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The Office of Environmental Health Hazard Assessment (OEHHA) adopted substantial changes to the warning regulations under The Safe Drinking Water and Toxics Enforcement Act of 1986, commonly referred to as Proposition 65. These new regulations become effective August 30, 2018. Under the new regulations, OEHHA clarifies that the primary responsibility for providing warnings to consumers lies with the manufacturer, distributor, producer, and/or packager, rather than the retailer, except under specific circumstances. The primary responsibility of read more…

A systematic review of caffeine effects in healthy populations has been named Food and Chemical Toxicology’s Best Paper of the Year (2017). Lead author and ToxStrategies toxicologist Dr. Daniele Wikoff received the notification from Editor-in Chief Dr. José Domingo, in which he noted that the co-Editors selected their top eight favorite articles, and the full roster of Associate Editors voted to name the best overall. The seminal systematic review involved screening more than 5,000 papers, and read more…

ToxStrategies is pleased to announce the establishment of The Center of Excellence for 21st Century Toxicology (21CT). The Center will focus on supporting the transition in toxicological science to in vitro and computational toxicology through the design and implementation of 21st century methods in risk assessment. 21CT is designed to be a science hub, providing expertise in cell-based science, computational toxicology, targeted in vivo studies, pharmacokinetics, in vitro–to–in vivo extrapolation (IVIVE), rapid exposure assessment, systematic literature reviews for evidence-based toxicology, and Adverse Outcome Pathway–based safety read more…

ToxStrategies toxicologist Dr. Daniele Wikoff is a co-author with the Editor-In-Chief of Toxicological Sciences, Dr. Gary Miller, on a just-published editorial announcing the creation of a new category of manuscripts for the journal: “Systematic Review.” Toxicological Sciences seeks submissions of systematic reviews, as well as manuscripts related to methodological advances or best practices, thus facilitating the integration and evolution of evidence-based practice in toxicology. Click here to read the full editorial in Toxicological Sciences, and read more…

This month, interdisciplinary scientific experts will meet in Lyon, France, to evaluate the potential of ethyl acrylate, methyl acrylate, and 2-ethylhexly acrylate, along with other substances, to increase the risk of cancer. The findings from this evaluation will be reported in Volume 122 of the International Agency for Research on Cancer (IARC) Monographs Program. ToxStrategies recently published in the peer-reviewed literature a series of articles on these substances that are useful for integrating the relevant read more…