Advanced Investigations in Mechanistic Toxicology. Dr. Ring’s presentation (Where is the Risk? In Vitro-In Vivo Extrapolations (IVIVE) Using Reverse Toxicokinetics) will be part of a session titled, “Non-Animal Methods in Toxicology: Novel Mechanisms and New Opportunities.” Her presentation will discuss high-throughput chemical read more…

UN releases newly revised 7th edition of GHS – System of Classification and Labeling of Chemicals

In July 2017, the United Nations published revised guidelines for the classification and labeling of chemicals in the 7th edition of their Globally Harmonized System purple book, originally published in 2003.  Several minor updates were made to various health hazard outcome definitions, as well as the classification of selected flammable gases, among other changes.  The definitions of ten health hazard outcomes were updated to remove specific time periods of exposure or to allow for the read more…

ToxStrategies scientist identifies populations sensitive to environmental chemicals by simulating toxicokinetic variability

  ToxStrategies scientist Caroline L. Ring, Ph.D,, along with co-authors from the US Environmental Protection Agency, recently published the article, “Identifying populations sensitive to environmental chemicals by simulating toxicokinetic variability” in Environment International. This manuscript describes a new open-source software package to simulate inter-individual physiological variability for in vitro-in vivo extrapolation (IVIVE) of data from in vitro high-throughput toxicity screening (HTS) assays, with the aim of conducting rapid risk-based chemical prioritization for potentially sensitive sub-populations. read more…

Page 27 of 36
« First‹ Prev2526272829Next ›Last »