Julie Panko presents workshop at SOT 2021
ToxStrategies scientist, Julie Panko, CIH, will present a workshop at The Society of Toxicology’s virtual meeting. The workshop session is titled, Challenges in Characterizing Environmental Health Risk of Microplastics: Experiences from the Tire Industry Project Related to Tire and Road Wear Particles, and will take place Monday, March 22nd, from 11:15 to 11:35 ET. Ms. Panko’s presentation is part of the main session, titled, Tackling the Potential Human Health Impacts of Microplastics and Nanoplastics: Challenges for Toxicologists in the Assessment of Real-World Complex Mixtures. You can join the workshop here.
New study of steviol glycosides indicates lack of carcinogenicity
An article published recently by ToxStrategies scientists presents the systematic identification, appraisal, and integration of mechanistic data in an assessment of the potential carcinogenicity of steviol glycosides, a naturally occurring, non-nutritive sweetener. Based on an evaluation of more than 900 measurements/assay endpoints related to one or more key characteristics of carcinogens (KCC) reported in the literature or within the ToxCast/Tox21 high-throughput screening data, the authors found a lack of evidence for activity across the mechanistic database. The assessment included individual steviol glycosides, as well as mixtures such as whole stevia leaf extracts. read more…
New article encourages diligence in classifying chemicals’ carcinogenicity
BHA (butylated hydroxyanisole) is one of many synthetic antioxidants used in food, food packaging, pharmaceuticals, and cosmetics. Since 1947, BHA has been added to fat-containing foods as an antioxidant to preserve the food and prevent the loss of certain vitamins. However, the International Agency for Research on Cancer (IARC) has classified BHA as “possibly carcinogenic to humans,” because it was linked to tumor formation in rats exposed to high levels. IARC later determined that the read more…
ToxStrategies presents at SOT 2021
ToxStrategies scientists have the following posters available for viewing via The Society of Toxicology’s virtual meeting platform, March 12th through May 31st, as well as live poster sessions for direct questions and answers. Please click on the poster image to view the full abstract and live session information. Ms. Deborah Proctor: Improving the Inhalation Cancer Risk Assessment for Hexavalent Chromium: Lung Cancer Mortality and Exposure Reconstruction of Aircraft Manufacturing Workers with Long-Term Low-Level Exposures Dr. Chad Thompson: Toward a read more…
SOT Annual Meeting & ToxExpo
The Society of Toxicology will host their virtual event on Friday, March 12th, through Friday, March 26th. The SOT virtual meeting will have three experience versions to choose from, featuring a variety of participation options. This year’s meeting includes more than 65 sessions, 1000 poster presentations, and 40 exhibitor–hosted sessions. Virtual features include SOT TV, Networking through Hallway Huddles Lounge or Tiny Tox Talks, and the SOT Hub. You can register to participate here.
Preparing for TSCA risk evaluation of metals
To date, U.S. EPA has not selected a metal as a high-priority chemical for risk evaluation under the Toxic Substances Control Act (TSCA). TSCA requires that 50% of all high-priority designations be drawn from the 2014 Update of the TSCA Work Plan and that EPA also gives preference to Work Plan chemicals with the following characteristics: 1) Persistence and bioaccumulation scores of three; 2) Known human carcinogens; or 3) High acute or chronic toxicity. The 2014 read more…
New studies published on formaldehyde health effects
ToxStrategies scientists Dr. Chad Thompson, Dr. Allison Franzen, and Ms. Seneca Fitch and their colleagues have published a pair of papers in a special issue of Critical Reviews in Toxicology that celebrates the journal’s 50th anniversary. The two articles focus on the modes of action (MOAs) by which exposure to formaldehyde is related to leukemia and nasal cancer. The topics are timely, in light of USEPA’s designation of formaldehyde as a high-priority substance under the Toxic Substances Control Act. With regard to leukemia, the research consisted read more…
Dr. Laurie Haws on Science Panel at ARA workshop
Dr. Laurie Haws will be participating on the Science Panel at the upcoming Alliance for Risk Assessment (ARA) workshop, Beyond Science & Decisions: From Problem Formulation to Dose-Response Assessment. The workshop aims to showcase practical, problem-driven approaches for “fit–for–purpose” risk assessments and will be held virtually on February 24–25. ARA’s Beyond Science & Decisions workshops underscore the importance of using novel and evolving scientific methods and approaches to address specific problems faced by risk assessors and risk managers in a variety of organizations. The workshop agenda is available here. Registration is now open. Register here.