Publications
Chad Thompson (162 POSTS)
2011 (11 POSTS)
Utilizing toxicogenomic data to understand chemical mechanism of action in risk assessment
Wilson VS, Keshava N, Hester S, Segal D, Chiu W, Thompson CM, Euling SY. 2013. Utilizing toxicogenomic data to understand chemical mechanism of action in risk assessment. Toxicol Appl Pharmacol 271(3):299–308; doi: 10.1016/j.taap.2011.01.017.
View AbstractUse of mode of action and pharmacokinetic findings to inform the cancer risk assessment of ingested Cr(VI): A case study
Proctor D, Haws L, Thompson C, Harris M. 2011. Use of mode of action and pharmacokinetics to inform the cancer risk assessment of ingested Cr(VI): A case study. Presented at the Society of Toxicology 50th Annual Meeting, Washington, DC, March 2011.
View Abstract2010 (2 POSTS)
Physiological parameters and databases for PBPK modeling
Johns DO, Owens EO, Thompson CM, Sonawane B, Hattis D, Krishnan K. 2010. Physiological parameters and databases for PBPK modeling. Chapter 5 in: Quantitative Modeling in Toxicology. Krishnan K, Andersen M (eds.). Wiley, p. 107.
View AbstractFormaldehyde dehydrogenase: Beyond phase I metabolism
Thompson CM, Ceder R, Grafström RC. 2010. Formaldehyde dehydrogenase: Beyond phase I metabolism. Toxicol Lett 193(1):1-3; doi: 10.1016/j.toxlet.2009.11.023.
View Abstract2009 (3 POSTS)
Commentary: Mechanistic considerations for associations between formaldehyde exposure and nasopharyngeal carcinoma
Thompson CM, Grafstrom RC. 2009. Commentary: Mechanistic considerations for associations between formaldehyde exposure and nasopharyngeal carcinoma. Environ Health 8:53; doi: 10.1186/1476-069X-8-53.
View AbstractThe ontogeny, distribution and regulation of alcohol dehydrogenase 3: Implications for pulmonary physiology
Thompson CM, Sonawane B, Grafström RC. 2009. The ontogeny, distribution and regulation of alcohol dehydrogenase 3: Implications for pulmonary physiology. Drug Metab Disposit 37(8):1565-1571; doi: 10.1124/dmd.109.027904.
View AbstractDatabase for physiologically based pharmacokinetic (PBPK) modeling: Physiological parameters for healthy and health-impaired elderly
Thompson CM, Johns DO, Sonawane S, Barton HA, Hattis D, Tardif R, Krishnan K. 2009. Database for physiologically based pharmacokinetic (PBPK) modeling: Physiological parameters for healthy and health-impaired elderly. J Toxicol Environ Health B 12(1):1–24; doi: 10.1080/10937400802545060.
View Abstract2008 (5 POSTS)
Renal clearance parameters for PBPK model analysis of early lifestage differences in the disposition of environmental toxicants
DeWoskin RS, Thompson CM. 2008. Renal clearance parameters for PBPK model analysis of early lifestage differences in the disposition of environmental toxicants. Regul Toxicol Pharmacol 51(June):66–86; doi: 10.1016/j.yrtph.2008.02.005.
View AbstractA lifestage-specific spproach to hazard and dose-response characterization for children’s health risk assessment
Makris SL, Thompson CM, Euling SY, Selevan SG, Sonawane B. 2008. A lifestage-specific spproach to hazard and dose-response characterization for children’s health risk assessment. Birth Defects Res B 83(6):530–546; doi: 10.1002/bdrb.20176.
View AbstractUncertainties in biologically-based modeling of formaldehyde-induced respiratory cancer risk: Identification of key issues
Subramaniam RP, Chen C, Crump KS, Devoney D, Fox JF, Portier CJ, Schlosser PM, Thompson CM, White P. 2008. Uncertainties in biologically-based modeling of formaldehyde-induced respiratory cancer risk: Identification of key issues. Risk Analysis 28(4):907–923; doi: 10.1111/j.1539-6924.2008.01083.x.
View AbstractMechanistic and dose considerations for supporting adverse pulmonary physiology in response to formaldehyde
Thompson CM, Subramaniam RP, Grafström RC. 2008. Mechanistic and dose considerations for supporting adverse pulmonary physiology in response to formaldehyde. Toxicol Appl Pharmacol 233(3):355–359.
View AbstractApproaches for applications of physiologically based pharmacokinetic models in risk assessment
Thompson CM, Sonawane B, Barton HA, DeWoskin RS, Schlosser P, Lipscomb JC, Chiu W, Krishnan K. 2008. Approaches for applications of physiologically based pharmacokinetic models in risk assessment. J Toxicol Environ Health B 11(7):519–547; doi: 10.1080/10937400701724337.
View Abstract2007 (1 POST)
Mechanistic considerations for formaldehyde-induced bronchoconstriction involving S-nitrosoglutathione reductase
Thompson CM, Grafström RC. 2007. Mechanistic considerations for formaldehyde-induced bronchoconstriction involving S-nitrosoglutathione reductase. J Toxicol Environ Health A 71:244–248; doi: 10.1080/15287390701598259.
View Abstract2006 (1 POST)
Visión general de la evaluación del rieso en salud infantil empleando un enfoque por etapas de desarrollo
Barone S Jr., Brown RC, Euling S, Cohen Hubal E, Kimmel CA, Makris S, Moya J, Selevan SG, Sonawane B, Thomas T, Thompson CM. 2006. Visión general de la evaluación del rieso en salud infantil empleando un enfoque por etapas de desarrollo. Acta Toxicol Argent 14(Suppl):7–10.
2004 (1 POST)
Activation of G-proteins by morphine and codeine congeners: Insights to the relevance of O- and N-demethylated metabolites at μ- and δ-opioid receptors
Thompson CM, Wojno H, Greiner E, May EL, Rice KC, Selley DE. 2004. Activation of G-proteins by morphine and codeine congeners: Insights to the relevance of O- and N-demethylated metabolites at μ- and δ-opioid receptors. J Pharmacol Exper Therapeut 308(2):547–554; PMID: 14600248.
View Abstract2002 (1 POST)
Cytochromes P450 in brain: Function and significance
Strobel HW, Thompson CM, Antonovic L. 2001. Cytochromes P450 in brain: Function and significance. Curr Drug Metabol 2(2):199–214; doi: 10.2174/1389200013338577.
View Abstract2000 (1 POST)
Recombinant P450 2D18 metabolism of dopamine and arachidonic acid
Thompson CM, Capdevila JH, Strobel HW. 2000. Recombinant P450 2D18 metabolism of dopamine and arachidonic acid. J Pharmacol Exper Ther 294(3):1120–1130; doi: 10.1016/S0022-3565(24)39180-3.
View Abstract1998 (2 POSTS)
The vesicle transport protein, Vps33p, is an ATP binding protein that localizes to the cytosol in an energy dependent manner
Gerhardt B, Kordas TJ, Thompson CM, Patel P, Vida TV. 1998. The vesicle transport protein, Vps33p, is an ATP binding protein that localizes to the cytosol in an energy dependent manner. J Biol Chem 273(25):15818–15829; doi: 10.1074/jbc.273.25.15818.
View AbstractIsolation of partially purified P450 2D18 and characterization of activity towards the tricyclic antidepressants imipramine and desipramine
Thompson CM, Kawashima H, and Strobel HW. 1998. Isolation of partially purified P450 2D18 and characterization of activity towards the tricyclic antidepressants imipramine and desipramine. Arch Biochem Biophys 359(1):115–121; doi: 10.1006/abbi.1998.0892.
View Abstract1997 (2 POSTS)
Protein expression, characterization, and regulation of CYP4F4 and CYP4F5 cloned from rat brain
Kawashima H, Kusunose E, Thompson CM, and Strobel HW. 1997. Protein expression, characterization, and regulation of CYP4F4 and CYP4F5 cloned from rat brain. Arch Biochem Biophys 347(1):148–154 doi: 10.1006/abbi.1997.0342.
View Abstract