Publications

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PFAS (44 POSTS)

2020 (3 POSTS)

Assessment of the mode of action underlying the effects of GenX in mouse liver and implications for assessing human health risks

Chappell GA, Thompson CM, Wolf JC, Cullen JM, Klaunig JE, Haws LC. 2020. Assessment of the mode of action underlying the effects of GenX in mouse liver and implications for assessing human health risks. Toxicol Pathol 48(3):494–508; doi: 10.1177/0192623320905803. PMID: 32138627.

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Introduction to “Use of New Approach Methods in Risk Characterization of PFAS: Challenges and Opportunities”

Haws L (session co-chair). Introduction to “Use of New Approach Methods in Risk Characterization of PFAS: Challenges and Opportunities.” 44th Annual Winter Meeting, the Toxicology Forum, Tysons, VA, January 2020.

Assessment of the relevance of toxicological findings in the development of an oral reference dose for GenX

Thompson CM, Ring C, Pham L, Chappell GA, Haws LC. Assessment of the relevance of toxicological findings in the development of an oral reference dose for GenX. Poster for Society of Toxicology 59th Annual Meeting, Virtual, 2020.

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2019 (6 POSTS)

Development of an oral reference dose for GenX using the latest toxicological and risk assessment methodologies: Environmental risk assessment of per- and polyfluoroalkyl substances (PFAS)

Thompson C, Chappell G, Cullen J, Wolf JC, Haws L. Development of an oral reference dose for GenX using the latest toxicological and risk assessment methodologies: Environmental risk assessment of per- and polyfluoroalkyl substances (PFAS). SETAC North America Focused Topic Meeting, Durham, NC, August 2019.

Transcriptomic responses in livers of GenX-treated mice demonstrate up-regulation of PPAR signaling and related pathways

Chappell GA, Thompson CM, Wolf J, Cullen J, Haws LC. Transcriptomic responses in livers of GenX-treated mice demonstrate up-regulation of PPAR signaling and related pathways. Environmental Mutagenesis and Genomics Society, Washington, DC, September 2019.

The useful chemistry of perfluorinated compounds: Managing safety. The sticky subject of non-stick: Regulatory science challenges of per- and poly-fluorinated compounds (PFAS)

Thompson CM. The useful chemistry of perfluorinated compounds: Managing safety. The sticky subject of non-stick: Regulatory science challenges of per- and poly-fluorinated compounds (PFAS). Texas A&M University Interdisciplinary Faculty of Toxicology Training Program, 2019 Annual Regulatory Science Symposium, August 2019.

Development of an oral reference dose for the perfluorinated compound GenX

Thompson CM, Fitch SE, Ring C, Rish W, Cullen JM, Haws LC. 2019. Development of an oral reference dose for the perfluorinated compound GenX. J Appl Toxicol 39(9):1267–1282; doi: 10.1002/jat.3812.

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Prioritization of eight PFAS by population exposure and reference-dose uncertainty

Ring CL, Rish WR, Brorby GL. Prioritization of eight PFAS by population exposure and reference-dose uncertainty. Poster session at SETAC North America Focused Topic Meeting “Environmental Risk Assessment of PFAS”, Durham, NC, August 2019.

A hypothesis-driven weight-of-evidence analysis to evaluate potential endocrine disrupting properties of perfluorohexanoic acid (PFHxA)

Borghoff SJ, Fitch S, Huggett, Wikoff D. A hypothesis-driven weight-of-evidence analysis to evaluate potential endocrine disrupting properties of perfluorohexanoic acid (PFHxA). 2019. Poster at Society of Toxicology Annual Meeting, Baltimore, MD, March 2019.

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2018 (2 POSTS)

A hypothesis-driven weight-of-evidence analysis to evaluate potential endocrine activity of perfluorohexanoic acid

Borghoff SJ, Fitch S, Rager JE, Huggett D. 2018. A hypothesis-driven weight-of-evidence analysis to evaluate potential endocrine activity of perfluorohexanoic acid. Regul Toxicol Pharmacol 99(Nov):168–181; doi: 10.1016/j.yrtph.2018.09.001.

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Perfluoroalkyl Substances in the Environment: Theory, Practice and Innovation

Kempisty DM, Xing Y, Racz L (eds). 2018. Perfluoroalkyl Substances in the Environment: Theory, Practice and Innovation. Taylor and Francis CRC Press: Boca Raton, FL.

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2007 (1 POST)

A methodology for estimating human exposure to perfluorooctanoic acid (PFOA): A retrospective exposure assessment of a community (1951-2003)

Paustenbach DJ, Panko JM, Scott PK, Unice KM. 2007. A methodology for estimating human exposure to perfluorooctanoic acid (PFOA): A retrospective exposure assessment of a community (1951-2003). J Toxicol Environ Health A 70(1):28–57; doi: 10.1080/15287390600748815.

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2006 (2 POSTS)

Retrospective modeling of potential residential exposure to perfluorooctanoic acid (PFOA) releases from a manufacturing facility

Paustenbach DJ, Panko JM, Scott PK, Unice KM. Retrospective modeling of potential residential exposure to perfluorooctanoic acid (PFOA) releases from a manufacturing facility. Society of Toxicology 45th Annual Meeting, San Diego, CA, March 2006.

Effects of perfluorooctanoic acid exposure during pregnancy in the mouse

Lau C, Thibodeaux JR, Hanson RG, Narotsky MG, Rogers JM, Lindstrom AB, Strynar MJ. 2006. Effects of perfluorooctanoic acid exposure during pregnancy in the mouse. Toxicol Sci 90(2):510–518; doi: 10.1093/toxsci/kfj105.

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2005 (2 POSTS)

Effects of prenatal perfluorooctane sulfonate (PFOS) exposure on lung maturation in the perinatal rat

Grasty RC, Bjork JA, Wallace KB, Lau CS, Rogers JM. 2005. Effects of prenatal perfluorooctane sulfonate (PFOS) exposure on lung maturation in the perinatal rat. Birth Defects Res B 74(5):405–416; doi: 10.1002/bdrb.20059.

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Effects of prenatal perfluorooctanesulfonate (PFOS) exposure on lung maturation in the perinatal rat

Grasty RC, Roberts N, Klinefelter G, Bjork JA, Wallace KB, Lau CS, Rogers JM. 2005. Effects of prenatal perfluorooctanesulfonate (PFOS) exposure on lung maturation in the perinatal rat. Birth Defects Res A 73:314.

2004 (3 POSTS)

The developmental toxicity of perfluoroalkyl acids and their derivatives

Lau C, JL Butenhoff, JM Rogers. 2004. The developmental toxicity of perfluoroalkyl acids and their derivatives. Toxicol Appl Pharmacol 198(2):231-241; doi: 10.1016/j.taap.2003.11.031.

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Effects of prenatal exposure to perfluorooctane sulfonate on the developing lung in the rat

Grasty RC, Roberts N, Grey BE, Lau C, Rogers JM. Effects of prenatal exposure to perfluorooctane sulfonate on the developing lung in the rat. Society for Toxicology 43rd Annual Meeting, Baltimore, MD, March 2004.

Perfluorooctane sulfonate (PFOS) alters lung development in the neonatal rat

Grasty RC, Roberts N, Grey BE, Lau C, Rogers JM. 2004. Perfluorooctane sulfonate (PFOS) alters lung development in the neonatal rat. Birth Defects Res A 70(5):42.

2003 (4 POSTS)

Window of susceptibility to perfluorooctane sulfonate (PFOS)-induced neonatal mortality in the rat

Grasty RC, Grey BE, Lau CS, Rogers JM. 2003. Window of susceptibility to perfluorooctane sulfonate (PFOS)-induced neonatal mortality in the rat. Birth Defects Research B 68(3):5.

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