Publications

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PBPK/PBDE (50 POSTS)

2008 (7 POSTS)

Renal clearance parameters for PBPK model analysis of early lifestage differences in the disposition of environmental toxicants

DeWoskin RS, Thompson CM. 2008. Renal clearance parameters for PBPK model analysis of early lifestage differences in the disposition of environmental toxicants. Regul Toxicol Pharmacol 51(June):66–86; doi: 10.1016/j.yrtph.2008.02.005.

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A PBPK model for evaluating the impact of aldehyde dehydrogenase polymorphisms on comparative rat and human nasal tissue acetaldehyde dosimetry

Teeguarden JG, Bogdanffy MS, Covington TR, Tan C, Jarabek AM. 2008. A PBPK model for evaluating the impact of aldehyde dehydrogenase polymorphisms on comparative rat and human nasal tissue acetaldehyde dosimetry. Inhal Toxicol 20(4):375–390; doi: 10.1080/08958370801903750.

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Simulation of VX exposure in multiple species by means of a physiologically based pharmacokinetic/pharmacodynamic model

Gearhart JM, Covington TR, Robinson PJ, Whalley CE, McGuire JM, Evans RA, et al. Simulation of VX exposure in multiple species by means of a physiologically based pharmacokinetic/pharmacodynamic model. Poster presented at the Bioscience Review Conference, Baltimore, MD, May 2008.

Possible mechanisms of thyroid hormone disruption in mice by BDE 47, a major polybrominated diphenyl ether congener

Richardson VM, Staskal DF, Ross DG, Diliberto JJ, Devito MJ, Birnbaum LS. 2008. Possible mechanisms of thyroid hormone disruption in mice by BDE 47, a major polybrominated diphenyl ether congener. Toxicol Appl Pharmacol 226(3):244-250; doi: 10.1016/j.taap.2007.09.015.

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Preliminary evaluation of human health risk associated with exposure to PBDEs in the United States

Staskal DF, Tachovsky JA, Harris MA, Haws LC. 2008. Preliminary evaluation of human health risk associated with exposure to PBDEs in the United States. Presented at Dioxin 2008, August 17-22, Birmingham, England.

Principal components analysis of PBDE concentrations in fish tissue from southern Mississippi

Tachovsky JA, Staskal DF, Harris MA, Scott LF, Luksemburg WJ, Paustenbach DP, Haws LC. 2008. Principal components analysis of PBDE concentrations in fish tissue from southern Mississippi. Presented at Dioxin 2008, August 17-22, Birmingham, England.

Approaches for applications of physiologically based pharmacokinetic models in risk assessment

Thompson CM, Sonawane B, Barton HA, DeWoskin RS, Schlosser P, Lipscomb JC, Chiu W, Krishnan K. 2008. Approaches for applications of physiologically based pharmacokinetic models in risk assessment. J Toxicol Environ Health B 11(7):519–547; doi: 10.1080/10937400701724337.

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2007 (3 POSTS)

Differential urinary protein binding of PBDEs in mice

Diliberto JJ, Staskal DF, Hakk H, Birnbaum LS. Differential urinary protein binding of PBDEs in mice. Society of Toxicology 46th Annual Meeting, Charlotte, NC, March 2007.

A physiologically-based pharmacokinetic model for developmental exposure to PBDE-47 in rodents

Emond C, Raymer J, Garner E, Diliberto J, Staskal D, Birnbaum LS. A physiologically-based pharmacokinetic model for developmental exposure to PBDE-47 in rodents. Society of Toxicology 46th Annual Meeting, Charlotte, NC, March 2007.

Dietary intake of PBDEs based on consumption of catfish in southern Mississippi

Nguyen LM, Staskal DF, Ferriby LL, Williams ES, Luksemburg WJ, Haws LC, Birnbaum LS, Paustenbach DJ, Harris MA. Dietary intake of PBDEs based on consumption of catfish in southern Mississippi. Society of Toxicology 46th Annual Meeting, Charlotte, NC, March 2007.

2006 (7 POSTS)

Disposition of BDE 47 in developing mice

Staskal DF, Diliberto JJ, Birnbam LS. 2006. Disposition of BDE 47 in developing mice. Toxicol Sci 90(2):309-16; doi: 10.1093/toxsci/kfj098.

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Revised assessment of cancer risk to dichloromethane II. Application of probabilistic methods to cancer risk determinations

David RM, Clewell HJ, Gentry PR, Covington TR, Morgott DA, Marino DJ. 2006. Revised assessment of cancer risk to dichloromethane II. Application of probabilistic methods to cancer risk determinations. Regul Toxicol Pharmacol 45(1):55–65; doi: 10.1016/j.yrtph.2005.12.003.

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Revised assessment of cancer risk to dichloromethane: Part I Bayesian PBPK and dose-response modeling in mice

Marino DJ, Clewell HJ, Gentry PR, Covington TR, Hack CE, David RM, Morgott DA. 2006. Revised assessment of cancer risk to dichloromethane: Part I Bayesian PBPK and dose-response modeling in mice. Regul Toxicol Pharmacol 45(1):44–54; doi: 10.1016/j.yrtph.2005.12.007.

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Toxicokinetics of polybrominated diphenyl ether congeners 47, 99, 100, and 153 in mice

Staskal DF, Hakk H, Bauer D, Diliberto JJ, Birnbam LS. 2006. Toxicokinetics of polybrominated diphenyl ether congeners 47, 99, 100, and 153 in mice. Toxicol Sci 94(1):28-37; doi: 10.1093/toxsci/kfl091.

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Effects of BDE 47 on nuclear receptor regulated genes and implications for thyroid hormone disruption

Richardson VM, Staskal DF, Diliberto JJ, Birnbaum LS. Effects of BDE 47 on nuclear receptor regulated genes and implications for thyroid hormone disruption. Society for Toxicology 45th Annual Meeting, San Diego, CA, March 2006.

Polybrominated diphenyl ethers in southern Mississippi catfish

Staskal DF, Ferriby LL, Williams ES, Luksemburg WJ, Haws LC, Birnbaum LS, Paustenbach DJ, Harris M. 2006. Polybrominated diphenyl ethers in southern Mississippi catfish. Dioxin 2006, Oslo, Norway, August 2006.

Effect of age on the tissue distribution of BDE 47 in mice

Staskal DF, Diliberto JJ, Birnbaum LS. Effect of age on the tissue distribution of BDE 47 in mice. Society of Toxicology 45th Annual Meeting, San Diego, CA, March 2006.

2005 (4 POSTS)

Disposition of BDE 99 and BDE 153 in female mice

Bauer D, Staskal DF, Diliberto JJ, Birnbaum LS. Disposition of BDE 99 and BDE 153 in female mice. Society of Toxicology 44th Annual Meeting, New Orleans, LA, March 2005.

Evaluation of oral and intravenous route pharmacokinetics, plasma protein binding and uterine tissue dose metrics of bisphenol A: A physiologically based pharmacokinetic approach

Teeguarden JG, Waechter JM Jr, Clewell HJ 3rd, Covington TR, Barton HA. 2005. Evaluation of oral and intravenous route pharmacokinetics, plasma protein binding and uterine tissue dose metrics of bisphenol A: A physiologically based pharmacokinetic approach. Toxicol Sci 85(2):429–446; doi: 10.1093/toxsci/kfi135.

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A harmonized PBPK model for trichloroethylene risk assessment

Covington TR, Clewell HJ, Fisher JW, Keys DA, Hack C, Zhao JQ. A harmonized PBPK model for trichloroethylene risk assessment. Poster presented at the Society of Toxicology 44th Annual Meeting, New Orleans, LA, March 2005.

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