Latest News

ToxStrategies scientist Dr. Bill Rish is a co-author of a new article that demonstrates acceptably low doses of naturally occurring radiation (NORM) when using the waste from alumina production (APR, or alumina production residue) in producing and using cement. Putting APR to this beneficial use, instead of storing it indefinitely, has raised concerns about workers involved in cement production or use, or members of the public, being exposed to radiation. The findings of Dr. Rish read more…

A recently published article by ToxStrategies scientists, with Dr. Daniele Wikoff as lead author, presents the systematic identification, appraisal, and integration of mechanistic data in an assessment of potential carcinogenicity of the non-nutritive sweetener aspartame. Based on the evaluation of over 1300 measurements/assay endpoints related to one or more key characteristics of carcinogens (KCC) reported in the literature and via high-throughput screening data, the authors found a lack of evidence for activity across the mechanistic read more…

ToxStrategies was excited to exhibit, for the first time, at Supply Side West (SSW) on October 17 and 18, in Las Vegas. According to the trade association Food ingredients North America, more than 17,000 ingredient buyers and suppliers from the dietary supplement, food, beverage, personal care, and sports nutrition industries  attended SSW to learn about new trends and science from over 1,300 exhibitors and 140 hours of educational and conference programming. ToxStrategies has a reputation read more…

Following implementation of the Hemp Farming Act, part of the Agricultural Improvement Act of 2018 (aka, “2018 Farm Bill”), interest in hemp-derived products, especially cannabidiol (CBD), has outpaced the development of a legal pathway for their use. As the industry advocates for the US FDA to issue a regulation for lawful marketing of CBD in food and/or dietary supplements, ToxStrategies has been assisting clients in conducting systematic safety evaluations, including those to support future regulatory read more…

ToxStrategies scientists have published an article proposing an oral reference dose (RfD) for the per‐ and polyfluoroalkyl substance (PFAS) commonly known to as GenX. The new proposed value differs from those put forth by many regulatory agencies. The assessment relies on mechanistic data to show that many of the effects observed in rodents involve PPARa, which is well recognized to exhibit differential responses in rodents and humans. Using updated histopathological nomenclature, liver effects in mice read more…

On August 1, 2019, the U.S. EPA announced a new website where visitors can view and search monthly updates for any active Premanufacture Notices (PMNs), Significant New Use Notices (SNUNs), and Microbial Commercial Activity Notice (MCANs) that may be of interest (searchable by case number). The site is named, “Statistics for the New Chemicals Review Program under TSCA.” Users can download a spreadsheet with a list of all active cases and the current status of read more…

ToxStrategies has announced an opening for a Scientist III or Senior Scientist. Specifically, the firm seeks a toxicologist (or similar discipline) with experience conducting systematic reviews to join our expanding Health Science consulting practice. The position involves application of these approaches to hazard- and risk-based evaluations of foods, chemicals, and consumer products. The successful candidate will have a working knowledge of systematic review concepts, as well as expertise in systematic review tools such as DistillerSR. read more…

Ms. Seneca Fitch, ToxStrategies scientist, has been invited by the Evidence-Based Toxicology Collaboration (EBTC) Board of Trustees at Johns Hopkins Bloomberg School of Public Health to join the Scientific Advisory Council. In this role, she will serve a 3-year term in addition to her ongoing involvement within the organization’s Tox21 working group. The EBTC SAC is an international group of scientists from a variety of organizations, including government agencies, NGOs, industry, and academia. Members provide read more…