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The first substantial changes to FDA’s regulatory authority over cosmetics makers and products since 1938 passed Congress in December 2022, in the form of the Modernization of Cosmetics Regulation Act (MoCRA). MoCRA culminates more than a decade of work among Congress, FDA, consumer and environmental groups, and the beauty and personal care industry. With MoCRA, the cosmetics industry will soon be expected to: Maintain records, with adequate substantiation, to demonstrate that the cosmetic product is read more…

A new article published in the journal Food and Chemical Toxicology concludes that the totality of evidence does not support a link between human consumption of aspartame and occurrence of cancer, addressing recent controversy arising from animal cancer bioassay results, which were interpreted by the Ramazzini Institute as indicating such a link. ToxStrategies scientists conducted a comprehensive systematic review of the scientific literature to assess the overall findings regarding an association between aspartame consumption and read more…

EPA recognizes that there are environmentally related health inequities in certain communities, exacerbated by socioeconomic and psychological stressors, background health conditions, and ethnicity-specific susceptibilities. Environmental justice initiatives are intended to address the history of disproportionate exposure and proximity to environmental hazards in these communities. EPA and other federal and state agencies are in the process of developing and using various approaches, methods, and data to achieve a Cumulative Impact Assessment (CIA) for the environmental exposures read more…

For the 16th year, the American Feed Industry Association will hold its AFIA Pet Food Conference in conjunction with the 2023 International Production & Processing Expo (IPPE—January 24–26, in Atlanta, Georgia). The Pet Food Conference is an annual opportunity for professionals in the field to learn about new research, trends, and developments in the pet food industry. Hot topics to be discussed include sampling techniques for aflatoxin, export trends, regulatory updates, pet food sustainability, and read more…

ToxStrategies scientists Drs. Allison Franzen and Susan Borghoff are among the authors of a new paper in the journal Critical Reviews in Toxicology. The work identifies an adverse outcome pathway (AOP), for kidney tumors that occur specifically in male rats through a mode of action (MoA) that is not relevant to humans—inducing α2u-globulin nephropathy (α2u-N). The authors define both the molecular initiating event (MIE) and key events (KEs) that lead to the occurrence of kidney read more…

ToxStrategies is excited to be presenting again at The Society of Environmental Toxicology and Chemistry (SETAC) Annual Meeting, November 13th through 17th.  The meeting is available in person, located in Pittsburgh, PA, or through virtual attendance, for all registered attendees. Please click on the poster image or icon below to view the full abstract and presentation information. Jennifer Bare, B.S.: Example Framework for Chemical Additive Replacement Prioritization in a Circular Economy for Plastics: Human Health read more…