Publications
chromium (113 POSTS)
2012 (16 POSTS)
Hexavalent chromium reduction kinetics in rodent stomach contents
Proctor DM, Suh M, Aylward LL, Kirman CR, Harris MA, Thompson CM, Gürleyük H, Gerads R, Haws LC, Hays SM. 2012. Hexavalent chromium reduction kinetics in rodent stomach contents. Chemosphere 89(5):487-493; doi: 10.1016/j.chemosphere.2012.04.065.
View AbstractAssessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis
Thompson CM, Fedorov Y, Brown DD, Suh M, Proctor DM, Kuriakose L, Haws L, Harris MA. 2012. Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis. PLoS ONE 7(8):e42720; doi: 10.1371/journal.pone.0042720.
View AbstractGastric reduction of Cr(VI) in mice, rats and humans
Hays SM, Kirman C, Aylward L, Suh M, Proctor D. Gastric reduction of Cr(VI) in mice, rats and humans. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
View AbstractAssessment of genotoxic potential of Cr(VI) in the mouse duodenum: An in silico comparison with mutagenic and nonmutagenic carcinogens across tissues
Thompson CM, Hixon JG, Proctor DM, Haws LC, Suh M, Urban JD, Harris MA. 2012. Assessment of genotoxic potential of Cr(VI) in the mouse duodenum: An in silico comparison with mutagenic and nonmutagenic carcinogens across tissues. Regul Toxicol Pharmacol 64(1):68-76; doi: 10.1016/j.yrtph.2012.05.019
View AbstractComparison of the effects of hexavalent chromium in the alimentary canal of F344 rats and B6C3F1 mice following exposure in drinking water: Implications for carcinogenic modes of action
Thompson CM, Proctor DM, Suh M, Haws LC, Hebert CD, Mann JF, Shertzer HG, Hixon JG,Harris MA. 2012. Comparison of the effects of hexavalent chromium in the alimentary canal of F344 rats and B6C3F1 mice following exposure in drinking water: Implications for carcinogenic modes of action. Toxicol Sci 125(1):79-90; doi: 10.1093/toxsci/kfr280.
View AbstractGenome-wide gene expression analysis of Cr(VI) effects in Fisher rat small intestinal epithelium
Kim S, Kopec A, Forgacs AL, Thompson CM, Zacharewski T. Genome-wide gene expression analysis of Cr(VI) effects in Fisher rat small intestinal epithelium. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
View AbstractDuodenal GSH/GSSG ratios in mice following oral exposure to Cr(VI)
Thompson CM, Proctor DM, Harris MA. 2012. Duodenal GSH/GSSG ratios in mice following oral exposure to Cr(VI). Toxicol Sci 126(1):287-288; doi: 10.1093/toxsci/kfr337.
View AbstractPhysiologically-based pharmacokinetic model for mice, rats and humans orally-exposed to chromium
Kirman CR, Hays SM, Aylward LL, Suh M, Proctor D. 2012. Physiologically-based pharmacokinetic model for mice, rats and humans orally-exposed to chromium. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
View AbstractComparative toxicogenomic analysis of Cr(VI) effects in rat and mouse small intestine
Kopec A, Forgacs AL, Kim S, Thompson CM, Zacharewski T. Comparative toxicogenomic analysis of Cr(VI) effects in rat and mouse small intestine. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
View AbstractK-ras codon 12 GGT to GAT mutation is not elevated in the duodenum of mice subchronically exposed to hexavalent chromium in drinking water
O’Brien TJ, Hao D, Suh M, Proctor D, Thompson CM, Harris MA, Parsons BL, Meyers MB. 2012. K-ras codon 12 GGT to GAT mutation is not elevated in the duodenum of mice subchronically exposed to hexavalent chromium in drinking water. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.
View AbstractMode of action for intestinal carcinogenesis of ingested hexavalent chromium in mice
Proctor DM, Thompson CM, Suh M, Haws LC, Harris MA. 2012. Mode of action for intestinal carcinogenesis of ingested hexavalent chromium in mice. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
View AbstractAssessment of genotoxic potential of Cr(VI) in the mouse duodenum via toxicogenomic profiling
Thompson CM, Hixon JG, Kopec AK, Harris MA, Proctor DM, Haws LC. Assessment of genotoxic potential of Cr(VI) in the mouse duodenum via toxicogenomic profiling. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
View Abstract2011 (6 POSTS)
Investigation of the mode of action underlying the tumorigenic response induced in B6C3F1 mice exposed orally to hexavalent chromium
Thompson CM, Proctor DM, Haws LC, Hebert CD, Grimes SD, Shertzer HG, Kopec AK, Hixon JG, Zacharewski TR, Harris MA. 2011. Investigation of the mode of action underlying the tumorigenic response induced in B6C3F1 mice exposed orally to hexavalent chromium. Toxicol Sci 123(1):58-70; doi: 10.1093/toxsci/kfr164.
View AbstractApplication of the U.S. EPA mode of action framework for purposes of guiding future research: A case study involving the oral carcinogenicity of hexavalent chromium
Thompson CM, Haws LC, Harris MA, Gatto NM, Proctor DM. 2011. Application of the U.S. EPA mode of action framework for purposes of guiding future research: A case study involving the oral carcinogenicity of hexavalent chromium. Toxicol Sci 119(1):20-40; doi: 10.1093/toxsci/kfq320.
View AbstractResearch plan to fill data gaps in the mode of action for cancer risk assessment of hexavalent chromium in drinking water
Haws L, Proctor D, Thompson C, Harris M. Research plan to fill data gaps in the mode of action for cancer risk assessment of hexavalent chromium in drinking water. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
View AbstractComparison of basal and CrVI-mediated solute carrier gene expression in rodent duodenal epithelium
Kim S, Thompson CM, Kopec AK, Harris MA, Zacharewski TR. Comparison of basal and CrVI-mediated solute carrier gene expression in rodent duodenal epithelium. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
View AbstractUse of mode of action and pharmacokinetic findings to inform the cancer risk assessment of ingested Cr(VI): A case study
Proctor D, Haws L, Thompson C, Harris M. 2011. Use of mode of action and pharmacokinetics to inform the cancer risk assessment of ingested Cr(VI): A case study. Presented at the Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
View AbstractUsing mode of action data to guide quantitative cancer risk assessment: A case study of hexavalent chromium in drinking water
Proctor D, Meek B. Using mode of action data to guide quantitative cancer risk assessment: A case study of hexavalent chromium in drinking water. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
View Abstract2010 (2 POSTS)
Occupational exposure to hexavalent chromium and cancers of the gastrointestinal tract: A meta-analysis
Gatto NM, Kelsh MA, Mai DH, Suh M, Proctor DM. 2010. Occupational exposure to hexavalent chromium and cancers of the gastrointestinal tract: A meta-analysis. Cancer Epidemiol 34(4):388-399; doi: 10.1016/j.canep.2010.03.013.
View AbstractEvaluation of hexavalent chromium in sediment pore water of the Hackensack River, New Jersey, USA
Driscoll SK, McArdle ME, Plumlee MH, Proctor D. 2010. Evaluation of hexavalent chromium in sediment pore water of the Hackensack River, New Jersey, USA. Environ Toxicol Chem 29(3):617-20; doi: 10.1002/etc.93.
View Abstract