Publications
Haws, Laurie Couture, Ph.D., DABT (223 POSTS)
2012 (12 POSTS)
Hexavalent chromium reduction kinetics in rodent stomach contents
Proctor DM, Suh M, Aylward LL, Kirman CR, Harris MA, Thompson CM, Gürleyük H, Gerads R, Haws LC, Hays SM. 2012. Hexavalent chromium reduction kinetics in rodent stomach contents. Chemosphere 89(5):487-493; doi: 10.1016/j.chemosphere.2012.04.065.
View AbstractUS EPA’s proposed toxicity values for TCDD: Implications for decision-making regarding the safety of foods in the United States
Haws L, Fitzgerald L, Burkhalter K, Wikoff D. US EPA’s proposed toxicity values for TCDD: Implications for decision-making regarding the safety of foods in the United States. Presented at the Society of Toxicology’s 51st Annual Meeting, San Francisco, CA, March 2012.
View AbstractAssessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis
Thompson CM, Fedorov Y, Brown DD, Suh M, Proctor DM, Kuriakose L, Haws L, Harris MA. 2012. Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis. PLoS ONE 7(8):e42720; doi: 10.1371/journal.pone.0042720.
View AbstractAssessment of genotoxic potential of Cr(VI) in the mouse duodenum: An in silico comparison with mutagenic and nonmutagenic carcinogens across tissues
Thompson CM, Hixon JG, Proctor DM, Haws LC, Suh M, Urban JD, Harris MA. 2012. Assessment of genotoxic potential of Cr(VI) in the mouse duodenum: An in silico comparison with mutagenic and nonmutagenic carcinogens across tissues. Regul Toxicol Pharmacol 64(1):68-76; doi: 10.1016/j.yrtph.2012.05.019
View AbstractComparison of the effects of hexavalent chromium in the alimentary canal of F344 rats and B6C3F1 mice following exposure in drinking water: Implications for carcinogenic modes of action
Thompson CM, Proctor DM, Suh M, Haws LC, Hebert CD, Mann JF, Shertzer HG, Hixon JG,Harris MA. 2012. Comparison of the effects of hexavalent chromium in the alimentary canal of F344 rats and B6C3F1 mice following exposure in drinking water: Implications for carcinogenic modes of action. Toxicol Sci 125(1):79-90; doi: 10.1093/toxsci/kfr280.
View AbstractNatural gas exploration and production in the Barnett Shale: Assessment of exposures to volatile organic compounds (VOCs)
Perry C, Tachovsky JA, Ke M, Urban J, Haws L. Natural gas exploration and production in the Barnett Shale: Assessment of exposures to volatile organic compounds (VOCs). Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
View AbstractMode of action for intestinal carcinogenesis of ingested hexavalent chromium in mice
Proctor DM, Thompson CM, Suh M, Haws LC, Harris MA. 2012. Mode of action for intestinal carcinogenesis of ingested hexavalent chromium in mice. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
View AbstractAssessment of genotoxic potential of Cr(VI) in the mouse duodenum via toxicogenomic profiling
Thompson CM, Hixon JG, Kopec AK, Harris MA, Proctor DM, Haws LC. Assessment of genotoxic potential of Cr(VI) in the mouse duodenum via toxicogenomic profiling. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
View AbstractApplication of machine learning in the development of a weighting framework for evaluating estimates of relative potency for dioxin-like compounds
Wikoff D, DeVito M, Walker N, Hixon G, Harris M, Tachovsky A, Birnbaum L, Haws L. Application of machine learning in the development of a weighting framework for evaluating estimates of relative potency for dioxin-like compounds. Presented at Society of Toxicology 51st Annual Meeting, San Francisco, CA, March 2012.
View Abstract2011 (10 POSTS)
Derivation of an oral reference dose and drinking water screening level for sulfolane using benchmark dose modeling
Thompson C, Perry C, Gaylor D, Tachovsky A, Burkhalter B, Haws L. Derivation of an oral reference dose and drinking water screening level for sulfolane using benchmark dose modeling. Presented at Society of Toxicology 50th Annual Meeting, Washington DC, March 2011.
View AbstractInvestigation of the mode of action underlying the tumorigenic response induced in B6C3F1 mice exposed orally to hexavalent chromium
Thompson CM, Proctor DM, Haws LC, Hebert CD, Grimes SD, Shertzer HG, Kopec AK, Hixon JG, Zacharewski TR, Harris MA. 2011. Investigation of the mode of action underlying the tumorigenic response induced in B6C3F1 mice exposed orally to hexavalent chromium. Toxicol Sci 123(1):58-70; doi: 10.1093/toxsci/kfr164.
View AbstractBTEX serum levels in the general U.S. population: An analysis of 2003-2004 NHANES dataset
Urban J, Fitzgerald L, Burkhalter B, Staskal D, Harris M, Haws L. BTEX serum levels in the general U.S. population: An analysis of 2003-2004 NHANES dataset. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
View AbstractApplication of the U.S. EPA mode of action framework for purposes of guiding future research: A case study involving the oral carcinogenicity of hexavalent chromium
Thompson CM, Haws LC, Harris MA, Gatto NM, Proctor DM. 2011. Application of the U.S. EPA mode of action framework for purposes of guiding future research: A case study involving the oral carcinogenicity of hexavalent chromium. Toxicol Sci 119(1):20-40; doi: 10.1093/toxsci/kfq320.
View AbstractDevelopment of a consensus-based weighting framework for evaluating estimates of relative potency for dioxin-like compounds that includes consideration of data from human cells
Haws LC, DeVito MJ, Walker NJ,Harris MA, Tachovsky JA, Birnbaum LS, Farland WH, Wikoff DS. Development of a consensus-based weighting framework for evaluating estimates of relative potency for dioxin-like compounds that includes consideration of data from human cells. Presented at Dioxin 2011, Brussels, Belgium, August 2011.
Assessment of the US EPA’s proposed toxicological values for TCDD for regulation of dioxin-like compounds in foods: Bridging the science divide in a global market
Haws LC, Fitzgerald L, Burkhalter B, Harris M, Wikoff DS. Assessment of the US EPA’s proposed toxicological values for TCDD for regulation of dioxin-like compounds in foods: Bridging the science divide in a global market. Presented at Dioxin 2011, Brussels, Belgium, August 2011.
Derivation of relative potency estimates using benchmark dose modeling: A case study with TCDF
Wikoff DS, Thompson C, Walker N, DeVito M, Harris M, Birnbaum L, Haws L. Derivation of relative potency estimates using benchmark dose modeling: A case study with TCDF. Presented at Dioxin 2011, Brussels, Belgium, August 2011.
VOC serum levels in the general U.S. population: An analysis of the 2003-2004 NHANES dataset
Fitzgerald L, Burkhalter B, Urban J, Staskal D, Harris M, Haws L. VOC serum levels in the general U.S. population: An analysis of the 2003-2004 NHANES dataset. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011
View AbstractResearch plan to fill data gaps in the mode of action for cancer risk assessment of hexavalent chromium in drinking water
Haws L, Proctor D, Thompson C, Harris M. Research plan to fill data gaps in the mode of action for cancer risk assessment of hexavalent chromium in drinking water. Presented at Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
View AbstractUse of mode of action and pharmacokinetic findings to inform the cancer risk assessment of ingested Cr(VI): A case study
Proctor D, Haws L, Thompson C, Harris M. 2011. Use of mode of action and pharmacokinetics to inform the cancer risk assessment of ingested Cr(VI): A case study. Presented at the Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
View Abstract2010 (12 POSTS)
Serum concentrations of dioxin-like compounds in a population in Midland, Michigan: An evaluation of the impact of soil exposures
Harris M, Tachovsky JA, Staskal-Wikoff D, Aylward L, Burkhalter B, Simon T, Haws L. Serum concentrations of dioxin-like compounds in a population in Midland, Michigan: An evaluation of the impact of soil exposures. Presented at Dioxin 2010, San Antonio, TX, September 2010.