The USEPA has released their draft Risk Evaluation for Trichloroethylene (TCE) for public comment. TCE is the eighth of the first ten chemicals to undergo risk evaluation under amended TSCA. The TCE draft risk evaluation and supporting documents can be found at: https://www.epa.gov/assessing-and-managing-chemicals-under-tsca/draft-risk-evaluation-trichloroethylene.
The Environmental Protection Agency has finalized low-priority designations for 20 substances under the Toxic Substances Control Act, and will not subject them to risk evaluations. “This final list of low-priority chemicals will allow EPA to focus its risk evaluation efforts on the chemicals that could significantly impact public health and the environment,” said the EPA. For more information, visit https://www.epa.gov/assessing-and-managing-chemicals-under-tsca/chemical-substances-undergoing-prioritization-low.
Engineer/Exposure Assessor ToxStrategies, Inc., is seeking a chemical or environmental engineer with experience conducting quantitative chemical exposure assessments to join our expanding Exposure Sciences consulting practice. The position involves data-driven assessments of human and environmental exposure to chemicals to support risk-based evaluations related to foods, manufacturing of chemical substances, use of commercial and consumer products and contaminated sites. The successful candidate will have a working knowledge of statistical approaches for evaluation of environmental data (including read more…
ToxStrategies scientists attended the 44th Annual Winter Meeting of the Toxicology Forum January 27–29, where they presented on a wide range of topics, including the use of New Approach Methods (NAMs) in the risk characterization of PFAS; advances, opportunities, and challenges in using NAMs in toxicological evaluations; expanding the use and chemical space of the TTC; and challenges and opportunities in assessing the safety of sunscreen active ingredients. The following ToxStrategies scientists were participants read more…
For nearly six decades, the Joint FAO/WHO Expert Committee on Food Additives (JECFA) and the Joint FAO/WHO Meeting on Pesticide Residues (JMPR) have served as scientific advisory bodies to the Codex Alimentarius Commission. In light of the increasingly complex nature of chemical assessments in food since publication of the latest guidance in 2009, JECFA/JMPR have initiated multiple efforts to update subchapters in EHC 240 (Principles and methods for the risk assessment of chemicals in food, read more…
Dr. Susan Borghoff, Director of ToxStrategies’ Center of Excellence for 21st Century Toxicology, was invited to participate in the inaugural Conference on Reducing Animal Testing for Chemical Safety, convened on December 17, 2019, by EPA’s Office of Pesticide Programs. Approximately 60 scientists from government, academia, and industry were present at the full-day meeting, and were joined by more than 600 individuals in the morning session via teleconference. The gathered experts in environmental and chemical safety read more…
A recently published article by ToxStrategies scientists and others presents the systematic identification, appraisal, and integration of mechanistic data in an assessment of potential carcinogenicity of the non-nutritive sweetener sucralose. Based on the evaluation of over 700 measurements/assay endpoints related to one or more key characteristics of carcinogens (KCC) reported in the literature and via high-throughput screening data, the authors found a lack of evidence for activity across the mechanistic database. These results align with the read more…
EpidStrategies, a division of ToxStrategies Inc., is founded on rigorous scientific principles that guide our research on complex health conditions. We are scientists who provide consulting services to public and private sectors worldwide. With a focus on pharmaceuticals, medical devices, nutrition, and environmental chemicals, our scientists aid clients in the conduct, evaluation, and interpretation of epidemiologic studies. We are seeking an epidemiologist to join our team of epidemiologists and statisticians conducting systematic literature reviews and read more…
